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The ATSDR toxicological profile succinctly characterizes the toxicology and adverse health effects information for the toxic substance described therein. Each peer-reviewed profile identifies and reviews the key literature that describes a substance's toxicological properties. Di(2-ethylhexyl)phthalate, commonly referred to as DEHP, is not found naturally in the environment. DEHP was widely used as a plasticizer to help make polyvinyl chloride (PVC) products soft and flexible(CPSC 2010a). Because some DEHP is retained in PVC, it is present in many common items such as wall coverings, tablecloths, floor tiles, furniture upholstery, shower curtains, garden hoses, swimming pool liners, rainwear, baby pants, dolls, toys, shoes, automobile upholstery and tops, packaging film and sheets, sheathing for wire and cable, medical tubing, and blood storage bags. It had been detected in children's products such as pacifiers at levels of up to 42% by weight (Lay and Miller 1987); however, the U.S. Congress banned children's items that contain DEHP at levels >0.1% by weight (CPSIA 2008).
This report provides information about Di (2-Ethylhexyl) Phthalate (DEHP) & the human health effects of exposure. This chemical has been found in many sites identified by the EPA for long-term Federal cleanup activities. The report includes a Public Health Statement which explains the toxicologic properties of DEHP in a nontechnical, Q&A format, & a review of the general health effects observed following exposure; a description of health effects; how the chemical can affect children; & information on its chemical & physical properties, production, use & disposal, potential for human exposure, analytical methods, & regulations & advisories.