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This biographical study illuminates the important yet misunderstood figure of Barbara McClintock, the Nobel Prize winning geneticist. Comfort replaces the myth with a new story, rich with new understandings of women in science.
In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology affect our understanding of evolution and life’s history. In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important; we now know that roughly eight percent of the human genome arrived sideways by viral infection—a type of HGT. In The Tangled Tree, “the grandest tale in biology….David Quammen presents the science—and the scientists involved—with patience, candor, and flair” (Nature). We learn about the major players, such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health. “David Quammen proves to be an immensely well-informed guide to a complex story” (The Wall Street Journal). In The Tangled Tree, he explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life—including where we humans fit upon it. Thanks to new technologies, we now have the ability to alter even our genetic composition—through sideways insertions, as nature has long been doing. “The Tangled Tree is a source of wonder….Quammen has written a deep and daring intellectual adventure” (The Boston Globe).
Modern web applications are built on a tangle of technologies that have been developed over time and then haphazardly pieced together. Every piece of the web application stack, from HTTP requests to browser-side scripts, comes with important yet subtle security consequences. To keep users safe, it is essential for developers to confidently navigate this landscape. In The Tangled Web, Michal Zalewski, one of the world’s top browser security experts, offers a compelling narrative that explains exactly how browsers work and why they’re fundamentally insecure. Rather than dispense simplistic advice on vulnerabilities, Zalewski examines the entire browser security model, revealing weak points and providing crucial information for shoring up web application security. You’ll learn how to: –Perform common but surprisingly complex tasks such as URL parsing and HTML sanitization –Use modern security features like Strict Transport Security, Content Security Policy, and Cross-Origin Resource Sharing –Leverage many variants of the same-origin policy to safely compartmentalize complex web applications and protect user credentials in case of XSS bugs –Build mashups and embed gadgets without getting stung by the tricky frame navigation policy –Embed or host user-supplied content without running into the trap of content sniffing For quick reference, "Security Engineering Cheat Sheets" at the end of each chapter offer ready solutions to problems you’re most likely to encounter. With coverage extending as far as planned HTML5 features, The Tangled Web will help you create secure web applications that stand the test of time.
Used widely in non-majors biology classes, The Tangled Bank is the first textbook about evolution intended for the general reader. Zimmer, an award-winning science writer, takes readers on a fascinating journey into the latest discoveries about evolution. In the Canadian Arctic, paleontologists unearth fossils documenting the move of our ancestors from sea to land. In the outback of Australia, a zoologist tracks some of the world’s deadliest snakes to decipher the 100-million-year evolution of venom molecules. In Africa, geneticists are gathering DNA to probe the origin of our species. In clear, non-technical language, Zimmer explains the central concepts essential for understanding new advances in evolution, including natural selection, genetic drift, and sexual selection. He demonstrates how vital evolution is to all branches of modern biology—from the fight against deadly antibiotic-resistant bacteria to the analysis of the human genome.
In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology affect our understanding of evolution and life’s history. In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important; we now know that roughly eight percent of the human genome arrived sideways by viral infection—a type of HGT. In The Tangled Tree, “the grandest tale in biology….David Quammen presents the science—and the scientists involved—with patience, candor, and flair” (Nature). We learn about the major players, such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health. “David Quammen proves to be an immensely well-informed guide to a complex story” (The Wall Street Journal). In The Tangled Tree, he explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life—including where we humans fit upon it. Thanks to new technologies, we now have the ability to alter even our genetic composition—through sideways insertions, as nature has long been doing. “The Tangled Tree is a source of wonder….Quammen has written a deep and daring intellectual adventure” (The Boston Globe).
This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1976.
This unique collection of writings by the celebrated author David Madden provides a multitude of reflections on the Civil War and Reconstruction, from nonfiction to fiction. Included are Madden’s examination of key works by historians James McPherson and Fletcher Pratt, the story of the effort to simultaneously burn nine bridges by nine unionist guerrilla bands in the most complicated and coordinated guerrilla tactic of the war, and rediscoveries of both classic and contemporary works of Civil War fiction from William Faulkner, Joseph Stanley Pennell, and more. Alongside these essays are pieces from Madden’s Civil War novel, Sharpshooter, which illustrate the interconnectedness of fiction and nonfiction. This meshing of iconoclastic and controversial pieces includes varied perspectives on every aspect of the war and reconstruction, from culture and civilian life to an imagining of Abraham Lincoln’s critique of how historians have recorded the war and its aftermath. By exploring this web of perception, we can better understand the war and, in turn, shed greater light on the present and the future.
In Germany in the early 1930s the Nazis began rounding up Jews and other undesirables for deportation to concentration camps. The most expensive diamonds were confiscated from these prisoners and shipped to a large collection center south of Berlin. Thirty-six Jewish concentration camp jewelers are assigned the task of appraising these gemstones, that would be used as collateral for Hitlers prosecution of the war. A Yank, a Brit and a band of German patriots devise an audacious scheme to retake the greatest concentration of diamonds in the world. The plans success is threatened, however, when the groups leader suspects a traitor in their midst, turning the mission into a tangled web of intrigue and betrayal.
Proceedings of the Midnight Sun Conference, held in Tromsø, Norway, July 1-8, 1987
The book provides a step by step construction of the framework of relativistic quantum field theory, starting from a minimal set of basic foundational postulates. The emphasis is on a careful and detailed description of the conceptual subtleties of modern field theory, many of which are glossed over in other texts.