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Now in its fourth edition, Pathology of Laboratory Rodents and Rabbits has become a standard text for veterinary pathologists, laboratory animal veterinarians, students, and others interested in these species. • The standard reference on the pathogenesis and cardinal diagnostic features of diseases of mice, rats, hamsters, gerbils, guinea pigs, and rabbits • Expanded coverage of rabbit disease, normal anatomic features, and biology • Over 450 color photographs illustrating gross and microscopic pathology • Companion website offering images from the text in PowerPoint
Laboratory Animal Medicine has made enor We deeply appreciate the efforts of each of the mous strides in the 47 years since R. Jaffe published authors and co-authors of the 23 chapters in this his "Anatomy and Pathology of Spontaneous Dis two volume work. In some instances the reader will eases of Small Laboratory Animals" in 1931. So note what appears to be repetition in certain chap ters. This repetition was allowed to stand in some much new information had accumulated that in a cases because different approaches seemed useful, new edition in 1958, Jaffe, aided by Cohrs and Meessen, needed the assistance of 46 colleagues to although efforts were made to delete most of the do the subject justice. Like its predecessor, this two redundancy which inevitably arises in a venture of volume comprehensive treatise on "Pathologie der this kind. We will be grateful if our colleagues point out errors and send us specific and general Laboratoriumstiere" was written in German and criticism of this work to allow corrections in the thus not readily available to the widening circle of event of reprinting or a next edition. veterinarians and pathologists who now are inter One objective has been to assemble current in ested in laboratory animals. Aside from the need to have a comprehensive formation in the pathologic aspects of diseases of review of laboratory animal pathology in English, laboratory animals.
Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas. - over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits - a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals - a chapter on common artifacts that may be observed in histological glass slides - extensive references to each lesion described - aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies
Pathology of Wildlife and Zoo Animals is a comprehensive resource that covers the pathology of wildlife and zoo species, including a wide scope of animals, disease types and geographic regions. It is the definitive book for students, biologists, scientists, physicians, veterinary clinicians and pathologists working with non-domestic species in a variety of settings. General chapters include information on performing necropsies, proper techniques to meet the specialized needs of forensic cases, laboratory diagnostics, and an introduction into basic principles of comparative clinical pathology. The taxon-based chapters provide information about disease in related groups of animals and include descriptions of gross and histologic lesions, pathogenesis and diagnostics. For each group of animals, notable, unique gross and microscopic anatomical features are provided to further assist the reader in deciding whether differences from the domestic animal paradigm are "normal." Additional online content, which includes text, images, and whole scanned glass slides of selected conditions, expands the published material resulting in a comprehensive approach to the topic. - 2019 PROSE Awards - Winner: Category: Textbook/Biological and Life Sciences: Association of American Publishers - Presents a single resource for performing necropsies on a variety of taxa, including terrestrial and aquatic vertebrates and invertebrates - Describes notable, unique gross and microscopic anatomical variations among species/taxa to assist in understanding normal features, in particular those that can be mistaken as being abnormal - Provides consistent organization of chapters with descriptions of unique anatomic features, common non-infectious and infectious diseases following brief overviews of the taxonomic group - Contains full-color, high quality illustrations of diseases - Links to a large online library of scanned slides related to topics in the book that illustrate important histologic findings
This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.
Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Clinical Laboratory Animal Medicine: An Introduction, Fourth Edition offers a user-friendly guide to the unique anatomy and physiology, care, common diseases, and treatment of small mammals and nonhuman primates. Carefully designed for ease of use, the book includes tip boxes, images, and review questions to aid in comprehension and learning. The Fourth Edition adds new information on transgenic mice, drug dosages, techniques, and environmental enrichment, making the book a comprehensive working manual for the care and maintenance of common laboratory animals. The book includes information on topics ranging from genetics and behavior to husbandry and techniques in mice, rats, gerbils, hamsters, guinea pigs, chinchillas, rabbits, ferrets, and nonhuman primates. A companion website provides editable review questions and answers, instructional PowerPoints, and additional images not found in the book. Clinical Laboratory Animal Medicine is an invaluable resource for practicing veterinarians, veterinary students, veterinary technicians, and research scientists.
Pathology of Small Mammal Pets presents a ready reference for veterinarians, veterinary pathologists, and technicians who work with small mammal companion animals. Provides up-to-date, practical information on common disease conditions in small mammal companion animals Offers chapters logically organized by species, with comprehensive information on diagnosing diseases in each species Takes a practical, system-based approach to individual disease conditions Covers clinical signs, laboratory diagnostics, gross pathology, histopathology, and differential diagnoses in detail Includes relevant information for conventional breeding operations and breeding facilities, with strategies for disease management in herds and colonies Features information on normal anatomy in included species to assist in recognizing pathology
This book, edited in partnership with the American College of Laboratory Medicine (ACLAM), is the most comprehensive reference available on in vivo animal studies as a critical part of biomedical research. It covers relevant laboratory animal species, specific organ systems and important classes of analytes.
A complete update on the safety testing of foods, drugs, and chemicals in laboratory animals, featuring: - a thorough review of each subject area with extensive revision in line with new information and concepts - electron micrographs in exquisite detail to illustrate results of recent research - the effects of many carcinogens described succinctly and illustrated in detail - neoplasms described in detail and compared with natural and induced tumours in other species - standardised nomenclature. Of interest to those interested in the many applications to human patients, Urinary System: - facilitates uniform interpretation of bioassay results world-wide - provides a basis for understanding mechanisms involved in the functions and malfunctions of the most minute, but important structures of the kidneys - explains the functional significance of details by identifying the composition of structures at the molecular level. Forming a solid basis for understanding the causes and effects of disease of the urinary system, this is essential reading for pathologists, toxicologists, regulatory agencies, and all those involved in carcinogenicity and toxicity studies.