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Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. - Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage - Explains how nanomaterials can be manipulated to create more effective drug treatments - Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments
An exploration of human language from the perspective of the natural sciences, this outstanding book brings together leading specialists to discuss the scientific connection of language to disciplines such as mathematics, physics, chemistry and biology.
The demonstration of the basic brain mechanism through studying the partially commissure-sectioned case appears to be a most prom ising enterprise. The work with animals of HAMILTON and others in elucidating psychological brain process heretofore not imagined are mere indications of what the potential seems to be. Study of the partially disconnected patient seems equally revealing and productive in showing how many high level cognitive activities are managed in the cerebral flow of information. With respect to the issue of localization of function, it would seem clear that those cerebral areas clearly involved in the im mediate processing of raw sensory information can be selectively and specifically isolated and disconnected. In other words, the informational products of the long axonal type cells of Golgi, which MARCUS JACOBSON claims are the brain cells under strict genetic control, can be isolated, whereas the products of more complex and integrative mental activities which are managed by the more mutable Golgi type II cells do not seem to be so spec ifically disposed. Thus, these data suggest the lateralized spe cialities of the various left and right brain areas can make their contribution to the cerebral activities of the opposite hemisphere through almost any callosal area regardless of its size and loca tion. Indeed, this interpretation suggests to me that the long standing issue of the extent of localization could be better un derstood by considering the dichotomy in genetic specification as offered by HIRSCH and JACOBSON (1974).
In medieval Europe, cultural, political, and linguistic identities rarely coincided with modern national borders. As early as the end of the twelfth century, French rose to prominence as a lingua franca that could facilitate communication between people, regardless of their origin, background, or community. Between the twelfth and fifteenth centuries, literary works were written or translated into French not only in France but also across Europe, from England and the Low Countries to as far afield as Italy, Cyprus, and the Holy Land. Many of these texts had a broad European circulation and for well over three hundred years they were transmitted, read, studied, imitated, and translated.00Drawing on the results of the AHRC-funded research project Medieval Francophone Literary Culture Outside France, this volume aims to reassess medieval literary culture and explore it in a European and Mediterranean setting. The book, incorporating nineteen papers by international scholars, explores the circulation and production of francophone texts outside of France along two major axes of transmission: one stretching from England and Normandy across to Flanders and Burgundy, and the other running across the Pyrenees and Alps from the Iberian Peninsula to the Levant. In doing so, it offers new insights into how francophone literature forged a place for itself, both in medieval textual culture and, more generally, in Western cultural spheres.
This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.
The Routledge Companion to Planning in the Global South offers an edited collection on planning in parts of the world which, more often than not, are unrecognised or unmarked in mainstream planning texts. In doing so, its intention is not to fill a ‘gap’ that leaves this ‘mainstream’ unquestioned but to re-theorise planning from a deep understanding of ‘place’ as well as a commitment to recognise the diverse modes of practice that come within it. The chapters thus take the form not of generalised, ‘universal’ analyses and prescriptions, but instead are critical and located reflections in thinking about how to plan, act and intervene in highly complex city, regional and national contexts. Chapter authors in this Companion are not all planners, or are planners of very different kinds, and this diversity ensures a rich variety of insights, primarily based on cases, to emphasise the complexity of the world in which planning is expected to happen. The book is divided into a framing Introduction followed by five sections: planning and the state; economy and economic actors; new drivers of urban change; landscapes of citizenship; and planning pedagogy. This volume will be of interest to all those wanting to explore the complexities of planning practice and the need for new theories of knowledge from which to draw insight to face the challenges of the 21st century.
