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How tiny variations in our personal DNA can determine how we look, how we behave, how we get sick, and how we get well. News stories report almost daily on the remarkable progress scientists are making in unraveling the genetic basis of disease and behavior. Meanwhile, new technologies are rapidly reducing the cost of reading someone's personal DNA (all six billion letters of it). Within the next ten years, hospitals may present parents with their newborn's complete DNA code along with her footprints and APGAR score. In Genetic Twists of Fate, distinguished geneticists Stanley Fields and Mark Johnston help us make sense of the genetic revolution that is upon us. Fields and Johnston tell real life stories that hinge on the inheritance of one tiny change rather than another in an individual's DNA: a mother wrongly accused of poisoning her young son when the true killer was a genetic disorder; the screen siren who could no longer remember her lines because of Alzheimer's disease; and the president who was treated with rat poison to prevent another heart attack. In an engaging and accessible style, Fields and Johnston explain what our personal DNA code is, how a few differences in its long list of DNA letters makes each of us unique, and how that code influences our appearance, our behavior, and our risk for such common diseases as diabetes or cancer.
Research today demands the application of sophisticated and powerful research tools. Fulfilling this need, The Oxford Handbook of Quantitative Methods is the complete tool box to deliver the most valid and generalizable answers to todays complex research questions. It is a one-stop source for learning and reviewing current best-practices in quantitative methods as practiced in the social, behavioral, and educational sciences. Comprising two volumes, this handbook covers a wealth of topics related to quantitative research methods. It begins with essential philosophical and ethical issues related to science and quantitative research. It then addresses core measurement topics before delving into the design of studies. Principal issues related to modern estimation and mathematical modeling are also detailed. Topics in the handbook then segway into the realm of statistical inference and modeling with chapters dedicated to classical approaches as well as modern latent variable approaches. Numerous chapters associated with longitudinal data and more specialized techniques round out this broad selection of topics. Comprehensive, authoritative, and user-friendly, this two-volume set will be an indispensable resource for serious researchers across the social, behavioral, and educational sciences.
The Minnesota Study of Twins Reared Apart startled scientists by demonstrating that twins reared apart are as alike, across a number of personality traits and other measures, as those raised together, suggesting that genetic influence is pervasive. Segal offers an overview of the study’s scientific contributions and effect on public consciousness.
Twin Mythconceptions: False Beliefs, Fables, and Facts about Twins sheds new light on over 70 commonly held ideas and beliefs about the origins and development of identical and fraternal twins. Using the latest scientific findings from psychology, psychiatry, biology, and education, the book separates fact from fiction. Each idea about twins is described, followed by both a short answer about the truth, and then a longer, more detailed explanation. Coverage includes embryology of twins, twin types, intellectual growth, personality traits, sexual orientation of twins, marital relationships, epigenetic analyses, and more. Five appendices cover selected topics in greater depth, such as the frequency of different twin types and the varieties of polar body twin pairs. This book will inform and entertain behavioral and life science researchers, health professionals, twins, parents of twins, and anyone interested in the fascinating topic of twins. - Identifies common misunderstandings about twins - Provides scientific answers to questions about twins - Encompasses the biology, psychology, genetics, and personality of twins - Includes discussion of identical, fraternal same-sex, and fraternal opposite-sex twins - Allows for quick answers to common questions and more detailed explanations
Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels, placentation and amniotic fluid are also examined, while full color images illustrate discordant anomalies and twin differences throughout. - Examines the major causes of discordance in monozygotic twins and their relevance for future studies and clinical management - Discusses NIPT in MZ twins, twin imaging during fetal development, blood tests and forensic analysis - Features contributions from international experts in twin genetics and developmental biology
The Encyclopedia of Personality and Individual Differences (EPID) beschäftigt sich in vier Bänden mit Gemeinsamkeiten und Unterschieden bei Individuen. Jeder Band konzentriert sich auf einen wichtigen Themenbereich bei der Untersuchung der Persönlichkeitspsychologie und den Unterschieden von Individuen. Der erste Band mit dem Titel Models and Theories betrachtet die wichtigsten klassischen und modernen Standpunkte, Perspektiven, Modelle und theoretischen Ansätze im Studium der Persönlichkeit und Unterschiede von Individuen. Der zweite Band, Measurement and Assessment, untersucht die wesentlichen klassischen und modernen Beurteilungsmethoden und -techniken. Der dritte Band mit dem Titel Personality Processes and Individual Differences erläutert die traditionellen und aktuellen Dimensionen, Konstrukte und Merkmale der Studienrichtung. Im vierten Band werden drei Hauptkategorien behandelt: klinische Zuarbeit, angewandte Forschung und interkulturelle Betrachtungen. Darüber hinaus werden Themen wie Kultur und Identität, multikulturelle Identitäten, interkulturelle Untersuchungen von Merkmalsstrukturen und Personalitätsprozesses u. v. m. behandelt. - Jeder Band enthält rund 100 Einträge zu Personalität und individuellen Unterschieden. Die Beiträge stammen von international führenden Psychologen. - Beschäftigt sich mit wichtigen klassischen und zeitgenössischen Modellen und Theorien der Persönlichkeitspsychologie, mit Mess- und Beurteilungsverfahren, Personalitätsprozessen und Unterschieden bei Individuen sowie mit Forschungsansätzen. - Bietet einen umfassenden und ausführlichen Überblick über die Persönlichkeitspsychologie. - The Encyclopedia of Personality and Individual Differences ist ein wichtiges Referenzwerk für Studenten der Psychologie und Fachexperten, die sich mit der Untersuchung und Erforschung von Persönlichkeit beschäftigen.
Few would dispute the truth of the statement `People are Different', but there is much controversy over why. This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary `nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package. The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears.
"A display of scientific courage and imagination." —William Saletan, New York Times Book Review Why do people—even identical twins reared in the same home—differ so much in personality? Armed with an inquiring mind and insights from evolutionary psychology, Judith Rich Harris sets out to solve the mystery of human individuality.
The book chapters cover different aspects of epilepsy genetics, starting with the "classical" concept of epilepsies as ion channel disorders. The second part of the book gives credit to the fact that by now non-ion channel genes are recognized as equally important causes of epilepsy. The concluding chapters are designed to offer the reader insight into current methods in epilepsy research. Each chapter is self-contained and deals with a selected topic of interest. - Authors are the leading experts in the field of epilepsy research - Book covers the most important aspects of epilepsy - Interesting for both scientists and clinicians
In this book, a geneticist who studies identical twins “treats the view that genes are destiny with skepticism” (The New York Times). How much are the things you choose to do every day determined by your genes and how much is your own free will? Drawing on his own cutting-edge research of identical twins, leading geneticist Tim Spector shows us how the same upbringing, the same environment, and even the same exact genes can lead to very different outcomes. Thought-provoking, entertaining, and enlightening, Identically Different helps us understand the science behind what makes each of us unique and so quintessentially human.