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All types of wounds can compromise an individual's wellbeing, self-image, working capacity, and independence. These financial, social, and physical implications suggest that good wound management is necessary not only for the individual, but also for the community. The science of wound healing is advancing rapidly, particularly as a result of new therapeutic approaches such as laser, skin substitutes, gene therapy, stem cell therapy and platelet rich plasma (PRP). PRP is a storage vehicle of growth factors, which are known to influence bone and soft tissue regeneration. Among the most important advantages of PRP is that it is an autologous product and thus the risk for disease transmission or immunogenic reaction can be eliminated.
This book details the uses of platelet-rich plasma (PRP) techniques for dermatologic purposes and describes the techniques and protocols for its application in clinical practice. Concise and practical, this reference covers not only the procedural steps in collecting PRP from a patient, but also applications in wound healing, hair loss, skin rejuvenation, scarring, and face and body augmentation. It addresses the issues that are caused by fad procedures, such as the "Vampire Facelift," and emphasizes the importance of reliable information in these cases. Chapters are supplemented with multimedia including high-quality images, illustrations, and an instructional video. Platelet-Rich Plasma in Dermatologic Practice is written for clinicians in practice looking to offer alternatives to more invasive aesthetic surgery techniques.
Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.
Platelet rich plasma therapy uses a patient's own platelets to encourage and accelerate healing in a variety of tissues. With the growing popularity of using platelet rich plasma for aesthetic procedures, the need for a book that ties together all of the current literature in one place has become more pressing. This book fills in that gap as a comprehensive guide that covers history, basic science and clinical utility of platelet rich plasma with its uses in hair restoration, facial rejuvenation, and some wound healing. It includes the latest studies/literature from peer reviewed journals and clinical, anecdotal experience. Chapters provide an extensive look at how to describe the mechanism of action of platelet rich plasma (PRP) in the skin and hair; how to identify the difference between PRP, platelet rich fibrin, and stem cells; and identify the various PRP preparation systems and how to calculate dosing. Aesthetic Clinician's Guide to Platelet Rich Plasma is written especially for the aesthetic clinician, whether dermatologist or plastic surgeon. This book will find utility across specialties and with it's extensive coverage it is a vital reference.
This book offers a comprehensive overview of the use of platelet rich plasma (PRP), typically by injection, and its usage across medical disciplines. This multi-authored, multi-institutional, and multi-specialty based text is designed to guide health care providers in the varied uses of PRP -- starting from its history and preparation and moving through a variety of disciplines to illustrate how PRP can help healing. Clinical Applications of Platelet Rich Plasma in Medicine is divided into three sections: The first gives an overview of the basic science of PRP; the second provides a detailed overview of the clinical indications of PRP; and the third section discusses potential complications in conjunction with relevant case studies. It will feature a wealth of images and diagrams to illustrate best practices in using PRP. Written to be used by oral and maxillofacial surgeons, plastic surgeons, cosmetic surgeons, otolaryngologists, dentists, orthopedic surgeons, and general surgeons to name a few, this book will provide an evidence-based approach to using PRP in practice. The editors have extensive academic experience and have authored multiple scientific publications, while the contributions included in the text have been written by experts and leaders in the fields touched upon in the book.
Choose the best possible skin and wound care products to support your patients’ skin health and wound healing, with the invaluable Product Guide to Skin and Wound Care, 8th Edition. Listing 294 products in alphabetical order, this handy product guide for wound care practitioners across all practice settings offers detailed information—sizes, action, indications, contraindications, application, and removal information—so that your choices stay informed and accurate.
"Regenerating damaged organs and tissues, an act that once was considered magic, is currently entrusted to the surgeons who have allowed us to move from replacement and reconstructive plastic surgery to regenerative plastic surgery, through autologous and allogeneic cell-based therapies and growth factors. The enthusiasm for regenerative plastic surgery and for the treatment of some pathologies addressed by it, such as breast reconstruction, hemifacial atrophy, burns, scars, and aesthetic improvements such as breast and buttock augmentation, face rejuvenation and hair regrowth, has led the author, Professor Pietro Gentile, to rigorously investigate the possible new minimally invasive strategies based on adipose-derived stem cells, human follicle stem cells and growth factors contained in platelet-rich plasma. This book reports on the latest knowledge regarding the treatment of soft and bone tissue defects. Therefore, the goal of this text is to introduce and definitively establish this new and interesting field of plastic surgery, called regenerative plastic surgery"--
Wound healing and its treatment are subjects that have been discussed for centuries in the medical literature. Wounds are everywhere, occurring in the young and elderly and in hospital and at home, and affect patients in every clinical specialty around the world. There are many publications on wound healing, but this book intends to give an overview of its current perspectives so as to be useful to practice care in wound healing and to improve the quality of life. It is considered that this book will be useful for clinicians who are interested in wound care.
Plasma can be defined as the extracellular matrix of blood cells. Plasma components, their role in human health risk evaluation, and their functional and clinical analyses are covered in this book. Furthermore, physical plasma-ionized gas is one of the four fundamental states of matter. This homonym has begun to emerge because it can interact with living systems. The physical plasma biomedical applications are reviewed in drug delivery and wound healing medical applications. This approach revolutionizes the therapeutic approaches in medicine and may open up new concepts and clinical applications. The book is an essential source for researchers in the field and provides a platform for different professions.
Over the recent years, biotechnology has become responsible for explaining interactions of biological tools and processes so that many scientists in the life sciences from agronomy to medicine are engaged in biotechnological research. This book contains an overview focusing on the research area of molecular biology, molecular aspects of biotechnology, synthetic biology and agricultural applications in relevant approaches. The book deals with basic issues and some of the recent developments in biotechnological applications. Particular emphasis is devoted to both theoretical and experimental aspect of modern biotechnology. The primary target audience for the book includes students, researchers, biologists, chemists, chemical engineers and professionals who are interested in associated areas. The book is written by international scientists with expertise in chemistry, protein biochemistry, enzymology, molecular biology and genetics, many of which are active in biochemical and biomedical research. We hope that the book will enhance the knowledge of scientists in the complexities of some biotechnological approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications.