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Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.
The skin is the largest organ of the body and serves as a barrier between the inner and external environments. As such, any problems in the skin can have serious effects on systemic health and well-being. Several studies have established that both nutritional and dietary factors play an important role in the maintenance of normal skin integrity, and can execute a causative, preventative and/or treatment role in a number of skin related conditions. Nutritional factors have been studied for their involvement in skin ageing, acne, inflammation and several chronic immune-mediated disorders such as atopic dermatitis, psoriasis, diabetes, obesity, wounds and various types of skin cancer. The skin condition, in turn, can affect nutritional choices and subsequent nutritional and health status. There are a multitude of mechanisms by which nutraceuticals can counteract adverse skin conditions. Consumption of a diet rich in nutrients and vitamins (nutraceuticals and antioxidants), particularly those derived from fruits and vegetables, not only supports health in general, but also skin maintenance and repair in particular. Epidemiological evidence links consumption of these diets with prevention and mitigation of disease progression. For example, nutraceuticals with anti-oxidative or metal chelating properties are being actively evaluated as natural tools to modulate, prevent or inhibit oxidative processes or modulate advanced glycation end products. However, many other properties of dietary compounds with relevance to skin remain to be characterized. For this Special Issue of Nutrients, we have compiled invited manuscripts describing original research, or reviewing scientific literature examining the role of diets and/or specific nutraceuticals in the prevention and treatment of skin disorders. These articles describe the beneficial effects of plant extracts and plant-derived compounds and their ability to ameliorate diverse skin-related conditions including UV damage, aging, atopic dermatitis, psoriasis, and skin cancer. A comprehensive article summarizes the results of current clinical trials on nutraceuticals for various skin afflicitons. Finally, the outcome and research methods used for studies on nutraceuticals and skin function, and their compliance with European regulations is analyzed. Taken together, this compilation of articles provides an up-to-date view of research into the application of nutraceuticals for skin health, for the researcher and anyone interested in the application of natural, plant-derived agents for treatment of skin disease.
Excerpt from The Skin in Health and Disease The writer has endeavored to make this Health Primer serve both as a guide for the preservation of the health of the skin, and as a popular dictionary or encyclopedia in matters pertaining to Dermatology. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science
Excerpt from The Skin, in Health and Disease: A Concise Manual, Treating, in a Popular Form, on the Preservation of the Skin in a Healthy Condition, and on the Treatment of the Diseases to Which It Is Liable; With Cases and Coloured Explanatory Plates In drawing the attention of my readers to this subject, a subject both interesting and important to all, I shall brie y consider the skin under the aspect in which it is commonly presented to our consideration - that is, as consisting of three principal layers, namely - 1, the outer or superficial one, called the cuticle, epidermis, or scarf-skin; 2, the mucous coat, or rete mucosum; and 3, the dermis, cutis vera, or true skin. These are usually considered in connexion with some of the subjacent structures, such as the adipose tissue, or fat, and the delicate net-work of fibres, named the cellular tissue. The Epidermis or scarf-skin, the most superficial layer of the skin, has been by some considered as a perfectly inorganic substance. To this conclusion, which was but natural, these parties have doubtless arrived, from the absence of nerves in its composition, as well as of blood-vessels. To the absence of nerves is due the want of feeling in the outer cuticle, which may be cut to a certain depth without pain, a fact which is in the compass of every one's experience: and from the absence of blood-vessels, or their supposed absence, a want of vitality was inferred. But the inference, is not altogether so clear as the fact; and, further, the grounds upon which it was made have been of late years considerably disturbed, inasmuch as vessels plainly appertaining to the sanguiferous system have been detected in the scarf-skin, and even injected and preserved. Its vitality, however, if vitality it have, is merely vegetative, and though highly sensitive to touch, it is, per se, as before observed, insensible to pain. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works."