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Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Most scientific training programs provide little or no systematic introduction to the issues, challenges, and obstacles that prevent effective research translation, even though these are the key steps that enable high-impact basic science to ultimately result in significant clinical advances that improve patient outcome. This volume will provide an overview of key issues in translation of research from “bedside to bench to bedside”, not only from the perspective of the key funding agencies, but also from the scientists and clinicians who are currently involved in the translational research process. It will attempt to offer insight into real-world experience with intellectual property and technology transfer activities that can help move auditory technologies ahead, as scientists and clinicians typically have little or no formal training in these areas. Translational Research in Audiology and the Hearing Sciences will be aimed at graduate students and postdoctoral investigators, as well as professionals and academics. It is intended to function as a high-profile and up-to-date reference work on Translational Research in the auditory sciences, emphasizing research programs in the traditional areas including drugs and devices, as well as less traditional, still emerging, areas such as sensorineural hearing loss, auditory processing disorder, cochlear implants and hearing aids, and tinnitus therapies.
Evaluating and Conducting Research in Audiology is the first research methods textbook that is specific to the field of audiology and designed to serve as an academic textbook for audiology graduate students. This text can also be accessible for audiology practitioners who are interested in clinical and applied research. The comprehensive coverage includes materials for multiple courses within audiology degree programs, including research methods, analysis of professional literature, evidence-based practice, and capstone research projects. Classroom tested, and written by authors who have extensive backgrounds in publishing and editing, this text provides knowledge that is required in evaluating, conducting, and disseminating research. The book is separated into three sections: (a) research methods; (b) evidence-based practice; and (c) conducting and disseminating research. Together, these sections provide a detailed coverage of the research methods that are relevant to conducting research, particularly in the field of Audiology. Key Features: * Learning outcomes at the beginning of each chapter * End of chapter reviews including key points and study questions * Audiology-specific examples, research methods, and study designs * “Golden Nugget” boxes throughout the book containing valuable information related to the critical concepts * In-depth discussion of qualitative research methods, survey research methods, and systematic reviews to motivate students and early career researchers to consider these methodologies in their research
Progress in Medicinal Chemistry, Volume 61 provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors. - Provides extended, timely reviews of topics in medicinal chemistry - Contains targets and technologies relevant to the discovery of tomorrow's drugs - Presents analyses of successful drug discovery programs
Language development, and the challenges it can present for individuals who are deaf or hard-of-hearing, have long been a focus of research, theory, and practice in D/deaf studies and deaf education. Over the past 150 years, but most especially near the end of the 20th and beginning of the 21st century, advances in the acquisition and development of language competencies and skills have been increasing rapidly. This volume addresses many of those accomplishments as well as remaining challenges and new questions that have arisen from multiple perspectives: theoretical, linguistic, social-emotional, neuro-biological, and socio-cultural. Contributors comprise an international group of prominent scholars and practitioners from a variety of academic and clinical backgrounds. The result is a volume that addresses, in detail, current knowledge, emerging questions, and innovative educational practice in a variety of contexts. The volume takes on topics such as discussion of the transformation of efforts to identify a "best" language approach (the "sign" versus "speech" debate) to a stronger focus on individual strengths, potentials, and choices for selecting and even combining approaches; the effects of language on other areas of development as well as effects from other domains on language itself; and how neurological, socio-cognitive, and linguistic bases of learning are leading to more specialized approaches to instruction that address the challenges that remain for deaf and hard-of-hearing individuals. This volume both complements and extends The Oxford Handbook of Deaf Studies and Deaf Education, Volumes 1 and 2, going further into the unique challenges and demands for deaf or hard-of-hearing individuals than any other text and providing not only compilations of what is known but setting the course for investigating what is still to be learned.
