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Humanity has precipitated a planetary crisis of resource consumption—a crisis of stuff. So ingrained is our stuff-centric view that we can barely imagine a way out beyond substituting a new portmanteau of material things for the one we have today. In The Human Scaffold, anthropologist Josh Berson offers a new theory of adaptation to environmental change. Drawing on niche construction, evolutionary game theory, and the enactive view of cognition, Berson considers cases in the archaeology of adaptation in which technology in the conventional sense was virtually absent. Far from representing anomalies, these cases exemplify an enduring feature of human behavior that has implications for our own fate. The time has come to ask what the environmental crisis demands of us not as consumers but as biological beings. The Human Scaffold offers a starting point.
Humanity has precipitated a planetary crisis of resource consumption—a crisis of stuff. So ingrained is our stuff-centric view that we can barely imagine a way out beyond substituting a new portmanteau of material things for the one we have today. In The Human Scaffold, anthropologist Josh Berson offers a new theory of adaptation to environmental change. Drawing on niche construction, evolutionary game theory, and the enactive view of cognition, Berson considers cases in the archaeology of adaptation in which technology in the conventional sense was virtually absent. Far from representing anomalies, these cases exemplify an enduring feature of human behavior that has implications for our own fate. The time has come to ask what the environmental crisis demands of us not as consumers but as biological beings. The Human Scaffold offers a starting point.
Handbook of Tissue Engineering Scaffolds: Volume Two provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems.
Empirical and philosophical perspectives on scaffolding that highlight the role of temporal and temporary resources in development across concepts of culture, cognition, and evolution. "Scaffolding" is a concept that is becoming widely used across disciplines. This book investigates common threads in diverse applications of scaffolding, including theoretical biology, cognitive science, social theory, science and technology studies, and human development. Despite its widespread use, the concept of scaffolding is often given short shrift; the contributors to this volume, from a range of disciplines, offer a more fully developed analysis of scaffolding that highlights the role of temporal and temporary resources in development, broadly conceived, across concepts of culture, cognition, and evolution. The book emphasizes reproduction, repeated assembly, and entrenchment of heterogeneous relations, parts, and processes as a complement to neo-Darwinism in the developmentalist tradition of conceptualizing evolutionary change. After describing an integration of theoretical perspectives that can accommodate different levels of analysis and connect various methodologies, the book discusses multilevel organization; differences (and reciprocality) between individuals and institutions as units of analysis; and perspectives on development that span brains, careers, corporations, and cultural cycles. Contributors Colin Allen, Linnda R. Caporael, James Evans, Elihu M. Gerson, Simona Ginsburg, James R. Griesemer, Christophe Heintz, Eva Jablonka, Sanjay Joshi, Shu-Chen Li, Pamela Lyon, Sergio F. Martinez, Christopher J. May, Johann Peter Murmann, Stuart A. Newman, Jeffrey C. Schank, Iddo Tavory, Georg Theiner, Barbara Hoeberg Wimsatt, William C. Wimsatt
In Shakespeare's London, the stage of the playhouse, the stake of the bear baiting arena, and the scaffold of public execution constituted an ensemble of related spectacles that shared the same audiences. Andreas Höfele argues that this generated a powerful exchange of images and a spill-over of animal features into Shakespeare's characters.
Innovative, alternative account of romanticism, exploring how art and science together contested the evidentiary authority of the human body.
"This book creates the concept of “enterprise organization engineering” by introducing the paradigm of tissue engineering in life science into enterprise organization research. It regards the enterprise as live organization, which has life characters and ability to grow and self-repair. The authors seek origins from seven theories including human tissue engineering, evolutionary economics, organization theories, enterprise theories, entrepreneur theory, human recourse theory, knowledge management theory, and summarizes the research framework including five parts : research on enterprise life characteristics, enterprise genes, enterprise seed cells, enterprise life scaffolds and research on enterprise growth factors. This research framework, which bases on five principles, presents a new perspective for corporate management staff and riches management theories."
Handbook of Tissue Engineering Scaffolds: Volume Two provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems. - Dedicated to the specialist topic of composite scaffolds, featuring all human body systems - Covers basic fundamentals and advanced clinical applications - Includes up-to-date information on preparation methodology and characterization techniques - Highlights clinical data and case studies
Every day and in all parts of the world, humans experience different grades of wounding and tissue loss of the skin, thus initiating one of the most complex biological processes. Acute and chronic wounds, as well as the additional problem of skin scarring, involve not only great suffering for the patient but also extensive health care costs for the society. Although the wound-healing process is a wellstudied field much knowledge must be gained to unlock the door to regenerative pathways in humans. Epidermis heals by complete regeneration, but dermal and full thickness injuries heal with fibrosis and scar formation. In Papers I and II, we studied whether dermal scarring could be turned into regeneration by using two different types of threedimensional dermal scaffolds. In Paper I, we studied a solid scaffold made of poly(urethane urea), initially in vitro then followed by in vivo studies. In Paper II, we intradermally injected a liquid three-dimensional scaffold consisting of porous gelatin spheres in human healthy volunteers. Both materials showed ingrowth of functional fibroblasts and blood vessels and appeared to stimulate regeneration while slowly degrading. This finding could be of significant clinical importance, for example in burn wound care or after cancer surgery. In Papers III and IV, we wanted to study the effects of amniotic fluid and hyaluronic acid on adult wound healing, because early fetal wounds re-epithelialize rapidly and naturally heal dermis by regeneration without the need of a dermal scaffold. Amniotic fluid, naturally rich in hyaluronic acid, induced an accelerated reepithelialization of adult human wounds in vitro, and hyaluronic acid seemed to be important for this effect. Stimulation with exogenous hyaluronic acid in vivo induced accelerated re-epithelialization and an altered protein expression in healthy human volunteers. The inflammatory phase of wound healing, as measured by tissue viability imaging, was not affected by hyaluronic acid. Elucidating the effects of amniotic fluid and hyaluronic acid on the wound-healing process may allow improved treatment of wounds with impaired healing. Studies on finding new dermal scaffolds and studies on the positive effect of amniotic fluid or hyaluronic acid on the wound-healing process are two different ways of gaining insight that may lead to regeneration and improved wound healing for the patient.
Biomaterials are often designed to act as scaffolds, i.e., 3D porous templates that support and stimulate the growth of healthy tissue and then safely dissolve once they have performed their functions. This book provides a picture of the current state of the art in the field of scaffolds for tissue engineering, highlighting the potential associated to the latest scientific and technological advancements. The former part of the book focuses on the repair of "hard" tissues (primarily bone) by means of bioceramic/glass scaffolds, and the latter deals with the applications of polymeric scaffolds for regenerating "soft" tissues and structures including the peripheral nerve, heart, gastric mucosa and pancreas. Special emphasis is given to the challenges associated to scaffold manufacturing, biomimetic properties and cell-scaffold interactions.