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Excerpt from The Journal of Tuberculosis, 1899 The evolution of specific medication for infectious diseases has made enough progress, at this time, to justify the serious and thoughtful attention of medical men, and supplies a most interesting and gratifying chapter in the history of medicine of the closing century. In Tuberculosis this is only less apparent to those who lose sight of the limitations that all remedies must have in their power of removing pathological processes which frequently attain a degree from which recovery or even im provement is absolutely impossible. The pathological changes of tubercle are no exception to this general truth, as we recognize it for instance, in syphilis, where stages are often reached in which specific medication is absolutely useless. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Excerpt from The New York Medical Journal: July 1, 1899 The last is the important item. In twenty - two cases we found tuberculous meningitis. In some few' cases this was limited to the presence of miliary tubercles; in most, the miliary tubercles were accompanied by more or less plastic exudation, especially at the base of the brain. We may safely say that in all these cases the meningitis was the direct cause of death. In addition to the complications thus far mentioned, we need only say that in two cases, where the chief lesion was confined to the bones and was accompanied by prolonged suppuration, we found extensive waxy de' generation of the viscera. In all but two cases meningitis was either a part of a general miliary tuberculosis or was accompanied by advanced changes in lungs - hopeless. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Excerpt from North Carolina Medical Journal, Vol. 44: A Semi-Monthly Journal of Medicine and Surgery; July 5, 1899 Other anti-toxins for the cure of pneumonia, cholera, the bubonic plague, typhoid fever, yellow fellow, tuberculosis and snake venom, are passing through the experimental stage with varying degrees of success. But their place is still in the laboratory, and in the hands of the most careful observer, nor should they be hysterically thrust upon the general profession until the proof of their potency and value as therapeutic agents has been established beyond all reasonable doubt. They represent, however, the first steps taken in a field of almost boundless extent, which holds truths that medical science will yet convert into blessings of priceless value to mankind. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Tuberculosis (TB) remains one of the major infectious diseases of mankind although drugs for its treatment have been available for nearly 60 years. The standard short-course 6-month regimen used since about 1980 has helped to save millions of lives, but co-infection with HIV has had a devastating effect on the epidemic, and multidrug-resistant TB is a growing problem, particularly in communities with a high incidence of HIV. Following the declaration by the WHO in the early 1990s that TB was a 'global health emergency', interest in TB research and the development of new drugs has increased significantly. This volume reviews anti-TB chemotherapy with the emphasis on the actions and pharmacology of existing drugs and the development and evaluation of new agents. A close look is taken at new research regarding our existing drugs by some of the best-known specialists in the field, and historical aspects of these agents are reviewed from a modern perspective. The prospects for the introduction of new drugs and different approaches of how to assess them in adults and in children are discussed in detail. Several papers address the problems associated with drug resistance, its spread and diagnosis. Compiled by two editors from Cape Town, which has a particularly high incidence of TB and is a centre of tuberculosis research, this publication is an indispensable reference for anyone involved in the management of TB either as a researcher, clinician or administrator, and those working in drug development.