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The renowned AIDS researcher Robert Gallo tells his story of scientific breakthrough in a riveting portrait of the people, the politics, and the pace of modern scientific discovery.
After experiencing the SARS outbreak in 2003, Hong Kong, Singapore, and Taiwan all invested in various techniques to mitigate future pandemics involving myriad cross-species interactions between humans and birds. In some locations microbiologists allied with veterinarians and birdwatchers to follow the mutations of flu viruses in birds and humans and create preparedness strategies, while in others, public health officials worked toward preventing pandemics by killing thousands of birds. In Avian Reservoirs Frédéric Keck offers a comparative analysis of these responses, tracing how the anticipation of bird flu pandemics has changed relations between birds and humans in China. Drawing on anthropological theory and ethnographic fieldwork, Keck demonstrates that varied strategies dealing with the threat of pandemics—stockpiling vaccines and samples in Taiwan, simulating pandemics in Singapore, and monitoring viruses and disease vectors in Hong Kong—reflect local geopolitical relations to mainland China. In outlining how interactions among pathogens, birds, and humans shape the way people imagine future pandemics, Keck illuminates how interspecies relations are crucial for protecting against such threats.
Virus Hunt is a tale of scientific endeavour. Tracing the fascinating twenty year quest to find the origin of the virus that causes AIDS, Dorothy H. Crawford takes us on a journey around the world, to recount the vital research that eventually unravelled how, when, and where the virus first infected humans.
Presents the history of deadly viruses, their effects on people, and the research of scientists to discover and develop treatments against them.
A New York Times Notable Book The man who led the battle against Ebola in The Hot Zone teams up with the bestselling co-author of Mind Hunter to chronicle his extraordinary thirty-year career fighting deadly viruses. For three decades, Dr. C. J. Peters was on the front lines of our biological battle against “hot” viruses around the world. In the course of that career, he learned countless lessons about our interspecies turf wars with infectious agents. Called in to contain an outbreak of deadly hemorrhagic fever in Bolivia, he confronted the despair of trying to save a colleague who accidentally infected himself with an errant scalpel. Working in Level 4 labs on the Machupo and Ebola viruses, he saw time and again why expensive high-tech biohazard containment equipment is only as safe as the people who use it. Because of new, emerging viruses, and the return of old, “vanquished” ones for which vaccines do not exist, there remains a very real danger of a new epidemic that could, without proper surveillance and early intervention, spread worldwide virtually overnight. And the possibility of foreign countries or terrorist groups using deadly airborne viruses—the poor man’s nuclear arsenal—looms larger than ever. High-octane science writing at its best and most revealing, Virus Hunter is a thrilling first-person account of what it is like to be a warrior in the Hot Zone.
When a new influenza virus emerges that is able to be transmitted between humans, it spreads globally as a pandemic, often with high mortality. Enormous social disruption and substantial economic cost can result. The 1918 Spanish influenza pandemic was undoubtedly the most devastating influenza pandemic to date, and it has been Dr Robert Websters lifes work to figure out how and why. In so doing he has made a remarkable contribution to our understanding of the evolution of influenza viruses and how to control them. A century on, Flu Hunter is a gripping account of the tenacious scientific detective work involved in revealing the secrets of this killer virus. Dubbed Flu Hunter by Smithsonian Magazine in 2006, Dr Webster began his research in the early 1960s with the insight that the natural ecology of most influenza viruses is among wild aquatic birds. Painstaking tracking and testing of thousands of birds eventually led him and the other scientists involved to establish a link between these bird virus reservoirs and human influenza pandemics. Some of this fascinating scientific work involved exhuming bodies of Spanish flu victims from the Arctic permafrost in a search for tissue samples containing genetic material from the virus. Could a global influenza pandemic occur again? Websters warning is clear: "... it is not only possible, it is just a matter of when."
"The "Indiana Jones" of virus hunters reveals the complex interactions between humans and viruses, and the threat from viruses that jump from species to species"-- Provided by publisher.
BBC Radio 4's celebrated THE LIFE SCIENTIFIC has featured some of the world's most renowned experts in the field of deadly viruses. The interviews make sobering reading, a reminder of all the deadly viruses that have threatened global health, and why for the scientists working on the front line in the war against viruses, the arrival of Covid-19 came as no surprise. Among the contributors to this all-too-timely book are: Jeremy Farrar, before he became Director of the Wellcome Trust, worked in an Infectious Diseases Hospital in Vietnam. He was on the frontline tackling SARS and nine months later a highly pathogenic strain of bird flu, H5N1. Peter Piot was at the forefront of the Ebola epidemic in West Africa. He was the first to identify HIV in Africa. It took him fifteen years to persuade the world that it was also a heterosexual disease. Later as Executive Director of UN AIDS he fought for years to get the UN to take the threat of HIV seriously. Jonathan Ball studies how viruses operate at the molecular level, hoping to find their Achilles' heel and so develop effective vaccines. During the West Africa Ebola epidemic, he studied how the genome of the Ebola virus evolved as it spread from Guinea to Liberia and Sierra Leone. He has shown that as this virus (which more happily lives in bats) infects more humans, it becomes ever more infectious. Wendy Barclay seeks to understand how viruses are able to jump from animals to humans and why some viruses are so much more dangerous to humans than others. Most Londoners had no idea they were infected during the Swine Flu pandemic of 2009. The Bird Flu epidemic in Asia claimed thousands of lives Kate Jones is a bat specialist who works on how ecological changes and human behaviour accelerate the spread of animal viruses into humans. Bats have been infected with coronaviruses for more than 10,000 years.
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The hunt for the origin of the AIDS virus began over twenty years ago. It was a journey that went around the world and involved painstaking research to unravel how, when, and where the virus first infected humans. Dorothy H. Crawford traces the story back to the remote rain forests of Africa - home to the primates that carry the ancestral virus - and reveals how HIV-1 first jumped from chimpanzees to humans in rural south east Cameroon. Examining how this happened, and how it then travelled back to Colonial west central Africa where it eventually exploded as a pandemic, she asks why and how it was able to spread so widely. From hospital intensive care wards to research laboratories and the African rain forests, this is the wide-ranging story of a killer virus and a tale of scientific endeavour.