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Although many tumors of the upper respiratory tract are squamous cell carcinomas, the varied tissues of this region can give rise to a bewildering array of neoplasms. This text reviews the interpretation of biopsies of neoplasms and neoplasm-like entities arising in the head and neck region, including the ear. It discusses both neoplastic and non-neoplastic pathology to help make the correct diagnosis and guide patient management.
Although many tumors of the upper respiratory tract are squamous cell carcinomas, the varied tissues of this region can give rise to a bewildering array of neoplasms. This text reviews the interpretation of biopsies of neoplasms and neoplasm-like entities arising in the head and neck region, including the ear. It will discuss both neoplastic and non-neoplastic pathology to help make the correct diagnosis and guide patient management.
There is no single universal definition of the upper aerodigestive tract; for the purposes of this guideline, it encompasses the oral cavity, oropharynx, nasopharynx, hypopharynx, larynx, and paranasal sinuses. The vast majority of cancers at these sites are squamous cell carcinomas (National Head and Neck Cancer Audit, 2014). Some other cancers with less common histological diagnoses, such as mucosal melanomas of the upper aerodigestive tract, are also covered by this guideline.