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In this book, prominent Russian scientist Yuriy I. Khavkin shows that the droplet sizes in swirl atomizers depend only on the specific energy of the liquid drops and on viscosity. The new theory based only on two parameters is shown to be far simpler and in better agreement with experimental data than any previous presentations. The following topics are included in the book: · The solution of the Navier-Stokes equation for a liquid rotating flow · Atomizers for gas turbine combustion chambers · Atomizers for high capacity steam boilers · Atomizers for liquid-propellant rocket engines · Quality of liquid atomization by non-swirl atomizers · A unique table of experimental data of 232 atomizers, enables the reader to find an atomizer with the flow rate from 5 kg/h to 15,000 kg/h Readers will also learn: · To create an atomizer with the given mean droplet size · To create an atomizer with the given droplet size distribution · To create an atomizer with the given limits of flow rate control. The book is intended for the design engineer, as well as the theoretical scientist.
Atomization and sprays are used in a wide range of industries: mechanical, chemical, aerospace, and civil engineering; material science and metallurgy; food; pharmaceutical, forestry, environmental protection; medicine; agriculture; meteorology and others. Some specific applications are spray combustion in furnaces, gas turbines and rockets, spray drying and cooling, air conditioning, powdered metallurgy, spray painting and coating, inhalation therapy, and many others. The Handbook of Atomization and Sprays will bring together the fundamental and applied material from all fields into one comprehensive source. Subject areas included in the reference are droplets, theoretical models and numerical simulations, phase Doppler particle analysis, applications, devices and more.
This book reports on topics at the interface between manufacturing, mechanical and chemical engineering. It gives a special emphasis to CAD/CAE systems, information management systems, advanced numerical simulation methods and computational modeling techniques, and their use in product design, industrial process optimization and in the study of the properties of solids, structures and fluids. Control theory, ICT for engineering education as well as ecological design and food technologies are also among the topics discussed in the book. Based on the International Conference on Design, Simulation, Manufacturing: The Innovation Exchange (DSMIE-2018), held on June 12-15, 2018, in Sumy, Ukraine, the book provides academics and professionals with a timely overview and extensive information on trends and technologies behind current and future developments of Industry 4.0, innovative design and renewable energy generation.
In the last decade, there has been an influx in the development of new technologies for deep space exploration. Countries all around the world are investing in resources to create advanced energetic materials and propulsion systems for their aerospace initiatives. Energetic Materials Research, Applications, and New Technologies is an essential reference source of the latest research in aerospace engineering and its application in space exploration. Featuring comprehensive coverage across a range of related topics, such as molecular dynamics, rocket engine models, propellants and explosives, and quantum chemistry calculations, this book is an ideal reference source for academicians, researchers, advanced-level students, and technology developers seeking innovative research in aerospace engineering.
This book reports on topics at the interface between mechanical and chemical engineering, emphasizing design, simulation, and manufacturing. Specifically, it covers recent developments in the mechanics of solids and structures, numerical simulation of coupled problems, including fatigue, fluid behavior, particle movement, pressure distribution. Further, it reports on developments in chemical process technology, heat and mass transfer, energy-efficient technologies, and industrial ecology. Based on the 4th International Conference on Design, Simulation, Manufacturing: The Innovation Exchange (DSMIE-2021), held on June 8-11, 2021, in Lviv, Ukraine, this second volume of a 2-volume set provides academics and professionals with extensive information on trends, technologies, challenges and practice-oriented experience in the above-mentioned areas.
This book presents the select proceedings of the International Conference on Thermofluids and Manufacturing Science (ICTMS 2022). Some of the topics covered include Heat transfer, fluid dynamics, multiphase flow, flow diagnostics using artificial neural network, aerodynamics, high-speed flows, sustainable energy technology, propulsion and emissions, Eco-friendly manufacturing, Coating Techniques and Supply chain management etc. Given the scope, the book will be highly useful for researchers and professionals interested in mechanical, production or aerospace engineering
This forward-looking book focuses on the recent advances in nanomedicine and drug delivery. It outlines the extraordinary new tools that have become available in nanomedicine and presents an integrated set of perspectives that describe where we are now and where we should be headed to put nanomedicine devices into applications as quickly as possible, while also considering the possible dangers of nanomedicine. The book considers the full range of nanomedicinal applications that employ molecular nanotechnology inside the human body, from the perspective of a future practitioner in an era of widely available nanomedicine. Written by some of the most innnovative minds in medicine and engineering, this unique volume will help professionals understand cutting-edge and futuristic areas of research that can have tremendous payoff in terms of improving human health. Readers will find insightful discussions of nanostructured intelligent materials and devices that are considered technically feasible and which have a high potential to produce advances in medicine in the near future. Topics include: Health benefits of phytochemicals and the application of colloidal delivery systems Study of non-covalent attachment of recombinant targeting proteins to polymer-modified Adenoviral gene delivery vectors The role of nanoparticles as adjuvants for mucosal vaccine delivery Poly(amido-amine)s as delivery styems for biologically active substances Antimicrobial activity of silver nanoparticles Nanomedicine in the use of cancer treatment Dendrimers, capsules based on lipid vesicles for drug delivery Many other recent achievements
Providing a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology – a leading platform to deliver poorly water soluble drugs, a major hurdle in today’s pharmaceutical industry. • Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems • Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property, and regulatory considerations • Has an appendix with structure and property information for polymers commonly used in drug development and with marketed drugs developed using the amorphous sold dispersion approach • Addresses global regulatory issues including USA regulations, ICH guidelines, and patent concerns around the world
Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more. - Written and edited by an international team of leading experts with experience and knowledge across industry, academia, and regulatory settings - Includes new chapters covering the pharmaceutical applications of surface phenomenon, predictive biopharmaceutics and pharmacokinetics, the development of formulations for drug discovery support, and much more - Presents new case studies throughout, and a section completely devoted to regulatory aspects, including global product regulation and international perspectives