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The variety of viewpoints expressed in this book illustrate the many contro versies surrounding MDMA [1]. On the one hand, the proponents ofMDMA use believe this agent offers a unique psychoactive effect that may have important clinical applications, especially in the field of psychotherapy. On the other hand, the scientific data concerning the neurotoxic effects of the drug are unequivocal. The most striking feature of the human information of MDMA is the paucity of data that has been generated on the drug since it was patented in 1914. As pointed out by Beck (Chapter 6) and others, a clear need exists for better epidemiological and clinical data on MDMA. In the absence of such data, arguments both for and against the cotinued use ofMDMA with humans will be difficult to support. Unfortunately, the currently available data must be used to develop rational policies for potential human users of MDMA. At the present time, there are no data indicating that recreational doses of MDMA permanently damage the human brain. Nonetheless, based on a review of the contents of this book as well as on informal discussions with approximately 200 recreational users of MDMA, the following personal observations suggest that MDMA is radically different from other recreational drugs.
Written by the world's leading experts on MDMA, "Ecstasy: The Complete Guide" takes the first unbiased look at the risks and the benefits of this unique drug, including the science of how it works; its promise as a treatment for depression, post-traumatic stress disorders, and other mental illnesses; and how to minimize the risks of use.
From its first publication in 1997, Altered State established itself as the definitive text on Ecstasy and dance culture. This new edition sees Matthew Collin cast a fresh eye on the heady events of the acid house 'Summer of Love' and the rave scene's euphoric escalation into commercial excess as MDMA became a mass-market narcotic. Altered State is the best-selling book on Ecstasy culture, using a cast of memorable characters to track the origins of the scene and its drug through psychedelic subcults, underground gay discos and the Balearic paradise of Ibiza, to the point where Tony Blair was using an Ecstasy anthem as an election campaign song. Altered State critically examines the ideologies and myths of the scene, documenting the criminal underside to the blissed-out image, shedding new light on the social history of the most spectacular youth movement of the twentieth century.
The history of ecstasy, its discovery and use and social implications.
The Psychopharmacology of Hallucinogens focuses on the properties, compositions, functions, transformations, and reactions of hallucinogens. The selection first offers information on the biosynthesis and action of hallucinogens in mammals; role of biogenic amines in the actions of monomethoxy-amphetamines; and molecular mechanism of action of hallucinogens. The book then takes a look at the molecular determinants for interaction with the LSD receptor, including biological studies, molecular reactivity, and summation of the molecular polarization complexes. The text examines the progress on the development of a receptor model for hallucinogenic amphetamines; characterization of psychotomimetics; physical identification of hallucinogenic compounds; and aspects of the pharmacology of phencyclidine. The book also underscores the effects of LSD, mescaline, and DMT, including effects on humans, proposed model, and effects of monoamine manipulations. The text also presents analysis of hallucinogens by Pavlovian conditioning, behavioral measures of hallucinogenic behavior, and drug model of hallucinosis. The selection is a dependable reference for readers interested in the study of hallucinogens.
As recent statistics show, more than 100 million people on the planet have used MDMA. After cannabis, it is the second most used drug worldwide. Yet there are many misconceptions surrounding the drug, which have affected attempts to use it as a legitimate and highly effective therapeutic aid. Despite the enormous extent of its use, and abuse, MDMA produced neither a large number of medical complications nor social harm on a larger scale, and has very limited addictive potential. In The History of MDMA, Torsten Passie aims to explore a deeper and more differentiated understanding of MDMA and its history. He has conducted personal interviews with most of the people significant in the history of MDMA and provides a lot of new material to present the first comprehensive overview of the history of MDMA in Europe and the U.S. This not just as it is perceived in the public mind, but also in terms of its history as an underground drug, the research into it, political responses to it, its spread, and its medical use. Passie brings these multiple narratives and levels of its history and their complex interactions together in order to make this book an essential reading for anyone interested in the topic.
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Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. - A comprehensive reference on the effects of drug addiction on the human nervous system - Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs - Includes foundational science chapters on the biology of addiction - Details challenges in diagnosis and treatment options
A Brief History of the Netherlands, Second Edition provides a clear, lively, and comprehensive account of the history of the Netherlands from ancient times to the present day. It relates the central events that have shaped the country and details their significance in historical context, touching on all aspects of the history of the country, from political, international, and economic affairs to cultural and social developments. Illustrated with full-color maps and photographs, and accompanied by a chronology, bibliography, and suggested reading, this accessible overview is ideal for the general reader. Coverage includes: From Early Settlements to Frankish Rule Political Strife and the Rise of Urban Life Wars of Religion and Emancipation Resplendent Republic Dynamo in Decline From Republic to Empire to Kingdom Building the Modern Nation-State Neutrality, Depression, and World War Reconstruction and Rebirth after World War II The Netherlands in the Twenty-first Century: the Triumphs and Trials of a Tolerant Society
Emerging illicit drugs pose a significant clinical challenge. This handbook offers an engaging, concise guide to managing these challenges.