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In the aftermath of Prohibition, America's top scientists joined forces with AA members and put their clout behind a campaign to convince the nation that alcoholism is a disease. They had no proof, but they hoped to find it once research money came pouring in. The campaign spanned decades, and from it grew a multimillion-dollar treatment industry and a new government agency devoted to alcoholism. But scientists' research showed that problem drinking is not a singular disease but a complex phenomenon requiring an array of strategies. There's less scientific evidence for the effectiveness of AA than there is for most other treatments, including self-enforced moderation, therapy and counseling, and targeted medications; AA's own surveys show that it doesn't work for the overwhelming majority of problem drinkers. Five years in the making, Joe Miller's brilliant, in-depth investigative reporting into the history, politics, and science of alcoholism shows exactly how AA became our nation's de facto treatment policy, even as evidence accumulated for more effective remedies—and how, as a result, those who suffer the most often go untreated. US of AA is a character-driven, beautifully written exposÉ, full of secrecy, irony, liquor industry money, the shrillest of scare tactics, and, at its center, a grand deception. In the tradition of Crazy by Pete Earley and David Goldhill's Catastrophic Care, US of AA shines a much-needed spotlight on the addiction treatment industry. It will forever change the way we think about the entire enterprise.
An African-American boy idolises world champion prize-fighter Joe Louis as a boxer and a role model.
Winners of the Paul Ehrlich Prize The dramatic story of the married scientists who founded BioNTech and developed the first vaccine against COVID-19. Nobody thought it was possible. In mid-January 2020, Ugur Sahin told Özlem Türeci, his wife and decades-long research partner, that a vaccine against what would soon be known as COVID-19 could be developed and safely injected into the arms of millions before the end of the year. His confidence was built upon almost thirty years of research. While working to revolutionize the way that cancerous tumors are treated, the couple had explored a volatile and overlooked molecule called messenger RNA; they believed it could be harnessed to redirect the immune system's forces against any number of diseases. As the founders of BioNTech, they faced widespread skepticism from the scientific community at first; but by the time Sars-Cov-2 was discovered in Wuhan, China, BioNTech was prepared to deploy cutting edge technology and create the world’s first clinically approved inoculation for the coronavirus. The Vaccine draws back the curtain on one of the most important medical breakthroughs of our age; it will reveal how Doctors Sahin and Türeci were able to develop twenty vaccine candidates within weeks, convince Big Pharma to support their ambitious project, navigate political interference from the Trump administration and the European Union, and provide more than three billion doses of the Pfizer/BioNTech vaccine to countries around the world in record time. Written by Joe Miller—the Financial Times’ Frankfurt correspondent who covered BioNTech’s COVID-19 project in real time—with contributions from Sahin and Türeci, as well as interviews with more than sixty scientists, politicians, public health officials, and BioNTech staff, the book covers key events throughout the extraordinary year, as well as exploring the scientific, economic, and personal background of each medical innovation. Crafted to be both completely accessible to the average reader and filled with details that will fascinate seasoned microbiologists, The Vaccine explains the science behind the breakthrough, at a time when public confidence in vaccine safety and efficacy is crucial to bringing an end to this pandemic.
Reinvent yourself as a woman of influence—and become the leader you were meant to be Have you ever felt like your organization’s best-kept secret? Are you the go-to person for work that downplays your potential? Do you want to hone your leadership skills while still staying true to who you are? If you answered yes to any of these questions, or if your reputation as a standout contributor is not translating into career advancement, Woman of Influence is for you. With more than two decades of experience working with hundreds of thousands of women and clients including eBay, GM, Microsoft, and more, Be Leaderly CEO Jo Miller has the strategies, stories, and research to help women shift their focus from doing to leading. In Woman of Influence, she provides a practical, hands-on roadmap that walks you through 9 specific steps to build your brand, establish your legacy, and thrive. Each step is reinforced with self-assessments, inspiring exercises, and checklists that have been road-tested by tens of thousands of professional women.
"To an astonishing extent, the 1920s resemble our own era, at the turn of the twenty-first century; in many ways that decade was a precursor of modern excesses....Much of what we consider contemporary actually began in the Twenties." -- from the Introduction The images of the 1920s have been indelibly imprinted on the American imagination: jazz, bootleggers, flappers, talkies, the Model T Ford, Babe Ruth, Charles Lindbergh's history-making flight over the Atlantic. But it was also the era of the hard-won vote for women, racial injustice, censorship, widespread social conflict, and the birth of organized crime. Bookended by the easy living of the Jazz Age, when the booze and money flowed seemingly without end, and the crash of '29 that led to breadlines and a level of human suffering not seen since World War I, New World Coming is a lively, entertaining, and all-encompassing chronological account of an age that defined America. Chronicling what he views as the most consequential decade of the past century, Nathan Miller -- an award-winning journalist and five-time Pulitzer nominee -- paints a vivid portrait of the 1920s, focusing on the men and women who shaped that extraordinary time, including, ironically, three of America's most conservative presidents: Harding, Coolidge, and Hoover. In the Twenties, the American people soared higher and fell lower than they ever had before. As unprecedented economic prosperity and sweeping social change dazzled the public, the sensibilities and restrictions of the nineteenth century vanished, and many of the institutions, ideas, and preoccupations of our own age emerged. With scandal, sex, and crime the lifeblood of the tabloids, the contemporary culture of celebrity and sensationalism took root and journalism became popular entertainment. By discarding Victorian idealism and embracing twentieth-century skepticism, America became, for the first time, thoroughly modernized. There is hardly a dimension of our present world, from government to popular culture, that doesn't trace its roots to the 1920s, and few decades are more intriguing or significant today. The first comprehensive view of the era since Only Yesterday, Frederick Lewis Allen's 1931 classic, New World Coming reveals this remarkable age from the vantage point of nearly a century later. It's all here -- the images and the icons, the celebrities and the legends -- in a book that will resonate with history readers, 1920s aficionados, and Americans everywhere.