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In The Purpose of Futility, Clare Rhoden surveys Australian Great War narratives, demonstrating their particularly Australian features which help to explain the unique and disputed position of the Great War in Australian history.--Provided by publisher
What should happen when doctors and parents disagree about what would be best for a child? When should courts become involved? Should life support be stopped against parents' wishes? The case of Charlie Gard, reached global attention in 2017. It led to widespread debate about the ethics of disagreements between doctors and parents, about the place of the law in such disputes, and about the variation in approach between different parts of the world. In this book, medical ethicists Dominic Wilkinson and Julian Savulescu critically examine the ethical questions at the heart of disputes about medical treatment for children. They use the Gard case as a springboard to a wider discussion about the rights of parents, the harms of treatment, and the vital issue of limited resources. They discuss other prominent UK and international cases of disagreement and conflict. From opposite sides of the debate Wilkinson and Savulescu provocatively outline the strongest arguments in favour of and against treatment. They analyse some of the distinctive and challenging features of treatment disputes in the 21st century and argue that disagreement about controversial ethical questions is both inevitable and desirable. They outline a series of lessons from the Gard case and propose a radical new 'dissensus' framework for future cases of disagreement. - This new book critically examines the core ethical questions at the heart of disputes about medical treatment for children. - The contents review prominent cases of disagreement from the UK and internationally and analyse some of the distinctive and challenging features around treatment disputes in the 21st century. - The book proposes a radical new framework for future cases of disagreement around the care of gravely ill people.
Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods includes updates of established literature from the Wiley Encyclopedia of Clinical Trials as well as original material based on the latest developments in clinical trials. Prepared by a leading expert, the second volume includes numerous contributions from current prominent experts in the field of medical research. In addition, the volume features: • Multiple new articles exploring emerging topics, such as evaluation methods with threshold, empirical likelihood methods, nonparametric ROC analysis, over- and under-dispersed models, and multi-armed bandit problems • Up-to-date research on the Cox proportional hazard model, frailty models, trial reports, intrarater reliability, conditional power, and the kappa index • Key qualitative issues including cost-effectiveness analysis, publication bias, and regulatory issues, which are crucial to the planning and data management of clinical trials
Honorable Mention, 2018 MLA Prize for a First Book Against the defensive backdrop of countless apologetic justifications for the value of literature and the humanities, Futile Pleasures reframes the current conversation by returning to the literary culture of early modern England, a culture whose defensive posture toward literature rivals and shapes our own. During the Renaissance, poets justified the value of their work on the basis of the notion that the purpose of poetry is to please and instruct, that it must be both delightful and useful. At the same time, many of these writers faced the possibility that the pleasures of literature may be in conflict with the demand to be useful and valuable. Analyzing the rhetoric of pleasure and the pleasure of rhetoric in texts by William Shakespeare, Roger Ascham, Thomas Nashe, Edmund Spenser, and John Milton, McEleney explores the ambivalence these writers display toward literature’s potential for useless, frivolous vanity. Tracing that ambivalence forward to the modern era, this book also shows how contemporary critics have recapitulated Renaissance humanist ideals about aesthetic value. Against a longstanding tradition that defensively advocates for the redemptive utility of literature, Futile Pleasures both theorizes and performs the queer pleasures of futility. Without ever losing sight of the costs of those pleasures, McEleney argues that playing with futility may be one way of moving beyond the impasses that modern humanists, like their early modern counterparts, have always faced.
Clinicians recognize that monitoring psychotropic levels provides invaluable information to optimize therapy and track treatment adherence, but they lack formal training specifically focused on the use of plasma antipsychotic levels for these purposes. As new technologies emerge to rapidly provide these results, the opportunity to integrate this information into clinical care will grow. This practical handbook clarifies confusing concepts in the literature on use of antipsychotic levels, providing clear explanations for the logic underlying clinically relevant concepts such as the therapeutic threshold and the point of futility, and how these apply to individual antipsychotics. It offers accessible information on the expected correlation between dosages and trough levels, and also provides a clear explanation of how to use antipsychotic levels for monitoring oral antipsychotic adherence, and methods to help clinicians differentiate between poor adherence and variations in drug metabolism. An essential resource for psychiatrists, psychiatric nurse practitioners, and mental health professionals worldwide.
'Tonight he noticed how the women's eyes Passed from him to the strong men that were whole.' The true horror of the trenches is brought to life in this selection of poetry from the front line. Introducing Little Black Classics: 80 books for Penguin's 80th birthday. Little Black Classics celebrate the huge range and diversity of Penguin Classics, with books from around the world and across many centuries. They take us from a balloon ride over Victorian London to a garden of blossom in Japan, from Tierra del Fuego to 16th-century California and the Russian steppe. Here are stories lyrical and savage; poems epic and intimate; essays satirical and inspirational; and ideas that have shaped the lives of millions. Wilfred Owen (1893-1918). Owen is available in Penguin Classics in Three Poets of the First World War: Ivor Gurney, Isaac Rosenberg, Wilfred Owen.
The horrors of the First World War released a great outburst of emotional poetry from the soldiers who fought in it as well as many other giants of world literature. Wilfred Owen, Rupert Brooke and W B Yeats are just some of the poets whose work is featured in this anthology. The raw emotion unleashed in these poems still has the power to move readers today. As well as poems detailing the miseries of war there are poems on themes of bravery, friendship and loyalty, and this collection shows how even in the depths of despair the human spirit can still triumph.