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One of the highest-ranking defectors from Scientology exposes the secret inner workings of the powerful organization in this remarkable memoir that is “not only a cautionary tale but also an inspiring story of resilience” (Leah Remini, New York Times bestselling author). Mike Rinder’s parents began taking him to their local Scientology center when he was five years old. After high school, he signed a billion-year contract and was admitted into Scientology’s elite inner circle, the Sea Organization. Brought to founder L. Ron Hubbard’s yacht and promised training in Hubbard’s most advanced techniques, Rinder was instead put to work swabbing the decks. Still, Rinder bought into the doctrine that his personal comfort was secondary to the higher purpose of Hubbard’s world-saving mission, swiftly rising through the ranks. In the 1980s, Rinder became Scientology’s international spokesperson and the head of its powerful Office of Special Affairs. He helped negotiate Scientology’s pivotal tax exemption from the IRS and engaged with the organization’s prominent celebrity members, including Tom Cruise, Lisa Marie Presley, and John Travolta. Yet Rinder couldn’t shake a nagging feeling that something was amiss—Hubbard’s promises remained unfulfilled at his death, and his successor, David Miscavige, was a ruthless and vindictive man who did not hesitate to confine many top Scientologists, Mike among them, to a makeshift prison known as the Hole. In 2007, at the age of fifty-two, Rinder finally escaped Scientology. Overnight, he became one of the organization’s biggest public enemies. He was followed, hacked, spied on, and tracked. But he refused to be intimidated and today helps people break free of Scientology. “An intensely personal, cathartic memoir of blind allegiance, betrayal, and liberation” (Kirkus Reviews, starred review), A Billion Years reveals the dark, dystopian truth about Scientology as never before.
A twelfth-century poem by the creator of the Arthurian romance describes the courageous exploits and triumphs of a brave lord who tries to win back his deserted wife's love
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.
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