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This unique publication explores diverse themes relating to thrombosis and embolism, from basic research at cell and molecular level to the actual care, prevention, and treatment of diverse categories of patients suffering from such diseases. Chapters cover a variety of topics including thrombosis and embolism in surgical patients, cancer patients, pregnant women and children and adolescents, as well as treatment of the conditions by traditional anticoagulants, novel oral anticoagulants, thrombolytic therapy, endovascular treatment and embolectomy. Readers may explore cutting edge research, recommendations from major societies, contemporary guidelines, areas of controversy and directions for ongoing and future research. The book features comprehensive information ranging from molecular mechanisms of diseases to the clinical features, diagnosis, and therapeutic regimens for treating a variety of clinical conditions. It has a broad appeal to scientists and research students as well as busy clinicians engaged in patient care, who will all find something important and useful amongst these carefully selected chapters.
The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.
This Guideline was developed by the National Health and Medical Research Council's National Institute of Clinical Studies in collaboration with a 16 member multidisciplinary committee of experts. This Guideline provides evidence-based recommendations for the prevention of venous thromboembolism (blood clots), in adult surgical and medical patients and pregnant women admitted to Australian metropolitan, regional and rural hospitals.
Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides
Designed for everyday use, primarily in the hospital setting, Thrombosis in Clinical Practice is a practical clinical reference to the management of thrombosis. The text provides a concise guide to the latest drugs and their applications and reviews appropriate therapeutic strategies for each of the most commonly-encountered clinical scenarios. Numerous flowcharts and checklists support and enhance the text, assisting the reader with case assessment and formulation of treatment plans. Copiously illustrated with tables, graphs, and charts, the book explains fundamental principles of etiology and mechanisms of drug action and includes the latest information on new agents and on-going trials.
With the aim of improving the prevention, diagnosis and treatment of venous thromboembolism (VTE) in day-to-day clinical practices, this reference provides a wide range of perspectives from international specialists on research concerning this disorder, exploring subjects have an impact in the field, including VTE and pregnancy, hypercoagulable sta
This third edition expands upon the role of anticoagulants in clinical practice. In addition, it summarizes new developments in the field and provides evidence-based guidelines for the use of anticoagulants in routine day-to-day practice. The Handbook of Thromboprophylaxis Third Edition is a key resource for all physicians with an interest in thromboprophylaxis.
Fully updated to reflect current evidence based practice Deep Vein Thrombosis and Pulmonary Embolism: A guide for Practitioners covers the pathology and common problems in clinical medicine and general practice related to venous thrombosis. The new edition has details of the theory and practice of traditional drugs and the use of non-Vitamin K antagonist oral anticoagulants (NOACs) and overall the book will enable the practitioner to manage their patients with confidence Contents include: Introduction What is deep vein thrombosis and pulmonary embolism and why are they important? Who is at risk of these conditions and why? Recognising and confirming DVT and PE What have we got to treat these conditions? Clinical practice of anticoagulation Heparin and LMWH Warfarin Non-vitamin K antagonist anticoagulants (NOACs) What happens if something goes wrong? – Haemorrhage References Answers to Consolidation notes and Case Studies
In the realm of medical practice, the word “embolism” has many implications to many people, with most providers instinctively placing this word within an inherently negative context. Derived from the Greek word, ἐμβολισμός, this term most literally means “interposition.” Yet, regardless of how benign this etymological derivation may appear, the clinical context is quite the opposite—a symbol of much dreaded morbidity and mortality. Whether the embolus consists of a blood clot, a fat globule, a bubble of gas, amniotic fluid, or even an iatrogenic or traumatic foreign body, the unfavorable connotations persist even if the patient has few or no associated symptoms and requires no intervention.The primary goal of this book is to provide the reader with an overview of the most common types of embolic phenomena encountered in clinical practice, including some of the key related diagnostic and therapeutic considerations. Among chapters featured in the current collection are important contributions in the areas of pulmonary embolism, fat embolism, embolic complications of non-malignant cardiac tumors, acute arterial embolism of the lower extremity, thrombophilia in pregnancy, bullet and shrapnel embolization, coronary artery embolization, as well as a comprehensive review of venous interventions utilized in the management of thromboembolic disorders. When measured in terms of both human and financial costs, broadly defined “embolic phenomena” have tremendous impact on healthcare systems and societies around the globe. Through this academic effort of both our editorial team and individual chapter authors, we hope to provide the reader with valuable insight into the gravity of the collective problem. Among key takeaway messages of this book is that diagnostic relativity and uncertainty continue to prevail in the realm of “embolic diseases.” Consequently, much more progress is required before we are able to declare success.
A must have resource for clinicians and investigators interested in pulmonary embolism and deep venous thrombosis Highly illustrated with numerous tables and graphs alongside clear concise text Includes chapters addressing pulmonary embolism (PE) and deep venous thrombosis (DVT) in relation to diseases and disorders such as; chronic heart failure, cancer, diabetes, stroke, chronic obstructive pulmonary disease (COPD) and many more Discusses the role the different tools offered in imaging for PE, including echocardiography, multidetector computed tomography (CT), single photon emission computed tomography (SPECT), ventilation-perfusion (V-Q) imaging, dual energy CT, and magnetic resonance angiography Contains 29 new chapters and includes new content on epidemiology of deep venous thrombosis; use of the new anticoagulants (dabigatran, rivaroxaban, and apixaban) for DVT and PE; indications and results with thrombolytic therapy and with vena cava filters; and information and indications for invasive mechanical thrombectomy and thrombolysis Written by an internationally recognized and respected expert in the field