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The Theory of Endobiogeny Volume 1: Global Systems Thinking and Biological Modeling for Clinical Medicine offers researchers and clinicians a detailed introduction to the theory of Endobiogeny. The book presents a new approach to medicine that is at once scientific and humanistic, quantitative, and qualitative. The philosophical and experimental basis of a global complex systems approach to physiology is presented along with a mathematical approach to modeling the dynamism of the terrain. The importance of the history and physical examination are renewed as a source of "big data readily available to clinicians for greater insight into the patient's state. Expansion of the therapeutic compendium is proposed based on a rational, clinical approach correlated to mathematical indicators of the physiologic state. What is proposed in this work is a fundamental shift in scientific thinking with a resulting expansion of the boundaries of clinical medicine for the 21st century and beyond. - Extends systems biology from the cellular to the integrative physiologic level - Moves the functional medicine approach to a higher level of integration and true global systems thinking - Presents mathematical tools and proofs of formulas related to the biology of functions: a biological modeling system based on the theory of endobiogeny. The biology of functions has assisted clinicians in conceptualizing, treating, and objectively monitoring the longitudinal effects of treatment through the evolution of the patient's unique phenotypic expression of terrain
The Theory of Endobiogeny Volume 4: Bedside Handbook concisely presents core elements of the theory and practice of clinical Endobiogeny. It is an essential reference for Endobiogenists and for integrative medicine practitioners looking to expand their practice. Signs, symptoms and biology of function indexes are correlated to each other according to principles of integrative endocrinology and physiology. Over 20 common illnesses are succinctly summarized to be read in under 10 minutes conveying the essence of neuroendocrine causes, mechanisms and effects, followed by prioritization of Endobiogenic treatments based on 40+ years of clinical experience. Finally, for exemplary prescriptions, alternate plants are proposed based on the context of the specific illness. A succinct materia medica summarizes the essence and key role of nearly 80 medicinal plants used in clinical Endobiogeny, offering new insights for experienced prescribers and clear guidance for those new to the usage of medicinal plants. The Theory of Endobiogeny Volume 4 provides clinicians and researchers with a concise handbook covering the application of Endobiogeny in current clinical practice. - Quick reference for over 20 common illnesses with suggested Endobiogenic treatments - Identification of key biology of functions indexes, signs and symptoms for each disorder - Materia medica with essence and summary of nearly 80 medicinal plants plus trace minerals - Endobiogenic diets and lifestyle recommendations
The Theory of Endobiogeny Volume 2: Foundational Concepts for Treatments of Common Clinical Conditions addresses the core elements of the adaptation response to stressors: autonomic nervous system (ANS), corticotropic axis, immunity and digestive tract function. The volume is oriented for clinical practice, offering clear discussions on treating the root cause of numerous common disorders, and symptomatically addressing the destabilizing factor in a vast number of disorders ranging from depression to irritable bowel, and from migraines to insomnia called spasmophilia. - Extends the concepts of global systems integrative physiology to practical applications in the clinic - Detailed explanations of historical, exam and biological modeling indexes related to the ANS, corticotropic axis, hepatobiliary and exocrine pancreatic function - Root cause, mechanisms, symptoms and treatments for disorders of immunity, dysbiosis, infectious diseases and spasmophilia, as well as hepatobiliary and pancreatic insufficiency and congestion - Materia medica of 22 key medicinal plants with summary of action and indication of usage according to the theory of Endobigoeny - Special monodiets and dietary suggestions for disorder discussed
Theory of Endobiogeny, Volume 3: Advanced Concepts for Treatment of Complex Clinical Conditions explains complex and multi-factorial disorders and diseases using the theory of endobiogeny. It provides detailed applications of biological modeling, in-depth assessment into common disorders, an endobiogenic analysis, guidance on using biological modeling tools, and suggestions for treatment using standard of care treatments that also take into account diet, lifestyle and medicinal plants. This approach is an evolution in thinking from reductionism to holism, offering advice for symptomatic treatments that can be used in conjunction with a new way of thinking about diseases and disease management. - Covers complex and multi-factorial disorders and diseases using the theory of endobiogeny - Provides detailed applications of biological modeling that can be used within current clinical practice - Extends systems biology from the cell level to the physiology level using pattern recognition
Treating Digestive Disorders from an Endobiogenic Perspective introduces and explains with clarity the concepts, philosophy and practical applications of endobiogenic medicine - a patient-centred diagnostic approach to treatment that originated in France and is now taught across the globe.It explores how a variety of digestive disorders including IBS, Crohn's disease, ulcerative colitis, GERD and dysbiosis, can be resolved with this ground-breaking system. Using in-depth case studies, Paul Michael gives us detailed treatment plans including specific diets, manual therapy and the use of targeted plants and supplements. He alsooffers new insights into the mechanism behind the autoimmune process seen in Crohn's disease and ulcerative colitis from the endobiogenic perspective.
