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The Foundations of Genetics describes the historical development of genetics with emphasis on the contributions to advancing genetical knowledge and the various applications of genetics. The book reviews the work of Gregor Mendel, his Law of Segregation, and of Ernst Haeckel who suggested that the nucleus is that part of the cell that is responsible for heredity. The text also describes the studies of W. Johannsen on "pure lines," and his introduction of the terms gene, genotype, and phenotype. The book explains the theory of the gene and the notion that hereditary particles are borne by the chromosomes (Sutton-Boveri hypothesis). Of the constituent parts of the nucleus only the chromatin material divides at mitosis and segregates during maturation. Following studies confirm that the chromatin material, present in the form of chromosomes with a constant and characteristic number and appearance for each species, is indeed the hereditary material. The book describes how Muller in 1927, showed that high precision energy radiation is the external cause to mutation in the gene itself if one allele can mutate without affecting its partner. The superstructure of genetics built upon the foundations of Mendelism has many applications including cytogenetics, polyploidy, human genetics, eugenics, plant breeding, radiation genetics, and the evolution theory. The book can be useful to academicians and investigators in the fields of genetics such as biochemical, biometrical, microbial, and pharmacogenetics. Students in agriculture, anthropology, botany, medicine, sociology, veterinary medicine, and zoology should add this text to their list of primary reading materials.
A definitive account of the origins of modern mathematical population genetics, first published in 2000.
An accessible but rigorous treatment of the theoretical foundations of population genetics. Population genetics—the branch of evolutionary biology concerned with understanding how and why populations’ genetic compositions change over time—rests on a well-developed theoretical foundation that draws on genetics, mathematics, and computer science. This textbook provides an approachable but rigorous treatment for advanced undergraduate and graduate students interested in building a quantitative understanding of the genetics of evolution. Existing texts either assume very mathematically advanced readers, or avoid much of the underlying theory, instead focusing on current methods of data analysis. In contrast, The Foundations of Population Genetics develops the theory from first principles. Requiring only confidence in algebra, this self-contained, student-friendly book illustrates the conceptual framework, terminology, and methods of mathematical modeling. It progressively introduces concepts from genetics as needed, while emphasizing biological implications throughout. As a result, readers come away with a deep understanding of the structure of population genetics without needing to master its mathematics. Connects theory with the most recent genetic data better than existing texts Features engaging real-world examples and extensive original figures Provides dozens of carefully scaffolded questions that deepen the reader's understanding of key concepts Ideal as a succinct reference for established scientists in biology, medicine, and computer science Instructor resources available
In the small “Fly Room†at Columbia University, T.H. Morgan and his students, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written in 1965 by one of those present at the beginning. His account is one of the few authoritative, analytic works on the early history of genetics. This attractive reprint is accompanied by a website, http://www.esp.org/books/sturt/history/ offering full-text versions of the key papers discussed in the book, including the world's first genetic map.
This book makes Moore's wisdom available to students in a lively, richly illustrated account of the history and workings of life. Employing rhetoric strategies including case histories, hypotheses and deductions, and chronological narrative, it provides both a cultural history of biology and an introduction to the procedures and values of science.
Genetics Made Easy is not just a book; it's a journey into the heart of what makes us who we are. Written with the non-scientist in mind, it offers a refreshing approach to understanding the complex world of genetics. From the spirals of DNA to the marvels of gene editing, this book unfolds the mysteries of genetics with clarity, simplicity, and profound insight. Dive into the Chapters: The Alphabet of Life: DNA - Begin your journey with the basic building blocks of life, learning how DNA forms the script of our existence. Reading the Genetic Script: From DNA to Traits - Discover how genetic information is translated into the traits that define every organism. Blueprints and Architects: Genetics in Development - Explore the role of genetics in development and how it shapes organisms from conception to maturity. Genetic Editors: Mutation and Variation - Understand the mechanisms behind genetic mutations and the importance of variation for survival and evolution. Interwoven Destinies: Epigenetics and Environment - Delve into the interplay between genetics and the environment, and how external factors can influence gene expression. The Librarian's Code: Genetic Inheritance - Unravel the complexities of genetic inheritance and how traits are passed down through generations. Molecular Scissors: The Revolution of CRISPR - Get acquainted with CRISPR, the groundbreaking gene-editing technology that is reshaping the future of medicine and biology. The Future of Genetics: Ethics and Possibilities - Reflect on the ethical considerations and the vast potential that genetic research holds for humanity. Introduction to Genetics Made Easy: Embark on an enlightening expedition through the world of genetics, where complex concepts are made accessible through vivid examples, engaging analogies, and compelling explanations. This book is designed to clear the fog that often surrounds genetic science, illuminating each topic with the clarity of the morning sun. "Genetics Made Easy" is crafted for anyone eager to understand the language of life, whether you're a student, a professional in the medical or biotech fields, or simply curious about the genetic codes that write our existence. With a narrative as warm and inviting as a conversation with a friend, this book promises to open your mind and stir your sense of wonder. Why You Need This Book: For clarity: If genetics has always seemed like a dense forest of acronyms and abstract theories, this book is your path to understanding. For curiosity: Feed your curiosity about how life is written and rewritten at the molecular level. For appreciation: Gain a deeper appreciation for the intricate dance of nature's elements that weave the fabric of life. Takeaway: "Genetics Made Easy" invites you on an adventure into the genetic universe, promising not just knowledge but a profound appreciation for the beauty and complexity of life. Your journey into genetics starts now, and it promises to be as thrilling as it is enlightening. Welcome aboard.