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The Pharmacological Potential of Cyanobacteria explores the bioactive compounds isolated from cyanobacteria and their relationship to human health and biotechnological applications. The book presents an overview of the chemistry and ecology of cyanobacteria, focusing on culture needs and techniques of biomass production. It is organized according to the different biological activities and biotechnological applications of compounds discovered in recent years. Besides biological activity, the mechanism of action of compounds is explained, along with molecular structure. Finally, compounds already used in therapeutics and biotechnology, as well as those in phases of approval or clinical trials are explored. Each chapter is written by a different research group with expertise in the field and publications in peer reviewed journals. Researchers and students in pharmaceutical academic research, pharmaceutical industrial sector personnel, health professionals, and nutritionists will find this book to be very useful. - Covers all the bioactive compounds of cyanobacteria discovered thus far - Includes chapters by experts in the field, covering the chemistry and mechanisms of action of cyanobacteria-bioactive compounds - Provides a general overview of organisms, from biomass production to compound isolation and evaluation of bioactivities in different cell and cell-free systems
This revised and extended edition provides in-depth insights into the benefits and untapped potential of lichen-derived bioactive compounds. The whole spectrum of these compounds’ biological and medical functions, from antibiotic to antiviral and anti-carcinogenic properties, is presented. In addition, a new chapter discusses the anti-neurodegenerative and anti-diabetic activities of lichenic secondary metabolites. Given its scope, the book offers a valuable asset for students and researchers in this field.
Provides a comprehensive overview of key methods for treating water tainted by cyanobacteria and cyanotoxins Toxigenic cyanobacteria are one of the main health risks associated with water resources. Consequently, the analysis, control, and removal of cyanobacteria and cyanotoxins from water supplies is a high priority research area. This book presents a comprehensive review of the state-of-the-art research on water treatment methods for the removal of cyanobacteria, taste and odor compounds, and cyanotoxins. Starting with an introduction to the subject, Water Treatment for Purification from Cyanobacteria and Cyanotoxins offers chapters on cyanotoxins and human health, conventional physical-chemical treatment for the removal of cyanobacteria/cyanotoxins, removal of cyanobacteria and cyanotoxins by membrane processes, biological treatment for the destruction of cyanotoxins, and conventional disinfection and/or oxidation processes. Other chapters look at advanced oxidation processes, removal/destruction of taste and odour compounds, transformation products of cyanobacterial metabolites during treatment and integrated drinking water processes. Provides a comprehensive overview of key methods for treating water tainted by cyanobacteria and cyanotoxins Bridges the gap between basic knowledge of cyanobacteria/cyanotoxins and practical management guidelines Includes integrated processes case studies and real-life examples Developed within the frame of the European Cooperation in Science and Technology (COST)–funded CYANOCOST A must-have resource for every water treatment plant, Water Treatment for Purification from Cyanobacteria and Cyanotoxins is a valuable resource for all researchers in water chemistry and engineering, environmental chemistry as well as water companies and authorities, water resource engineers and managers, environmental and public health protection organizations.
Advances in Cyanobacterial Biology presents the novel, practical, and theoretical aspects of cyanobacteria, providing a better understanding of basic and advanced biotechnological application in the field of sustainable agriculture. Chapters have been designed to deal with the different aspects of cyanobacteria including their role in the evolution of life, cyanobacterial diversity and classification, isolation, and characterization of cyanobacteria through biochemical and molecular approaches, phylogeny and biogeography of cyanobacteria, symbiosis, Cyanobacterial photosynthesis, morphological and physiological adaptation to abiotic stresses, stress-tolerant cyanobacterium, biological nitrogen fixation. Other topics include circadian rhythms, genetics and molecular biology of abiotic stress responses, application of cyanobacteria and cyanobacterial mats in wastewater treatments, use as a source of novel stress-responsive genes for development of stress tolerance and as a source of biofuels, industrial application, as biofertilizer, cyanobacterial blooms, use in Nano-technology and nanomedicines as well as potential applications. This book will be important for academics and researchers working in cyanobacteria, cyanobacterial environmental biology, cyanobacterial agriculture and cyanobacterial molecular biologists.
Unites a biological and a biotechnological perspective on cyanobacteria, and includes the industrial aspects and applications of cyanobacteria Cyanobacteria Biotechnology offers a guide to the interesting and useful features of cyanobacteria metabolism that keeps true to a biotechnology vision. In one volume the book brings together both biology and biotechnology to illuminate the core acpects and principles of cyanobacteria metabolism. Designed to offer a practical approach to the metabolic engineering of cyanobacteria, the book contains relevant examples of how this metabolic "module" is currently being engineered and how it could be engineered in the future. The author includes information on the requirements and real-world experiences of the industrial applications of cyanobacteria. This important book: Brings together biology and biotechnology in order to gain insight into the industrial relevant topic of cyanobacteria Introduces the key aspects of the metabolism of cyanobacteria Presents a grounded, practical approach to the metabolic engineering of cyanobacteria Offers an analysis of the requirements and experiences for industrial cyanobacteria Provides a framework for readers to design their own processes Written for biotechnologists, microbiologists, biologists, biochemists, Cyanobacteria Biotechnology provides a systematic and clear volume that brings together the biological and biotechnological perspective on cyanobacteria.
The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products cover the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.
Microalgae in Health and Disease Prevention is a comprehensive reference that addresses the historical and potential use of microalgae, its extracts, secondary metabolites, and molecular constituents for enhancing human health and preventing diseases. Each chapter features an overview, and the book includes coverage of microalgae biology, harmful algae, the use of microalgae in alcohol and food, and as sources of macronutrients, micronutrients, vitamins, and minerals. The historical use of microalgae, in addition to its potential use as a nutraceutical and cosmeceutical, is also addressed. The book provides coverage of relevant, up-to-date research as assembled by a group of contributors who are dedicated to the advancement of microalgae use in health, diet and nutrition. Discusses research findings on the relationship between microalgal diet, nutrition and human health Presents the medicinal, anti-allergic and psychoactive properties of microalgae Identifies toxic and harmful microalgae Addresses microalgal lipids, proteins and carbohydrates
The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified—natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products as lead compounds in drug discovery, Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery is actually a completely new volume containing surveys of selected recent advances in an interdisciplinary area covering chemistry of natural products, medicinal chemistry, biochemistry, and other related topics. Written by some of the most reputed scientists in the field, this second edition includes new chapters from authors who contributed to the first edition as well as many chapters compiled by new authors. Introducing the reader to strategies and methods in the search for bioactive natural products, this book covers topics including: Natural sources of bioactive compounds such as aquatic cyanobacteria, filamentous fungi, and tropical plants, The tremendous potentiality of metabolic engineering of natural products biosynthesis The contribution of emerging or developing technologies to the study of bioactive natural compounds, namely computational methods and circular dichroism The potential of natural or natural-derived compounds for specific therapeutic applications: treatment of viral diseases, regulation of hypoxia-inducible factor, antimalarials, modulation of angiogenesis, and antitumor and wound-healing activity Selected examples of natural product families and related synthetic analogues, namely polyphenols and campthotecins Compiled for researchers and Ph.D. students working in interdisciplinary fields, this book will also be appreciated by readers without a background in chemistry interested in bioactive natural products, their biological and pharmacological properties, and their possible use as chemopreventive or chemotherapeutic agents. Conversely, the biological and pharmacological data and methods are accessible by chemists.