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A Lost Lady is a novel by American author Willa Cather, first published in 1923. It centers on Marian Forrester, her husband Captain Daniel Forrester, and their lives in the small western town of Sweet Water, along the Transcontinental Railroad. However, it is mostly told from the perspective of a young man named Niel Herbert, as he observes the decline of both Marian and the West itself, as it shifts from a place of pioneering spirit to one of corporate exploitation. Exploring themes of social class, money, and the march of progress, A Lost Lady was praised for its vivid use of symbolism and setting, and is considered to be a major influence on the works of F. Scott Fitzgerald. It has been adapted to film twice, with a film adaptation being released in 1924, followed by a looser adaptation in 1934, starring Barbara Stanwyck. A Lost Lady begins in the small railroad town of Sweet Water, on the undeveloped Western plains. The most prominent family in the town is the Forresters, and Marian Forrester is known for her hospitality and kindness. The railroad executives frequently stop by her house and enjoy the food and comfort she offers while there on business. A young boy, Niel Herbert, frequently plays on the Forrester estate with his friend. One day, an older boy named Ivy Peters arrives, and shoots a woodpecker out of a tree. He then blinds the bird and laughs as it flies around helplessly. Niel pities the bird and tries to climb the tree to put it out of its misery, but while climbing he slips, and breaks his arm in the fall, as well as knocking himself unconscious. Ivy takes him to the Forrester house where Marian looks after him. When Niel wakes up, he's amazed by the nice house and how sweet Marian smells. He doesn't't see her much after that, but several years later he and his uncle, Judge Pommeroy, are invited to the Forrester house for dinner. There he meets Ellinger, who he will later learn is Mrs. Forrester's lover, and Constance, a young girl his age.
Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
An account of one woman's life in the West during the second half of the nineteenth century from growing up on the Montana mining frontier to her ascent to young womanhood on a farm in southern California.
A haunting tribute to the heroic pioneers who shaped the American Midwest This powerful novel by Willa Cather is considered to be one of her finest works and placed Cather in the forefront of women novelists. It tells the stories of several immigrant families who start new lives in America in rural Nebraska. This powerful tribute to the quiet heroism of those whose struggles and triumphs shaped the American Midwest highlights the role of women pioneers, in particular. Written in the style of a memoir penned by Antonia’s tutor and friend, the book depicts one of the most memorable heroines in American literature, the spirited eldest daughter of a Czech immigrant family, whose calm, quite strength and robust spirit helped her survive the hardships and loneliness of life on the Nebraska prairie. The two form an enduring bond and through his chronicle, we watch Antonia shape the land while dealing with poverty, treachery, and tragedy. “No romantic novel ever written in America...is one half so beautiful as My Ántonia.” -H. L. Mencken Willa Cather (1873–1947) was an American writer best known for her novels of the Plains and for One of Ours, a novel set in World War I, for which she was awarded the Pulitzer Prize in 1923. She was elected a fellow of the American Academy of Arts and Sciences in 1943 and received the gold medal for fiction from the National Institute of Arts and Letters in 1944, an award given once a decade for an author's total accomplishments. By the time of her death she had written twelve novels, five books of short stories, and a collection of poetry.