The “black car” has appeared both conspicuously and inconspicuously throughout the annals of fiction—its presence both mysterious and menacing, its appearance enough to pause your heart. It’s the sedan just within sight that seems to be mimicking your speed and movements as you walk down the dark deserted street late at night. As the hairs rise on the back of your neck you wonder, Who is behind the wheel and what is the driver’s intent? It’s The Black Car Business and its presence means your life is about to abruptly change. You try to assure yourself there’s nothing wrong, but your pace quickens nonetheless, and soon you’re running, desperate for that narrow sliver between two buildings to slip through, the one too narrow for the black car to pass through. It’s that car parked just down the block that sends chills down your spine and keeps you awake throughout the night. It’s the sanctuary you race toward when you’re being chased, only to explode when you turn the key. It’s the one that skids off the icy mountain overpass and plunges into the cavernous grotto. It’s where Clemenza garrotes Carlo just as he’s about to be driven to the airport. It’s The Black Car Business. Turn the pages as ten masters of the noir art befuddle and frighten you with their stories. We promise a read you’re sure to enjoy. Contributors: Eric Beetner, J. Carson Black, Cheryl Bradshaw, Diane Capri, Jeffery Hess, Lawrence Kelter, Dana King, Allan Leverone, Simon Wood, and Vincent Zandri.
Mohan and Oliver have been very fortunate to have intimate views into the data challenges that face the largest organizations and institutions across every possible industry—and what they have been hearing about for some time is how the business needs to use data and analytics to their advantage. They continually hear the same issues, such as: We're spending valuable meeting time wondering why everyone's data doesn't match up. We can't leverage our economies of scale while remaining agile with data. We need self-serve apps that let the enterprise experiment with data and accelerate the development process. We need to get on a more predictive curve to ensure long-term success. To really address the data concerns of today's enterprise, they wanted to find a way to help enterprises achieve the success they seek. Not as a prescriptive process—but a methodology to become agile and leverage data and analytics to drive a competitive advantage. You know, it's amazing what can happen when two people with very different perspectives get together to solve a big problem. This evolutionary guide resulted from the a-ha moment between these two influencers at the top of their fields—one, an academic researcher and consultant, and the other, a longtime analytics practitioner and chief product officer at Teradata. Together, they created a powerful framework every type of business can use to connect analytic power, business practices, and human dynamics in ways that can transform what is currently possible.
Shoestring Business Guides: Starting a Web Design Business will show you everything you need to know to start your own web design and hosting business. Written by a serial entrepreneur, veteran web designer, and all-around "computer geek", this book will cover the most important information you need to consider when starting your own web design business. Starting a Web Design Business is filled with practical, useful information sure to get your new business off to a good start.Starting a Web Design Business does not cover the specifics of coding in HTML, CSS, or scripting languages. There are many good books that cover these particular topics. Starting a Web Design Business focuses instead on the specifics or starting and running the business from the perspective of someone who has done exactly this.In the time since the first edition of this book was originally published (2009), some of the material has become dated - particularly some of the references to software. Nonetheless, there is still a lot of valid and useful material in this little book. The price of this first edition has been discounted as much as possible in an effort to be fair to readers.
Distribute Actionable, Timely BI with Microsoft® SQL Server® 2016 and Power BI Drive better, faster, more informed decision making across your organization using the expert tips and best practices featured in this hands-on guide. Delivering Business Intelligence with Microsoft SQL Server 2016, Fourth Edition, shows, step-by-step, how to distribute high-performance, custom analytics to users enterprise-wide. Discover how to build BI Semantic Models, create data marts and OLAP cubes, write MDX and DAX scripts, and share insights using Microsoft client tools. The book includes coverage of self-service business intelligence with Power BI. • Understand the goals and components of successful BI • Build data marts, OLAP cubes, and Tabular models • Load and cleanse data with SQL Server Integration Services • Manipulate and analyze data using MDX and DAX scripts and queries • Work with SQL Server Analysis Services and the BI Semantic Model • Author interactive reports using SQL Server Data Tools • Create KPIs and digital dashboards • Implement time-based analytics • Embed data model content in custom applications using ADOMD.NET • Use Power BI to gather, model, and visualize data in a self-service environment