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New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
This heavily revised second edition comprehensively reviews the use of optical coherence tomography (OCT) in cardiovascular practice. It provides detailed guidance on how to properly interpret OCT images and successfully utilise it in daily clinical practice Chapters cover the development and physics associated with OCT, relevant interpretation skills, OCT imaging artifacts, plaque erosion, bioabsorbable stent, the detection of vulnerable plaque, and the use of OCT imaging in unison with other modalities such as phase contrast imaging (PCI). Areas of potential future development are also covered Cardiovascular OCT Imaging enables interventional cardiologists and cardiologists to quickly become both familiar and develop a detailed understanding of this technology to improve patient care and treatment outcome. It is a valuable reference for all practising and trainee medical professionals in cardiology, and in particular those who specialize in interventional cardiology.
Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students.Key Features* The most comprehensive book available on this topic* Clear, concise, and complete coverage of all important aspects of cardiovascular physiology/pathophysiology* Completely updated version of the foremost reference on cardiovascular science, including new information on pathophysiology and electrophysiology* Useful tool in bridging the gap between basic science, pathophysiology, and clinical cardiology
Acute Coronary Syndromes—a Companion to Braunwald’s Heart Disease—covers the state-of-the-art scientific and clinical information you need to rapidly evaluate and manage acute coronary syndromes. Dr. Pierre Theroux and his team of expert contributors present advances in diagnostic and imaging techniques such as biomarkers, nuclear cardiology, echocardiography, and multislice CT; secondary prevention; and new antiplatelet, anti-ischemic, and gene therapies. Tap into the most definitive knowledge available from one of the leading experts in the field and a stellar cast of contributors. Understand the special considerations for the care of acute coronary syndromes in the emergency department and the coronary care unit. Effectively handle the treatment of special populations and chronic patients thanks to coverage of these challenges See techniques and procedures in greater detail and clarity through the all-new full-color design. Approach treatment with a global perspective from the new section on Population-Based Perspective that discusses the INTERHEART study, insights from the REACH registry, lessons learned from European registries, and ACS in North America. Gain a comprehensive understanding of ACS through coverage of pathophysiology, molecular mechanisms, the role of the immune system, and brand-new chapters on cell necrosis and cell regeneration and pharmacogenetics in the section on Disease-Based Perspectives. Integrate the latest testing and treatment techniques into your practice thanks to new chapters on biomarkers in acute ischemic heart disease; the role of noninvasive testing in prognostic risk stratification; the culprit lesions and patient at risk; non-responsiveness to antiplatelet therapy; bleeding in the acute coronary syndromes; and the refractory patient.
This textbook is a readily accessible educational tool for all fellows undertaking subspecialty training in interventional cardiology, while also serving as a refresher to early career interventional cardiologists. The key objective is to equip the reader with an evidence-based expert-led resource focussed primarily on pre-procedural planning, peri-procedural decision-making, and the salient technical aspects of performing safe and effective coronary intervention, the intention being to support the therapeutic decision-making process in the emergency room, coronary care unit or cath lab in order to optimize patient outcome. The Interventional Cardiology Training Manual provides readers with a step-by-step guide to the basic principles underpinning coronary intervention and facilitates rapid access to best practice from the experts, presented in a pragmatic, digestible and concise format. Uniquely, each chapter has been written in a heart center-specific manner, affording the reader an opportunity to learn how individual institutions perform a specific procedure, which algorithms and guidelines they follow and what evidence they draw on to instigate the best possible care for their patients.
Neurosonology is non-invasive, portable, and has excellent temporal resolution, making it a valuable and increasingly popular tool for the diagnosis and monitoring of neurological conditions when compared to other imaging techniques. This guide looks beyond the use of neurovascular ultrasound in stroke to encompass a wide range of other neurological diseases and emergencies. It offers a practical approach to the examination of patients, interpretation of ultrasound studies, and the application of neurosonology to the development of management and treatment strategies. Each chapter incorporates a thorough and clear procedural methodology alongside scanning tips for trainees; this step-by-step approach is further enhanced by example images and focused diagnostic questions. Authored and edited by international experts, this practical manual of neurosonology is an invaluable resource for neurologists, neurosurgeons, intensivists, radiologists, and ultrasonographers.
Since publication of the First Edition, advances in the diagnosis and prevention and treatment strategies of the vulnerable plaque have necessitated this greatly expanded second edition. With several new chapters covering mainly diagnostic and treatment options, The Handbook of the Vulnerable Plaque will remain the benchmark text for all interventi
This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.
Coronary artery atherosclerosis is the most common cardiac pathology, which is the primary cause of cardiac mortality. Coronary artery stenosis usually involves the proximal portion of the larger epicardial coronary arteries, but diffuse coronary artery disease is also not rare. Most of the patients with/without several comorbidities have asymptomatic atherosclerotic lesions in the coronary territory, and hence early assessment of coronary artery pathology is of utmost importance. Since early surgical intervention is superior to percutaneous interventions, coronary artery bypass grafting is the first choice for the treatment of coronary artery disease. Coronary revascularization can be performed with different approaches according to the patients risk factors. Preventive treatment of coronary artery disease should be the basic strategy for a healthy system.