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Bacteria are among the earliest forms of life on Earth. Notwithstanding their small size and primitive origin, bacteria still have a tremendous impact on everyday human life. Over the centuries, research into bacteria have provided and enriched the fundamental biological knowledge due to their readily measured processes and effects on higher organisms. Although molecular genetics and microbiology were among the scientific fields that have mostly benefited from the discoveries made in bacteria, our current state of knowledge has gone beyond what anyone could have ever imagined. The present Research Topic aims to cover new and exciting broad aspects of the importance of bacteria to human life, both positive and negative influences. Regulation of bacterial gene expression, replication and segregation control mechanisms, cell to cell communication via quorum sensors, and the relatively recent finding of bacterial immunity via CRISPR, have led to the development of many, and very important new tools in biotechnology and the emerging field of molecular medicine. The battle against infectious diseases has also benefited from the genetic approaches that have been developed in the quest for finding new targets and novel drugs against pathogenic bacteria. At the next level, the human microbiome project has opened up new avenues in understanding the role of bacteria in human health and wellbeing. Finally, the relationship between bacterial infections and human cancers will also be covered, a subject that is still under verification through rigorous experimental approaches. Special emphasis will be given to the bacterial accessory genome, i.e the mobilome, as the primary cause of health-threatening antimicrobial resistance and the production of toxins and virulence factors. Taking into account the evolutionary importance of horizontal gene transfer and the additional beneficial roles of certain bacterial mobile genetic elements, they help project best “the Good, the Bad and the Ugly” outline of this topic. At the time this eBook is about to be published, our Research Topic has registered nearly 55, 000 views.
The use of nanotechnologies continues to grow, as nanomaterials have proven their versatility and use in many different fields and industries within the scientific profession. Using nanotechnology, materials can be made lighter, more durable, more reactive, and more efficient leading nanoscale materials to enhance many everyday products and processes. With many different sizes, shapes, and internal structures, the applications are endless. These uses range from pharmaceutics to materials such as cement or cloth, electronics, environmental sustainability, and more. Therefore, there has been a recent surge of research focused on the synthesis and characterizations of these nanomaterials to better understand how they can be used, their applications, and the many different types. The Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials seeks to address not only how nanomaterials are created, used, or characterized, but also to apply this knowledge to the multidimensional industries, fields, and applications of nanomaterials and nanoscience. This includes topics such as both natural and manmade nanomaterials; the size, shape, reactivity, and other essential characteristics of nanomaterials; challenges and potential effects of using nanomaterials; and the advantages of nanomaterials with multidisciplinary uses. This book is ideally designed for researchers, engineers, practitioners, industrialists, educators, strategists, policymakers, scientists, and students working in fields that include materials engineering, engineering science, nanotechnology, biotechnology, microbiology, drug design and delivery, medicine, and more.
This comprehensive book explores both the fundamental and practical aspects of microbial genetics, shedding light on viroids, viruses, phytoplasma, bacteria, fungi, and protozoa. Unveiling a fresh perspective, the book tackles traditional taxonomical debates by embracing DNA-based taxonomy, offering a novel approach to understanding phylogeny within this microbe realm. Furthermore, it delves into the exciting realm of metagenomics, revolutionizing the identification and classification of unculturable microorganisms. Written by leading experts, this essential reading material caters to students and researchers in Microbiology, Genetics, and Biotechnology.
