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Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging an
This book provides detailed, state-of-the-art information and guidelines on the latest developments, innovations, and clinical procedures in image-guided and adaptive radiation therapy. The first section discusses key methodological and technological issues in image-guided and adaptive radiation therapy, including use of implanted fiducial markers, management of respiratory motion, image-guided stereotactic radiosurgery and stereotactic body radiation therapy, three-dimensional conformal brachytherapy, target definition and localization, and PET/CT and biologically conformal radiation therapy. The second section provides practical clinical information on image-guided adaptive radiation therapy for cancers at all common anatomic sites and for pediatric cancers. The third section offers practical guidelines for establishing an effective image-guided adaptive radiation therapy program.
Accuracy requirements in radiation oncology have been defined in multiple publications; however, these have been based on differing radiation technologies. In the meantime, the uncertainties in radiation dosimetry reference standards have been reduced and more detailed patient outcome data are available. No comprehensive literature on accuracy and uncertainties in radiotherapy has been published so far. The IAEA has therefore developed a new international consensus document on accuracy requirements and uncertainties in radiation therapy, to promote safer and more effective patient treatments. This publication addresses accuracy and uncertainty issues related to the vast majority of radiotherapy departments including both external beam radiotherapy and brachytherapy. It covers clinical, radiobiological, dosimetric, technical and physical aspects.
This unique, full-color reference offers a total team approach to radiation oncology treatment planning, incorporating the newest imaging techniques and offering a comprehensive discussion of clinical, physical, biological and technical aspects. A clear focus on the application of physical and clinical concepts to solve treatment planning problems helps you provide effective, state-of-the-art care for cancer patients. With authoritative coverage of the latest in sophisticated radiation oncology treatment modalities, the 4th Edition of Khan’s Treatment Planning in Radiation Oncology is an essential resource for the radiation oncologist, medical physicist, dosimetrist, and radiation therapist.
Head and neck cancer is a very common cancer worldwide with an estimated 500,000 individuals diagnosed each year. In the United States an average of 39,000 new cases are reported each year representing between 3 to 5% of all new cancer cases diagnosed annually. Head and neck cancers are more common in men and in individuals over the age of 50. The treatment of head and neck cancer is extremely challenging and involves insight and expertise from multiple disciplines. Multidisciplinary Management of Head and Neck Cancer is a comprehensive textbook looking at different aspects of head and neck cancer, including the diagnosis, treatment and outcomes for patients with this disease. The chapters written by world-renowned experts cover the entire discipline of head and neck oncology and include discussion of the role of HPV infections, advances in radiotherapy, new surgical techniques, novel agents in thyroid therapy and more. The book is designed to be both practical and comprehensive for the physicians treating this complex disease. Features of Multidisciplinary Management of Head and Neck Cancer include: A chapter on the role of HPV infections in head and neck cancer A chapter on new advances in radiotherapy for head and neck cancer, including review IMRT, new standards and potential pitfalls Detailed discussion of the role of chemotherapy in head and neck cancer, including commonly used drugs and how to combine them with radiotherapy to improve patient outcomes Detailed discussion on incorporating novel agents with radiotherapy Detailed discussion of novel therapeutics in head and neck cancer, including new drugs and biologics
The emphasis on cancer management in the past was based primarily on control rates from multidisciplinary input in management. There has always been a recognition that one would like to achieve the best result with the least complication, but never has there been any major emphasis on evidence-based outcome studies, nor on functional preservation and quality of life. The authors of this book have dealt very effectively with the various tumor types in head and neck cancer with the experts in the ? eld of management. The contents range from epidemiology and treatment outcome, treatment techniques with the potential impact on the quality of life such as dysphagia, to the various options relative to high technology radiation therapy programs for mana- ment. The potential for improving form and function through surgical care as an integrated part of the program is dealt with very effectively as well as the potentials for chemotherapy and the use of targeted agents have on quality of life issues. The volume also addresses toxicity, quality of life, and techniques for prevention of adverse effects, as well as the potentials for rehabilitation and supportive care. The authors have clearly done an extraordinarily good job in addressing the mul- plicity of problems that impact upon the functional preservation and quality of life in head and neck radiation therapy. Philadelphia Luther W.
​This book provides a complete overview of the role of machine learning in radiation oncology and medical physics, covering basic theory, methods, and a variety of applications in medical physics and radiotherapy. An introductory section explains machine learning, reviews supervised and unsupervised learning methods, discusses performance evaluation, and summarizes potential applications in radiation oncology. Detailed individual sections are then devoted to the use of machine learning in quality assurance; computer-aided detection, including treatment planning and contouring; image-guided radiotherapy; respiratory motion management; and treatment response modeling and outcome prediction. The book will be invaluable for students and residents in medical physics and radiation oncology and will also appeal to more experienced practitioners and researchers and members of applied machine learning communities.
The thoroughly updated fifth edition of this landmark work has been extensively revised to better represent the rapidly changing field of radiation oncology and to provide an understanding of the many aspects of radiation oncology. This edition places greater emphasis on use of radiation treatment in palliative and supportive care as well as therapy.
Images from CT, MRI, PET, and other medical instrumentation have become central to the radiotherapy process in the past two decades, thus requiring medical physicists, clinicians, dosimetrists, radiation therapists, and trainees to integrate and segment these images efficiently and accurately in a clinical environment. Image Processing in Radiation
Over the past twenty-five years, proton therapy has become more prominent worldwide. It is an important component of clinical radiation therapy for both adult and pediatric clinical care. Due to the inherent ability of protons to spare normal tissue, protons will continue to develop and become increasingly important in radiation oncology. As such, Proton Therapy - Current Status and Future Directions reviews many aspects of proton care including the application of protons in modern clinical trials. It also reviews problems associated with the migration of proton care worldwide and examines the future direction of proton care. This project was created by colleagues at IntechOpen and was carefully managed by Romina Rovan. It has been a privilege to help coordinate the text and chapters designed to acknowledge the history, footprint, and growing interest of proton care worldwide. Proton management is now embedded in the clinical trials process. In pediatric care, proton delivery is embedded with photons for the management of pediatric malignancies and adult groups have initiated proton-specific clinical trials. A proton registry has been established and outcomes are under evaluation. Due to the inherent ability of protons to spare normal tissue, protons will continue to develop and become increasingly important in radiation oncology.