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One of the most important issues, when a nanomaterial is designed, is to control the synthetic pathways to ensure the final desired product. A combination of dry and wet procedures, as well as chemical and physical methodologies, it is possible to successfully prepare new multifunctional nanomaterials, often as a result of multidisciplinary cooperation between chemists, physics, biologist, physicians, material engineers, etc. Drug delivery, environmental detection of contaminants, and many industrial applications directly rely on properties such as water solubility, permeability, cell penetration, shape control, and size of the monodispersed nanoparticle, among others. Functionalized nanomaterials play a crucial role in modern research areas because of their unique physical and chemical properties, explored in many different fields including medicine and biology, new materials, pharmacology as drug delivery systems, and in environmental analysis for sensing new contaminants, among other technical and industrial applications. For future technological applications, the rational design of these multifunctional nanomaterials is critical, and often depends on the excellent control of the organic and inorganic chemical reactions involved during production. The success of their applications relies directly on the photophysical properties created in the final material, including the emission of light or colorimetric responses, water solubility, selectivity, sensitivity, stability, etc. For example, from an analytical point of view, the detection and quantification of emerging analytes is directly dependent on the selectivity and sensitivity showed by the material in a complex media.
Rational Design of Enzyme-Nanomaterials, the new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in rational design of enzyme-nanomaterials, and includes sections on such topics as conjugation of enzymes and dextran-aldehyde polymers, improved activity of enzymes bound to titanate nanosheet, nano-layered 'stable-on-the-table' biocatalysts and nanoparticle-based enzyme sensors. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in rational design of enzyme-nanomaterials - Contains sections on such topics as conjugation of enzymes and dextran-aldehyde polymers, improved activity of enzymes bound to titanate nanosheet, nano-layered 'stable-on-the-table' biocatalysts, and nanoparticle-based enzyme sensors
Despite the fact that nanotechnology has been present for a few decades, there is a big gap between how nanotechnology is perceived and what nanotechnology can truly offer in all sectors of water. The question to be answered is 'what more can we expect from nanotechnology' in the water field? The rational nano-design starts with well-defined problem definitions, necessitates interdisciplinary approaches, involves 'think-outside-the-box', and represents the future growth point of environmental nanotechnology. However, it is still largely new to the educated public and even scientists and engineers in water fields. Therefore, it is the purpose of this book to promote the concept of rational nano-design and to demonstrate its creativity, innovation, and excitement. This book presents a series of carefully selected rationally designed nano- materials/devices/surfaces, which represent drastically different, ground-breaking, and eye-opening approaches to conventional problems to embody the concept of nano-design and to illustrate its remarkable potential to change the face of the research in water industry in the future. Each of the book contributors is world-renowned expert in the burgeoning field of rational nano-design for applications. Rational Design of Next-generation Nanomaterials and Nanodevices for Water Applications is intended for undergraduates, graduates, scientists and professionals in the fields of environmental science, material science, chemistry, and chemistry engineering. It provides coherent and good material for teaching, research, and professional reference. Contents: Introduction to rational nano-design for water applications; Rational design of smart materials/surfaces with switchable oil wettability for sustainable oil-spill cleanup; Rational design of three-dimensional macroscale porous electrodes for bioelectrochemical systems; Design of (photo)electrochemical active membranes as next-generation filtration devices; Hierarchical materials as a design concept for multifunctional membranes; Rational design of functional nanoporous materials to confine water pollutant in controlled nano-space; A next-generation forward osmosis draw solution design; Rational design of magnetic permanently-confined micelle arrays (Mag-PCMAs) materials for sustainable water and soil remediation; Rational design of an all-in-one lab-on-chip device for direct seawater desalination; Design of micro-sized microbial fuel cells as miniature energy harvesters Author: Peng Wang, King Abdullah University of Science and Technology
Zusammenfassung: This book is a compilation of carefully chosen chapters that cover the subjects of nanoscale matter, sensing, and labelling applications. It is aimed primarily at scientists and researchers who are already involved in theme-based research or who are just starting their careers. Despite the diverse nature of the topics covered, which include a range of materials in various forms and uses, the emphasis is primarily on sensing and labelling phenomena. The book begins with materials quantification in nanoscale systems by using an innovative technique like "molecular secondary ion mass spectrometry without calibration standards". Subsequently, the book features an array of materials such as inorganic semiconductor nanoscale particles, carbon dots, rare-earth oxides, polymer nanocomposites, and a few biomaterials, all of which illustrate their functionality and potential for deployment in a wide variety of sensing applications. Although the book delves into the technical aspects of fabrication workouts to some extent, the focus is predominantly on the physical principles, mechanisms, and relevance involved in sensing and labelling applications. The book covers a wide range of topics that leverage the unique properties of nanoscale materials. By carefully selecting appropriate active materials, the authors explore the detection of LPG, hazardous and explosive gases, as well as humidity sensing and hydrogen evolution. It also delves into photo-sensing and persistent photoconductivity by using nanoscale semiconductors, which are used for heavy metal sensing and UV sensing, respectively. The use of metal nanoparticles in various forms is reviewed to address issues related to water contamination, biofilm protection, and food-borne pathogens. The book also discusses surface plasmon resonance, starting with its basic principles and expanding to its relevance in a broader perspective, with a greater focus on applied biosensing. Nanoscale ferrites and magnetic systems are explored with an emphasis on magnetic sensing and actuation. Lastly, the book explores the use of rare-earth-based nanosystems, highlighting persistent luminescence and up/down-converted transitions, which have unprecedented applications in bioimaging and biolabeling. Every effort has been made to strike a balance between the observed phenomena in the emerging areas of sensing applications and suitable theoretical treatments there in.
