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This textbook describes the study of radiation, covering the basic concepts and their advanced applications, and highlights the handling of radioisotopes and radiation measurements using various instruments. The book also focuses on the effects and up-to-date applications of radiation on biological systems and their use in diagnosing and treating various diseases. Chapters provide an easy understanding of the subject matter with the help of self-explanatory, well-illustrated figures and easy-to-grasp language. “Tools and Techniques in Radiation Biophysics” is designed for undergraduate and post-graduate studying radiation Biophysics as one of the major courses in medical physics, nuclear medicine, biophysics, and other applied sciences. The multi-disciplinary approach of this book facilitates learning and a deep understanding of the concepts and helps the readers develop an interest in the subject so that they can pursue their careers efficiently in this field. Researchers and lecturers will value this book to enhance their knowledge and clarify queries.
This book describes the state of the art across the broad range of spectroscopic techniques used in the study of biological systems. It reviews some of the latest advances achieved in the application of these techniques in the analysis and characterization of small and large biological compounds, covering topics such as VUV/UV and UV-visible spectroscopies, fluorescence spectroscopy, IR and Raman techniques, dynamic light scattering (DLS), circular dichroism (CD/SR-CD), pulsed electron paramagnetic resonance techniques, Mössbauer spectroscopy, nuclear magnetic resonance, X-ray methods and electron and ion impact spectroscopies. The second part of the book focuses on modelling methods and illustrates how these tools have been used and integrated with other experimental and theoretical techniques including also electron transfer processes and fast kinetics methods. The book will benefit students, researchers and professionals working with these techniques to understand the fundamental mechanisms of biological systems.
Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.
In October 1982, a small international symposium was held at the Gesellschaft fUr Strahlen- und Umweltforschung mbH (GSF) in Munich as a satellite meeting of the IX International Conference on Analytical Cytology. The symposium focussed on cytometric approaches to biological dosimetry, and was, to the best of our knowledge, the first meeting on this subject ever held. There was strong encouragement from the 75 attendees and from others to publish a proceedings of the symposium. Hence this book, containing 30 of the 36 presentations, has been assembled. Dosimetry, the accurate and systematic determination of doses, usually refers to grams of substance administered or rads of ionization or some such measure of exposure of a patient, a victim or an experimental system. The term also can be used to describe the quantity of an ultimate, active agent as delivered to the appropriate target material within a biological system. Thus, for mutagens, one can speak of DNA dosimetry, meaning the number of adducts produced in the DNA of target cells such as bone-mar row stem cells or spermatogonia.
The papers collected in this hugely useful volume cover the principle physical and biological aspects of radiation therapy and in addition, address practical clinical considerations in the planning and delivering of that therapy. The importance of the assessment of uncertainties is emphasized. Topics include an overview of the physics of the interactions of radiation with matter and the definition of the goals and the design of radiation therapy approaches.
The first of its kind, Introduction to Biophysical Methods for Protein and Nucleic Acid Research serves as a text for the experienced researcher and student requiring an introduction to the field. Each chapter presents a description of the physical basis of the method, the type of information that may be obtained with the method, how data should be analyzed and interpreted and, where appropriate, practical tips about procedures and equipment.Key Features* Modern Use of Mass Spectroscopy* NMR Spectroscopy* Molecular Modeling and Graphics* Macintosh and DOS/Windows 3.x disks
Details technology associated with radiation oncology, emphasizing design of all equipment allied with radiation treatment. Describes procedures required to implement equipment in clinical service, covering needs assessment, purchase, acceptance, and commissioning, and explains quality assurance issues. Also addresses less common and evolving technologies. For medical physicists and radiation oncologists, as well as radiation therapists, dosimetrists, and engineering technologists. Includes bandw medical images and photos of equipment. Paper edition (unseen), $145.95. Annotation copyrighted by Book News, Inc., Portland, OR
This newly revised and updated edition of Radiation Biophysics provides an in-depth description of the physics and chemistry of radiation and its effects on biological systems. Coverage begins with fundamental concepts of the physics of radiation and radioactivity, then progresses through the chemistry and biology of the interaction of radiation with living systems. The Second Edition of this highly praised text includes major revisions which reflect the rapid advances in the field. New material covers recent developments in the fields of carcinogenesis, DNA repair, molecular genetics, and the molecular biology of oncogenes and tumor suppressor genes. The book also includes extensive discussion of the practical impact of radiation on everyday life. - Covers the fundamentals of radiation physics in a manner that is understandable to students and professionals with a limited physics background - Includes problem sets and exercises to aid both teachers and students - Discusses radioactivity, internally deposited radionuclides, and dosimetry - Analyzes the risks for occupational and non-occupational workers exposed to radiation sources
This book provides a comprehensive yet accessible overview of all relevant topics in the field of radiation protection (health physics). The text is organized to introduce the reader to basic principles of radiation emission and propagation, to review current knowledge and historical aspects of the biological effects of radiation, and to cover important operational topics such as radiation shielding and dosimetry. The author’s website contains materials for instructors including PowerPoint slides for lectures and worked-out solutions to end-of-chapter exercises. The book serves as an essential handbook for practicing health physics professionals.