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This volume contains monographs prepared at the eighty-fifth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which met in Geneva, Switzerland, from 17 to 26 October 2017. [Author] The toxicological monographs in this volume summarize data on the veterinary drug residues that were evaluated toxicologically by the Committee: amoxicillin, ampicillin, ethion, flumethrin, halquinol and lufenuron. [Author] Annexed to the report is a summary of the Committee’s recommendations on these and other drugs discussed at the eighty-fifth meeting, including acceptable daily intakes (ADIs), acute reference doses (ARfDs) and proposed maximum residue limits (MRLs). [Author] This volume and others in the WHO Food Additives Series contain information that is useful to those who produce and use food additives and veterinary drugs and those involved with controlling contaminants in food, government and food regulatory officers, industrial testing laboratories, toxicological laboratories and universities. [Author]
The report contains the monographs that were prepared at the eighty-eighth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which took place at the headquarters of the Food and Agriculture Organization of the United Nations (FAO) in Rome on 22–31 October 2019. [Author] These monographs summarize the data on the safety of residues in food of selected veterinary drugs reviewed by the JECFA. [Author]
The monographs contained in this volume were prepared at the eighty-eighth meeting of the Joint Food and Agriculture Organization of the United Nations (FAO)/World Health Organization (WHO) Expert Committee on Veterinary drugs (JECFA), which met at WHO headquarters in Rome, Italy, 22–31 October 2019. These monographs summarize the data on selected veterinary drugs reviewed by the Committee.
The monographs contained in this volume were prepared at the seventy-fifth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which met at FAO headquarters in Rome, Italy, on 8-17 November 2011. These monographs summarize the data on the safety of residues in food of selected veterinary drugs reviewed by the Committee.
This report represents the conclusions of a Joint FAO/WHO Expert Committee convened in 2017 to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of residues of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), including chronic dietary exposure assessment of compounds used as veterinary drugs and pesticides, assessment of the relative bioavailability and/or pharmacological activity of incurred drug residues in animal tissues, acute reference doses (ARfDs) for residues of veterinary drugs and methodological approaches and types of data for assessment of veterinary drug residues in food. Summaries follow of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: three antimicrobial agents (amoxicillin, ampicillin and halquinol), an acaricide (ethion), an antiparasitic agent (flumethrin), an insecticide (lufenuron) and an anthelminthic (monepantel). In addition, the Committee considered issues raised by the Codex Committee on Residues of Veterinary Drugs in Foods concerning sisapronil, an ectoparasiticide, and zilpaterol hydrochloride, a ß2-adrenoceptor agonist. Annexed to the report is a summary of the Committee's recommendations on these drugs, including acceptable daily intakes (ADIs), ARfDs and proposed maximum residue limits (MRLs).