After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation. FEATURES Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.
Understanding the molecular mechanisms of cancer is the key for transforming cancer medicine. A substantial proportion of human genes show alternative splicing and mis-regulation of Pre-mRNA splicing is seen in several cancers.This book further investigates these matters. The first few chapters provide an update on the role of genomics in understanding alternative splicing, and targets in cancer pathogenesis. Advances and prospects in applications of nanotechnology for cancer prevention, detection and treatment are a promising field of research. The subsequent chapters provide insights on how nanotechnology-based therapeutics are moving towards revolutionizing cancer and infectious disease treatment by minimizing toxicity and facilitating targeted delivery of drugs. Technical topics discussed in the book include: • Alternative splicing and cancer• Cancer imaging• Nanomaterials in infectious diseases• Nanomedicine in oxidative stress and cancer• Nanoparticle based drug delivery systems
This book is the first in a series compiling highly cited articles in nanomedicine recently. The series is edited by Lajos P. Balogh, a prominent nanotechnology researcher and journal editor. The first book content is about nanotechnology in cancer research. It also includes a wide variety of must-know topics that will appeal to any researcher involved in nanomedicine, macromolecular science, cancer therapy, and drug delivery research. These 31 articles collected here have already acquired more than 3500 citations (i.e., over a hundred on average), highlighting the importance and recognized professional interest of the scientists working in this field.
Nanomaterials for Environmental Applications offers a comprehensive review of the latest advances in nanomaterials-based technologies for the treatment of emerging contaminants in wastewater. It describes the latest developments in the synthesis protocols, including the synthesis of different kinds of nanostructure materials using various physical and chemical methods. Features Discusses the synthesis and characterization of important nanomaterials such as carbon nanostructures, metal and metal oxide nanostructures, polymer nanostructures, and smart 1D-–3D nanomaterials Presents the latest techniques used in the characterization of nanomaterials Covers environmental applications including the remediation of pollutants in wastewater and water purification and disinfection Examines the sources, fate, transport, and ecotoxicology of nanomaterials in the environment. Aimed at researchers and industry professionals, this work will be of interest to chemical, environmental, and materials engineers concerned with the application of advanced materials for environmental and water remediation. Mohamed Abou El-Fetouh Barakat is a Professor of Environmental Sciences at both King Abdulaziz University (KAU)- Saudi Arabia, and Central Metallurgical R&D Institute (CMRDI)- Egypt. He is highly qualified in the fields of industrial waste management and pollution control as well as catalysis and nanotechnology. His experience includes academic research works in Japan, Germany, the United States and Saudi Arabia, as well as initiating and leading industrial research projects in Egypt jointly with the United States. Rajeev Kumar is an Associate Professor in the Environmental Science Department, King Abdulaziz University, Jeddah, Saudi Arabia. His research activities are in the areas of wastewater treatment and materials science. He studies the adsorption and photocatalytic properties of nanomaterials for the removal of contaminants from wastewater.
Modern Inorganic Synthetic Chemistry, Second Edition captures, in five distinct sections, the latest advancements in inorganic synthetic chemistry, providing materials chemists, chemical engineers, and materials scientists with a valuable reference source to help them advance their research efforts and achieve breakthroughs. Section one includes six chapters centering on synthetic chemistry under specific conditions, such as high-temperature, low-temperature and cryogenic, hydrothermal and solvothermal, high-pressure, photochemical and fusion conditions. Section two focuses on the synthesis and related chemistry problems of highly distinct categories of inorganic compounds, including superheavy elements, coordination compounds and coordination polymers, cluster compounds, organometallic compounds, inorganic polymers, and nonstoichiometric compounds. Section three elaborates on the synthetic chemistry of five important classes of inorganic functional materials, namely, ordered porous materials, carbon materials, advanced ceramic materials, host-guest materials, and hierarchically structured materials. Section four consists of four chapters where the synthesis of functional inorganic aggregates is discussed, giving special attention to the growth of single crystals, assembly of nanomaterials, and preparation of amorphous materials and membranes. The new edition's biggest highlight is Section five where the frontier in inorganic synthetic chemistry is reviewed by focusing on biomimetic synthesis and rationally designed synthesis. - Focuses on the chemistry of inorganic synthesis, assembly, and organization of wide-ranging inorganic systems - Covers all major methodologies of inorganic synthesis - Provides state-of-the-art synthetic methods - Includes real examples in the organization of complex inorganic functional materials - Contains more than 4000 references that are all highly reflective of the latest advancement in inorganic synthetic chemistry - Presents a comprehensive coverage of the key issues involved in modern inorganic synthetic chemistry as written by experts in the field