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This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.
By the year 2000 half of the people in the United States were over the age of 50. By 2030, 70 million elderly will account for 20% of the U.S. population. The percentage of the population with Alzheimer’s disease is significantly on the rise and by 2025 there will be a 45% increase in developed countries and a 215% increase in developing countries. Aging populations face many other issues involving cognitive decline. Building an Ageless Mind offers practical solutions, including specific directives to assist individuals in changing the course of cognitive decline as a result of aging and disease. The brain, our ability to think, and our self-concept are so very important to individual lives, and the desire to maintain robust cognitive function is the ultimate goal for anyone concerned about the aging mind. Here, Dr. William J. Tippett helps readers understand the basics of how the brain works, and explains why engaging in certain exercises may be helpful. He gives people the tools to maintain, combat, and understand good brain health. He also examines one of the most profound brain aging related illnesses of our time, Alzheimer’s disease, and provides detailed information on how this disease affects the individual, as well as ways to protect against it and to alter its course even if it’s been diagnosed. Lifestyle strategies to promote brain health are also offered throughout. Readers will be fascinated by the way the brain functions and ages, and the many methods available to everyone to maintain better brain health as they age.
Here's comprehensive, in-depth coverage of the rapidly expanding field of non-invasive vascular diagnosis. Noted experts in vascular surgery, interventional radiology, cardiology, and vascular medicine explore the best approaches for vascular imaging of cerebrovascular disease, peripheral atherosclerotic occlusive disease, intra-abdominal occlusive disease, venous disorders, and aneurysms. They describe all of today's imaging modalities and their applications for diagnosis as well as their increasingly important intraoperative and interventional roles. The book is organized into three parts. The first part covers some fundamental issues related to the vascular laboratory and principles of vascular diagnosis. The second part has five sections concerned with imaging the various regions of the body. The third part contains a collection of miscellaneous topics such as coding and reimbursement and database maintenance.
Neurology and psychology.
Brain-Body-Mind in the Nebulous Cartesian System: A Holistic Approach by Oscillations is a research monograph, with didactical features, on the mechanisms of the mind, encompassing a wide spectrum of results and analyses. The book should appeal to scientists and graduate students in the fields of neuroscience, neurology, psychiatry, physiology, psychology, physics and philosophy. Its goals are the development of an empirical-analytical construct, denoted as “Reasonings to Approach the Mind”, and the comprehension of 20 principles for understanding the mind. This book amalgamates results from work on the brain, vegetative system, brains in the evolution of species, the maturing brain, dynamic memory, emotional processes, and cognitive impairment in neuro-psychiatric disorders (Alzheimer, Schizophrenia, Bipolar disorders). The findings are comparatively evaluated within the framework of brain oscillations and neurotransmitters. Further, a holistic approach links the brain to the cardiovascular system and overall myogenic coordination of the vegetative system. The results emphasize that EEG oscillations, ultraslow oscillations, and neurotransmitters are quasi-invariant building blocks in brain-body-mind function and also during the evolution of species: The temporal domain is where the importance of research on neural oscillators is indispensable. The core, holistic concept that emerges is that the brain, spinal cord, overall myogenic system, brain-body-oscillations, and neurotransmitters form a functional syncytium. Accordingly, the concept of “Syncytium Brain-Body-Mind” replaces the concept of “Mind”. P>