This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?
This full-color reference offers practical, evidence-based guidance on using more than 120 medicinal plants, including how to formulate herbal remedies to treat common disease conditions. A body-systems based review explores herbal medicine in context, offering information on toxicology, drug interactions, quality control, and other key topics. More than 120 herbal monographs provide quick access to information on the historical use of the herb in humans and animals, supporting studies, and dosing information. Includes special dosing, pharmacokinetics, and regulatory considerations when using herbs for horses and farm animals. Expanded pharmacology and toxicology chapters provide thorough information on the chemical basis of herbal medicine. Explores the evolutionary relationship between plants and mammals, which is the basis for understanding the unique physiologic effects of herbs. Includes a body systems review of herbal remedies for common disease conditions in both large and small animals. Discusses special considerations for the scientific research of herbs, including complex and individualized interventions that may require special design and nontraditional outcome goals.
Personalized Medicine is the first English-language introduction to the developing science of endobiogeny. Dr Lapraz developed a diagnostic method that, while being rooted in modern science, allows an insight into the true causes of imbalance and disease in a patient. This innovative medical concept, based on a refined view of the neuro-endocrine system, integrates classical medicine with herbs and supplements, essential oils, and dietary and lifestyle modifications to create a truly holistic treatment approach to illness. The book sets out endobiogenic principles and methods, including the modelling system known as the Biology of Functions, and is full of remarkable case histories that attest to the efficacy of this approach. It is aimed both at the general public and at members of the health professions.
Stress in Health and Disease presents the principal pathways mediating the response to a stressor. It discusses the clinical background of cross-resistance and treatment with stress-hormones. It addresses the diseases of adaptation or stress diseases, diagnostic indicators, and functional changes. Some of the topics covered in the book are the concept of heterostasis; stressors and conditioning agents; morphology of frostbite; characteristics manifestations of stress; catecholamines and their derivatives; various hormones and hormone-like substances; FFA, triglycerides and lipoproteins; morphologic changes; and hypothalamo-hypophyseal system . The gastrointestinal diseases of adaptation are covered. The schizophrenia and related psychoses is discussed. The text describes the manic-depressive disease and senile psychosis. A study of the experimental cardiovascular diseases and neuropsychiatric diseases is presented. A chapter is devoted to the diseases of adaptation in animals. Another section focuses on the shift in adenohypophyseal activity and catatoxic hormones. The book can provide useful information to scientists, doctors, students, and researchers.
Vertebrate Endocrinology represents more than just a treatment of the endocrine system-it integrates hormones with other chemical bioregulatory agents not classically included with the endocrine system. It provides a complete overview of the endocrine system of vertebrates by first emphasizing the mammalian system as the basis of most terminology and understanding of endocrine mechanisms and then applies that to non-mammals. The serious reader will gain both an understanding of the intricate relationships among all of the body systems and their regulation by hormones and other bioregulators, but also a sense of their development through evolutionary time as well as the roles of hormones at different stages of an animal's life cycle. - Includes new full color format includes over 450 full color, completely redrawn image - Features a companion web site hosting all images from the book as PPT slides and .jpeg files - Presents completedly updated and revitalized content with new chapters, such as Endocrine Disrupters and Behavioral Endocrinology - Offers new clinical correlation vignettes throughout