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Standing as the only text focused on the pharmaceutical treatment of asthma, this reference details the pharmacology, mechanisms of action, efficacy, and safety of every drug currently used in the management and care of asthma patients. Internationally renowned authorities cover published practice guidelines, treatment plans, pharmacologic agents, and clinical studies to provide the most authoritative and up-to-date information on the use of medications to control and prevent this common condition. Reviewing the role of pharmacotherapy in the overall management of asthma, this guide: * reviews the pharmacology and clinical use of inhaled corticosteroids, beta adrenergic agonists, leukotriene modifiers, combination products, and many other asthma drugs * provides a practical framework for the optimal pharmacotherapy of asthma, focusing on outpatient therapy * examines international guidelines for the drug treatment of asthma.
This volume forms part of a prestigious series and covers the latest advances in our understanding of the pathophysiology and treatment of asthma. Our understanding of asthma has changed dramatically in recent years, and much of this new information is brought together in this volume written by inter nationally recognised authorities. The aim of the book is to review in depth the changing concepts of inflammatory processes in asthma and to discuss the implications for research of this common chronic disease. Many of the advances in and future therapy our understanding of asthma have originated from a pharmacological approach, and this volume highlights the promising new options for pharma cological intervention. It is hoped this book will be invaluable for research scientists and clinic ians involved in asthma research and will be a major reference resource for chest physicians and those involved in the development of novel pharmaceu tical entities. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this growing area. c.P. PAGE P.l. BARNES Contents CHAPTER 1 The Pathology of Asthma: An Overview L.A. LAmNEN and A. LAmNEN. With 10 Figures ...................... 1 A. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 1 . . . . . . . . . . . . . . . B. Methods to Investigate the Pathology of Human Asthma ............ 1 C. Bronchial Epithelium and Inflammatory Cells in Asthmatic Patients Between Attacks ........................... 2 I. Mast Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 4 . . . . . . . . . . . . . . II. Eosinophils ............................................... 7 III. Neutrophils.............................................. 10 D. Bronchial Epithelial Inflammation During an Asthma Attack. . . . . .. . 10 E. Epithelial Regeneration .... . . . . . . . . . . . . . . . . . . . . . . .. . . 12 . . . . . . . . .
This comprehensive, first-of-its kind title is an indispensable resource for pharmacists looking to learn or improve crucial patient assessment skills relevant to all pharmacy practice settings. Pharmacists’ role as health care practitioners is evolving as they are taking a more active part in primary patient care -- helping patients manage their medications and diseases, providing patient education, and, in some jurisdictions, prescribing and adapting medications. To perform their day-to-day duties, pharmacists are best-served using a framework called the patient care process. This framework involves three steps: patient assessment; care plan development and implementation; and monitoring and follow up. Organized in four parts, this practical book begins with introductory chapters regarding the basics of patient assessment and the patient care process. Part II includes a detailed assessment of common symptoms encountered by pharmacists. Part III discusses assessment of patients with various chronic illnesses. Part IV addresses select specialized topics and assessment considerations. An invaluable contribution to the literature, Patient Assessment in Clinical Pharmacy: A Comprehensive Guide will be of great benefit to pharmacists, regardless of their practice setting, and to pharmacy students as well.
The aim of the book is to provide an in-depth review of our current understanding of the pathogenesis of both asthma and COPD. This volume also discusses the promising new options for pharmacological intervention of these diseases. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this important area of lung biology.
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
A concise introductory guide to asthma, the medicines used in its treatment, and the role of the pharmacist and other healthcare professionals in counselling patients on their illness, lifestyle and medicines. This guide discusses the drugs used to treat the disease, and describes how the pharmacist can get involved in counselling patients.
The long-acting beta-2-agonists have become indispensible in modern asthma therapy. But do they have a fixed position in international guidelines? Here are the proceedings of the 6th Vienna Asthma Forum, when molecular biologists, drug designers, and clinicians discussed the role of three compounds (bambuterol, formoterol, and salmeterol) on a high scientific level. The authors give a fascinating new insight into the physiology of the Beta2- and glucocorticoid receptor, into the considerations before and during drug development, stimulating a vivid discussion among clinical researchers who share a special interest in the most efficacious use of a new therapeutic principle. The original papers and the individual discussions are highly informative and delightful to read.
Learn the art and science of patient assessment to succeed in real-world pharmacy practice The goal of Patient Assessment in Pharmacy is to impart the assessment and practice skills necessary to provide optimal patient care when working in an ambulatory care environment. This unique text explains how to integrate pathophysiology, medical history, physical findings, and laboratory test results to accurately assess and monitor patient problems. Patient Assessment in Pharmacy will help you make a more accurate diagnosis and enable you to better advise patients about appropriate use of products intended for self-care. In order to be as clinically relevant as possible,Patient Assessment in Pharmacy focuses on the symptom complexes and diseases that pharmacists most frequently encounter in an ambulatory care setting.