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This up-to-the-minute and comprehensive resource lucidly covers gene therapy for lung diseases from existing technologies delivering foreign DNA to the lungs via the airways or circulation to promising new approaches for the further development of safe and efficient gene delivery systems.
One of the deadliest firefights in the history of the FBI occurred in 1986 in Miami, Florida. Lasting more than four minutes, the fight claimed the lives of two FBI agents and two extremely violent master criminals and severely injured five other FBI agents. On the 10th anniversary of the shootout, W. French Anderson, M.D., released his seminal study, "Forensic Analysis of the April 11, 1986, FBI Firefight". Anderson's report - the most well-researched, well-documented account of a gunfight in modern history - was available only to law enforcement personnel . . . until now. On the 20th anniversary of the firefight that revolutionized the way law enforcement agencies around the nation arm and train their agents, Dr. Anderson makes "Forensic Analysis" available to the public for the first time.
"Issues in bioethics, medicine, and healthcare continue to plague us - as patients as consumers, as citizens. Here, under one cover, are thirty of the most current and perceptive articles, culled from key medical, ethical, philosophical, legal and theological journals. Dr. Shannon once again offers - to healthcare professionals and students alike - access to this decade's core bioethics questions, a spectrum of viewpoints, and a wealth of insight."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
Traces the history of gene therapy research and discusses the politics involved in this medical revolution.
We've all heard that a father's involvement enriches the lives of children. But how much have we heard about how having a child affects a father's life? As Peter Gray and Kermyt Anderson reveal, fatherhood actually alters a man's sexuality, rewires his brain, and changes his hormonal profile. His very health may suffer—in the short run—and improve in the long. These are just a few aspects of the scientific side of fatherhood explored in this book, which deciphers the findings of myriad studies and makes them accessible to the interested general reader. Since the mid-1990s Anderson and Gray, themselves fathers of young children, have been studying paternal behavior in places as diverse as Boston, Albuquerque, Cape Town, Kenya, and Jamaica. Their work combines the insights of evolutionary and comparative biology, cross-cultural analysis, and neural physiology to deepen and expand our understanding of fatherhood—from the intense involvement in childcare seen in male hunter-gatherers, to the prodigality of a Genghis Khan leaving millions of descendants, to the anonymous sperm donor in a fertility clinic. Looking at every kind of fatherhood—being a father in and out of marriage, fathering from a distance, stepfathering, and parenting by gay males—this book presents a uniquely detailed picture of how being a parent fits with men's broader social and work lives, how fatherhood evolved, and how it differs across cultures and through time.
Profiles more than 150 scientists from around the world who made important contributions to the field of biology, including Claude Bernard, Alexander Fleming, Mary-Claire King, Ronald Ross, and Tetsuko Takabe.
James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc ture we had divined from a minimum of experimental data and on theoretical argu ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. "It has not escaped our notice," Francis wrote, "that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material." By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act ". . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before" and, moreover, " ...
Ethical interpretations meet real life. Case studies and readings explore divergent views on morals in action.
Each issue lists papers published during the preceding year.