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This book summarises the current knowledge on the role played by biologically relevant transition metals (Fe, Mn, Zn, Ni, Co, Cu and Mg) in the basic biology and virulence of bacterial pathogens from the genus Brucella. The authors explore the biological functions of these metals, how these bacteria compete with their mammalian hosts for these metals and how they avoid metal toxicity. Researchers and professionals studying zoonotic pathogens from the genus Brucella find this book valuable.
Fourteen brucellosis experts from seven countries discuss the history, epidemiology, microbiology, immunology, diagnosis, treatment, and control of brucellosis in animals and man. Edited by members of the World Health Organization's Expert Committee on Brucellosis, this text is the first comprehensive treatment of the disease since The Nature of Brucellosis by Wesley W. Spink in 1956. Topics reviewed with current references include infection caused by newer species of Brucella, such as B. canis, newer diagnostic techniques, such as radioimmunoassay and ELISA, and newer treatments, such as rifampin and the quinolones. The pathogenesis and pathophysiology of brucellosis is reviewed in depth, correlating the disease in animals with the illness in humans. This volume is extremely useful for clinicians, researchers, and students in medicine, veterinary science, microbiology, immunology, epidemiology, public health, and international health.
A full description of the clinical aspect and pathology of the disease, with a discussion of current treatment. This updated edition includes five new chapters: endocrinal brucellosis, difficulties in diagnosis and management, HIV and brucellosis, bioterrorism and brucellae, and spondylitis with neurobrucellosis. The book presents a complete, up-to-date picture of the disorder and will appeal to clinicians, students, researchers and also to veterinarians.
This very well-received book, now in its second edition, equips the radiologist with the information needed in order to diagnose internal medicine disorders and their complications from the radiological perspective. It offers an easy-to-consult tool that documents the most common and most important radiological signs of a wide range of diseases, across diverse specialties, with the aid of an excellent gallery of images and illustrations. Compared with the first edition, numerous additions and updates have been made, with coverage of additional disorders and inclusion of many new images. Entirely new chapters focus on occupational medicine and toxicology imaging, chiropractic medicine, and energy and quantum medicine. Internal Medicine – An Illustrated Radiological Guide puts the radiologist in the internal medicine physician’s shoes. It teaches radiologists how to think in terms of disease progression and complications, explains where to look for and to image these complications, and identifies the best modalities for reaching a diagnosis. It will also benefit internal medicine physicians by clarifying the help that radiology can offer them and assisting in the choice of investigation for diagnostic confirmation.
Brucellosis is a major zoonotic disease that may cause a serious illness in humans and animals. Global prevalence of human brucellosis remains significant. More than half a million new brucellosis cases from 100 countries are reported annually to the World Health Organization (WHO). The majority of these cases are reported in developing countries.In humans, brucellosis (undulant fever, Malta fever) is characterized by an acute bacteremic phase followed by a chronic stage that may extend over many years and may involve many tissues. It is a systemic disease, and many organ systems (nervous system, heart, skeletal system, bone marrow, etc.) may become involved following hematogenous dissemination. Although eradicated in some countries, it remains one of the most economically important zoonosis worldwide as it is responsible for huge economic losses as well as significant human morbidity in endemic areas. Because of the nonspecific clinical manifestations of human brucellosis and the need for prolonged combination therapy with antibiotics that are not routinely prescribed for other infectious diseases, laboratory confirmation of the diagnosis is of paramount importance for adequate patient management. In addition, evidence of brucellosis has serious public health implications because it discloses exposure to a contaminated source (infected animals or their products, unsafe laboratory practices, or a potential biological warfare attack). This book addresses human brucellosis with stress on symptoms including those related to the less recognized disease localizations, risk of exposure, treatment, and prevention. Light is shed on animal brucellosis as it pertains to human exposure. The book also emphasizes on laboratory procedures in culturing and serologic techniques. Epidemiologic surveillance is among this books subjects as well as veterinary control measures.
Atlas of Lymph Node Pathology reviews the histopathology of nodal diseases, illustrating the use of ancillary studies and includes concise discussions of pathogenesis, clinical settings and clinical significance of the pathologic diagnosis. The atlas features an overview of the benign reactive processes secondary to infectious, environmental or unknown insults, as well as relevant illustrations of virtually all primary and secondary neoplasms involving lymph nodes. The atlas also includes macroscopic images of some disorders, tables that help readers understand and comprehend diseases that look alike, and diagnostic algorithms for certain groups of diseases. Authored by highly experienced pathologists, Atlas of Lymph Node Pathology is a valuable resource that illustrates the vast majority of diseases practicing pathologists, clinicians and oncologists are likely to encounter in daily practice.
Brucellosis, also known as undulant fever, Mediterranean fever, or Malta fever, is an important human disease in many parts of the world. It is a zoonosis and the infection is almost invariably transmitted to people by direct or indirect contact with infected animals or their products. These Guidelines are designed as a concise, yet comprehensive, statement on brucellosis for public health, veterinary and laboratory personnel without access to specialized services. They are also to be a source of accessible and updated information for such others as nurses, midwives and medical assistants who may have to be involved with brucellosis in humans. Emphasis is placed on fundamental measures of environmental and occupational hygiene in the community and in the household as well as on the sequence of actions required to detect and treat patients.