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“Four players. It’s in the rules.” “Is this like, some sort of academic decathlon or something?” “Something like that.” Walkman-toting, guitar-playing Finn Mallory blames himself for his parents’ deaths and would do anything to turn back time and set things right. So, when he’s recruited into a secret club at his new school that specializes in competitive time travel games, Finn sees a world of opportunity open before him. The games, however, are far from benign. Competition is cutthroat. Scenarios are rigged. And the mysterious timekeepers who organize it all have no qualms about using—or disposing of—players to suit their own sinister plans. Now Finn must decide who he can trust while making peace with his past if he’s to have any hope of leading his team to victory and surviving his junior year. As the games commence, it’s time to press rewind.
A Practical Guide to Managing Clinical Trials is a basic, comprehensive guide to conducting clinical trials. Designed for individuals working in research site operations, this user-friendly reference guides the reader through each step of the clinical trial process from site selection, to site set-up, subject recruitment, study visits, and to study close-out. Topics include staff roles/responsibilities/training, budget and contract review and management, subject study visits, data and document management, event reporting, research ethics, audits and inspections, consent processes, IRB, FDA regulations, and good clinical practices. Each chapter concludes with a review of key points and knowledge application. Unique to this book is "A View from India," a chapter-by-chapter comparison of clinical trial practices in India versus the U.S. Throughout the book and in Chapter 10, readers will glimpse some of the challenges and opportunities in the emerging and growing market of Indian clinical trials.
After angering his father Zeus, the god Apollo is cast down from Olympus. Weak and disoriented, he lands in New York City as a regular teenage boy. Now, without his godly powers, the four-thousand-year-old deity must learn to survive in the modern wo
Welcome to The Sunbearer Trials, where teen semidioses compete in a series of challenges with the highest of stakes, in this electric new Mexican-inspired fantasy from Aiden Thomas, the New York Times bestselling author of Cemetery Boys. “Only the most powerful and honorable semidioses get chosen. I’m just a Jade. I’m not a real hero.” As each new decade begins, the Sun’s power must be replenished so that Sol can keep traveling along the sky and keep the chaotic Obsidian gods at bay. Sol selects ten of the most worthy semidioses to compete in the Sunbearer Trials. The winner carries light and life to all the temples of Reino del Sol, but the loser has the greatest honor of all—they will be sacrificed to Sol, their body melted down to refuel the Sun Stones, protecting the world for another ten years. Teo, a seventeen-year-old Jade semidiós and the trans son of the goddess of birds, isn't worried about the Trials . . . at least, not for himself. His best friend, Niya is a Gold semidiós and a shoo-in for the Trials, and while he trusts her abilities, the odds of becoming the sacrifice is one-in-ten. But then, for the first time in over a century, the impossible happens. Sol chooses not one, but two Jade competitors. Teo, and Xio, the thirteen-year-old child of the god of bad luck. Now they must compete in five trials against Gold opponents who are more powerful and better trained. Worst of all, Teo’s annoyingly handsome ex-best friend and famous semidiós Hero, Aurelio is favored to win. Teo is determined to get himself and his friends through the trials unscathed—for fame, glory, and their own survival.
Vampire slayer Buffy Summers adjusts to her partnership with Faith, the "shadow-self" slayer whose impulsive ways bring her closer and closer to danger.
This comprehensive set of essays documents the most important criminal, civil, and political trials in the United States from colonial times to the present, examining their impact on both legal history and popular culture. Crime and punishment are of perennial interest across the human species. Trials of the Century: An Encyclopedia of Popular Culture and the Law examines some of the most important (and infamous) cases in American history, placing them in both historical and legal context. Among the landmark cases considered in these two volumes are the 1692 Salem Witch Trials, the Scopes "Monkey" Trial, and the O.J. Simpson murder trial. A number of civil lawsuits and political trials are also included, such as the impeachment trials of Presidents Andrew Johnson and William Jefferson Clinton. Entries in the encyclopedia detail the events leading to each trial and introduce the key players, with a focus on judges, lawyers, witnesses, defendants, victims, media, and the public. In addition, the aftermath of the trial and its impact are analyzed from a scholarly, yet straightforward, perspective, emphasizing how the trial affected the law and society at large.
Excerpt from Trials, Vol. 1 of 2: A Tale Catherine, I desire that you don't interrupt your aunt, but attend to what she wishes to say to you observed 1\ir. Dorrington; and do, for heaven s sake, put that little beast of a'dog down; and he snatched him with violence from the lap of his poor little mistress, who, too much in terror of her father to rebel, sat in mute expectation of what she was to hear, trying from a variety of motives to suppress the tears, which could not, after all, be repelled; but which every now and then broke out in a stifled sob, as her aunt and her father alternately laid down to her the various duties of an elegant young gentle woman; duties which, it must he confessed, poor Catherine was sadly remiss in performing. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
"The powerful wizard Shazam has been destroyed and his vast responsibility for presiding over the realm of all magic has been shifted to his mightiest champion, Billy Batson. Such a job can only be performed from the Rock of Eternity -- thus, earth is without a defender to balance the worlds of magic and humanity, for the first time in centuries. Freddy Freeman wants to be that protector, but that is an honor that must be earned. Powerless, Freddy must embark on a quest to prove to the Gods that he is worthy to weld the power of Shazam"--Page 4 of cover
A complete guide to the key statistical concepts essential for the design and construction of clinical trials As the newest major resource in the field of medical research, Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs presents a timely and authoritative reviewof the central statistical concepts used to build clinical trials that obtain the best results. The referenceunveils modern approaches vital to understanding, creating, and evaluating data obtained throughoutthe various stages of clinical trial design and analysis. Accessible and comprehensive, the first volume in a two-part set includes newly-written articles as well as established literature from the Wiley Encyclopedia of Clinical Trials. Illustrating a variety of statistical concepts and principles such as longitudinal data, missing data, covariates, biased-coin randomization, repeated measurements, and simple randomization, the book also provides in-depth coverage of the various trial designs found within phase I-IV trials. Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs also features: Detailed chapters on the type of trial designs, such as adaptive, crossover, group-randomized, multicenter, non-inferiority, non-randomized, open-labeled, preference, prevention, and superiority trials Over 100 contributions from leading academics, researchers, and practitioners An exploration of ongoing, cutting-edge clinical trials on early cancer and heart disease, mother-to-child human immunodeficiency virus transmission trials, and the AIDS Clinical Trials Group Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs is an excellent reference for researchers, practitioners, and students in the fields of clinicaltrials, pharmaceutics, biostatistics, medical research design, biology, biomedicine, epidemiology,and public health.