The textile industry is focused in its search for alternative green fibres with the aim of providing high-quality products which are fully recyclable and biodegradable. Natural textile materials from renewable sources play an increasingly important role in the industry due to their unique properties and functionality over synthetic fibres, as well as their sustainability. Antimicrobial Textiles from Natural Resources is an in-depth guide to the latest methods and applications of natural antimicrobial materials. A broad range of applications are addressed, from common to specialized applications, including many in the biomedical sector. This world-class collection of contributors write from a range of disciplinary backgrounds, providing important insights from textile science and technology, materials science, chemical engineering, and biomedical engineering. Advice and proposed solutions are presented in a rigorous and practical way, drawing on results and case studies obtained from academic and industrial laboratories worldwide. - Examines how natural fibres can be used in the place of less renewable or sustainable choices, thus helping designers improve the sustainability of their products - Provides unique coverage of the biofunctionality of biopolymers in textiles - Explains how antimicrobial properties can reduce odour, extend the life of textiles, and provide numerous medical benefits
Metal ions are fundamental elements for the maintenance of the lifespan of plants, animals and humans. Their substantial role in biological systems was recognized a long time ago. They are essential for the maintenance of life and their absence can cause growth disorders, severe malfunction, carcinogenesis or death. They are protagonists as macro- or microelements in several structural and functional roles, participating in many bio-chemical reactions, and arise in several forms. They participate in intra- and intercellular communications, in maintaining electrical charges and osmotic pressure, in photosynthesis and electron transfer processes, in the maintenance of pairing, stacking and the stability of nucleotide bases and also in the regulation of DNA transcription. They contribute to the proper functioning of nerve cells, muscle cells, the brain and the heart, the transport of oxygen and to many other biological processes up to the point that we cannot even imagine a life without metals. In this book, the papers published in the Special Issue “The Role of Metal Ions in Biology, Biochemistry and Medicine” are summarized, providing a picture of metal ion uses in biology, biochemistry and medicine, but also pointing out the toxicity impacts on plants, animals, humans and the environment.
The goal of Molecules, Microbes, and Meals is to provide an overview of the science of food, exploring all aspects of how food products we purchase and consume come to have the characteristics they do. The key focus is on the science underpinning the appearance, flavor, texture and qualities of food, and the transformations that occur when we cook food products. Every food product is a highly complex scientific entity, and a key objective of the book is to show that an understanding of the science of food can enhance our appreciation and wonder at it. Another key theme will be the convergence of science and art in food, and the history of food, whereby we have known how to undertake what are exceptionally scientifically complex activities such as fermentation, pasteurization and cooking long before the scientific basis for what was happening was understood.
This book offers a unique perspective on the invisible organ, a body part that has been visualized only recently. It guides the readers into the world of the microbial constituents that make humans the way they are. The vitamins they produce, the smell they generate, the signals they create, and the molecular guards they elaborate are some of the benefits they bestow on humans. After introducing the notion as to why microbes are an integral component in the development of humans, the book examines the genesis of the microbiome and describes how the resident bacteria work in partnership with the skin, digestive tract, sexual organs, mouth and lungs to execute vital physiological functions. It then discusses the diseases that are triggered by the disruption of the harmonious relationships amongst these diverse systems and provides microbial cures to ailments such as obesity and digestive complications. Finally, the book focuses on the future when the workings of the human microbes will be fully unravelled. Societal changes in health education, the establishment of the microbiome bank, the fight against hunger, space travel, designer traits and enhanced security are explained. Each chapter is accompanied by captivating illustrations and ends with a visual summary. Dr. Appanna has been researching for over 30 years on various aspects of microbial and human cellular systems. He is a professor of biochemistry and has also served as Department Chair and Dean of the Faculty at Laurentian University, Sudbury, Canada. The book is aimed at readers enrolled in medical, chiropractic, nursing, pharmacy, and health science programs. Practicing health-care professionals and continuing education learners will also find the content beneficial.
The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.
A page-turning novel that is also an exploration of the great philosophical concepts of Western thought, Jostein Gaarder's Sophie's World has fired the imagination of readers all over the world, with more than twenty million copies in print. One day fourteen-year-old Sophie Amundsen comes home from school to find in her mailbox two notes, with one question on each: "Who are you?" and "Where does the world come from?" From that irresistible beginning, Sophie becomes obsessed with questions that take her far beyond what she knows of her Norwegian village. Through those letters, she enrolls in a kind of correspondence course, covering Socrates to Sartre, with a mysterious philosopher, while receiving letters addressed to another girl. Who is Hilde? And why does her mail keep turning up? To unravel this riddle, Sophie must use the philosophy she is learning—but the truth turns out to be far more complicated than she could have imagined.