The most comprehensive, multi-disciplinary text in the field, Cummings Otolaryngology: Head and Neck Surgery, 7th Edition, provides detailed, practical answers and easily accessible clinical content on the complex issues that arise for otolaryngologists at all levels, across all subspecialties. This award-winning text is a one-stop reference for all stages of your career—from residency and board certification through the challenges faced in daily clinical practice. Updated content, new otology editor Dr. Howard W. Francis, and new chapters and videos ensure that this 7th Edition remains the definitive reference in today's otolaryngology. - Brings you up to date with the latest minimally invasive procedures, recent changes in rhinology, and new techniques and technologies that are shaping patient outcomes. - Contains 12 new chapters, including Chronic Rhinosinusitis, Facial Pain, Geriatric Otology, Middle Ear Endoscopic Surgery, Pediatric Speech Disorders, Pediatric Cochlear Implantation, Tongue-Ties and Lip Ties, Laryngotracheal Clefts, and more. - Covers recent advances and new approaches such as the Draf III procedure for CRS affecting the frontal recess, endoscopic vidian and posterior nasal neurectomy for non-allergic rhinitis, and endoscopic approaches for sinonasal and orbital tumors, both extra- and intraconal. - Provides access to 70 key indicator (Accreditation Council for Graduate Medical Education Key Indicator Procedures), and surgical videos – an increase of 43% over the previous edition. - Offers outstanding visual support with 4,000 high-quality images and hundreds of quick-reference tables and boxes. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
A modern introduction to the field, Neuroimaging of the Auditory and Vestibular Systems: A Clinician’s Guide is a comprehensive resource for audiologists, neurologists, radiologists, otolaryngologists, and neurotologists. This text equips clinicians with the knowledge of imaging modalities used to evaluate conditions affecting the auditory and vestibular systems, promoting efficient and effective patient care. Clinicians will be provided with information about the anatomy and physiology of the auditory and vestibular systems, as well as, the fundamental concepts, indications, and utility of neuroimaging of this region to distinguish pathology from normal anatomy. This text also systematically describes common pathologic conditions found in the ear and lateral skull base beginning with the external ear and ending with the central nervous system. Each condition is described in terms of an overview, medical evaluation, audiological evaluation, imaging modalities and findings, and treatment considerations. Through the study of each of these anatomy-themed chapters of the auditory and vestibular system, clinicians can gain competence and confidence in differentiating pathologic conditions that may present in similar locations with similar symptoms yet have different imaging finding. The integration of transdisciplinary perspectives into the text makes this a special addition to the market. Written by a team of distinguished professionals, every chapter will include relevant and up-to-date material on the use of neuroimaging modalities to optimize auditory and vestibular healthcare, and is widely applicable to diverse clinicians in the field. The emphasis on the importance of incorporating and interpreting neuroimaging in clinical practice can enhance collaborative communication and patient care. Key Features * Anatomy-based description of common pathologic conditions * Comprehensive depiction of pathology through detailed complementary MRI and CT images * Presentation of audiological findings that correlate with clinical scenarios * Foreword written by Frank E. Musiek, PhD, CCC-A (Ret.) Transdisciplinary and multi-institutional contributions from experts in audiology, otolaryngology, neurotology, and radiology From the Foreword "Graduate students in audiology, the neurosciences, as well as residents in otolaryngology, neurology and neurosurgery and those professionals practicing in these areas will find this text informative, relevant, and useable. I can see this book becoming the “go to” resource and guide for those professionals in the clinical setting serving patients with disorders of the auditory and vestibular systems." —Frank E. Musiek, PhD, CCC-A (Ret.)
“A skilled science translator, Denworth makes decibels, teslas and brain plasticity understandable to all.”—Washington Post Lydia Denworth’s third son, Alex, was nearly two when he was identified with significant hearing loss that was likely to get worse. Denworth knew the importance of enrichment to the developing brain but had never contemplated the opposite: deprivation. How would a child’s brain grow outside the world of sound? How would he communicate? Would he learn to read and write? An acclaimed science journalist as well as a mother, Denworth made it her mission to find out, interviewing experts on language development, inventors of groundbreaking technology, Deaf leaders, and neuroscientists at the frontiers of brain plasticity research. I Can Hear You Whisper chronicles Denworth’s search for answers—and her new understanding of Deaf culture and the exquisite relationship between sound, language, and learning.
The Comprehensive Handbook of Pediatric Audiology, Second Edition is the most wide-ranging and complete work of its kind, and has become the definitive reference in the specialty area of pediatric audiology. Content areas range from typical auditory development, to identification and diagnostic processes, to medical and audiologic management of childhood hearing and ear disorders. An interdisciplinary assembly of sixty-six internationally recognized experts from the fields of audiology, speech-language pathology, education, pediatric medicine, otology, and hearing science have contributed to this second edition. Building from the success of the first edition, and aligning with the evolution of the profession, this edition expands and deepens its coverage of early identification of hearing loss, etiology and medical considerations, and hearing technologies, especially implantable devices and the measurement of outcomes resulting from intervention. Updates to the new edition include: New chapters on the measurement of outcomes resulting from intervention, preventable hearing loss, implementation of newborn hearing screening programs, and the future of implantable devices, among othersReorganization for improved sequencing of content areaSubstantially updated chapters The Comprehensive Handbook of Pediatric Audiology, Second Edition is intended for use in doctoral-level education programs in audiology or hearing science, as well as to serve as an in-depth reference source for practicing audiologists and other professionals, educators, scientists, and policy makers seeking current and definitive information on evidence-based pediatric audiology practice.