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Forensic Pharmacology explores the many links between drugs and forensic science, from drug-induced violence and crime to determining whether a person taking a certain medication is capable of standing trial for a crime, to the forgery of prescriptions. The reader is introduced to the daily work of the scientists, and the principles of pharmacology and toxicology, as well as the various classes and technical analysis of drugs of abuse.
The Handbook of Forensic Drug Analysis is a comprehensive chemical and analytic reference for the forensic analysis of illicit drugs. With chapters written by leading researchers in the field, the book provides in-depth, up-to-date methods and results of forensic drug analyses. This Handbook discusses various forms of the drug as well as the origin and nature of samples. It explains how to perform various tests, the use of best practices, and the analysis of results. Numerous forensic and chemical analytic techniques are covered including immunoassay, gas chromatography, and mass spectrometry. Topics range from the use of immunoassay technologies for drugs-of-abuse testing, to methods of forensic analysis for cannabis, hallucinogens, cocaine, opioids, and amphetamine. The book also looks at synthetic methods and law enforcement concerns regarding the manufacture of illicit drugs, with an emphasis on clandestine methamphetamine production. This Handbook should serve as a widely used reference for forensic scientists, toxicologists, pharmacologists, drug companies, and professionals working in toxicology testing labs, libraries, and poison control centers. It may also be used by chemists, physicians and those in legal and regulatory professions, and students of graduate courses in forensic science. - Contributed to by leading scientists from around the world - The only analysis book dedicated to illicit drugs of abuse - Comprehensive coverage of sampling methods and various forms of analysis
A comprehensive review of the science of drug testing in all its aspects, placing emphasis on technologies that use body fluids other than urine for determining the presence of drugs of abuse. The authors discuss the various body fluid specimens suitable for testing for illicit drugs-particularly saliva, sweat, and hair-describe the structural and manufacturing aspects of on-site testing devices based on lateral flow immunoassay, and detail the pitfalls of using these specimens. They also discuss in detail the problem of sample adulteration and its detection. Since oral fluid has the best potential of succeeding urine as the next matrix of choice for drug detection, four popular saliva testing devices are examined: Intercept®, the Drager Drug Test®, Oratect®, and Drugwipe. Political, social, and legal issues are also considered in articles on privacy, the use of drug testing in courts, and the problem of sample adulteration.
This book provides a broad reference covering important drugs of abuse including amphetamines, opiates, and steroids. It also covers psychoactive plants such as caffeine, peyote, and psilocybin. It provides chemical structures, analytical methods, clinical features, and treatments of these drugs of abuse, serving as a highly useful, in-depth supplement to a general medical toxicology book. The style allows for the easy application of the contents to searchable databases and other electronic products, making this an essential resource for practitioners in medical toxicology, industrial hygiene, occupational medicine, pharmaceuticals, environmental organizations, pathology, and related fields.
A well structured reference work reviewing the five main classes of drugs of abuse that figure prominently in forensic work: alcohol, the benzodiazepines, the opioids including heroin, the stimulants including amphetamines and cocaine, and cannabis. It begins with an introduction to drug classes, a practical guide to specimen collection, explanation of pharmacokinetic concepts and measurements, techniques used to analyse drugs and the importance of the concepts of tolerance and dependence analysis. There are then seven sections for each drug class covering nomenclature and source (legal and illegal), pharmacokinetics and metabolism, analytical methods for detection in biological fluids, expected and adverse effects in humans, issues of tolerance and dependence, and finally toxicology.
Provides a self-teaching reference text for forensic chemistry laboratories and law enforcement agencies world-wide. The text includes sections on the importance of physical examinations of drugs and their wrappings; and the use of gas and high-performance chromatography.
New designer drugs, access to databases, and changing availability of samples for analysis have changed the face of modern forensic toxicology in recent years. Forensic Toxicology: Drug Use and Misuse brings together the latest information direct from experts in each sub-field of the discipline providing a broad overview of current thinking and the most innovative approaches to case studies. The text begins with an in-depth discussion of pharmaco­epidemiology, including information on the value of nationwide databases in forensic toxicology. The use and abuse of drugs in driving, sport and the workplace are then discussed by industry experts who are conducting case work in their field. Not only are new drug groups discussed (NPS), but also their constantly changing impact on drug legislation. Synthetic cannabinoids, khat and mephodrone are discussed in detail. Following a section devoted to legislation and defence, readers will find comprehensive chapters covering sample choice reflecting the increasing use of hair and oral fluid, and also the less commonly used sweat and nail analysis. New and old case examples are compared and contrasted in the final part of the book, which will enable readers to understand how drugs impact on each other and how the interpretative outcome of a case are dependent on many aspects. From use of pharmaceutical drugs in a clinical setting, through smart drugs to new psychoactive drugs, this book documents the wide range in which drugs today are abused. This book will be an essential resource for postgraduate students in forensic toxicology, and for researchers in forensic toxicology laboratories who need the latest data and knowledge.
AUTHORITATIVE INFORMATION FROM THE SOURCE YOU TRUST The third edition of Karch's Pathology of Drug Abuse continues to provide a comprehensive yet accessible guide to the pathology, toxicology, and pharmacology of commonly abused drugs. As in previous editions, the focus remains on the investigation of drug-related deaths and on practical app
This invaluable textbook, written by international experts, covers all the main elements of forensic toxicology and analytical toxicology techniques as well as the important parts of pharmacokinetics, drug metabolism, and pharmacology in general, with a particular focus on drugs of abuse.
Forensic Pharmacology offers a unique and comprehensible account of pharmacological methods and knowledge, and how to use them to solve problems in crimes from drunken driving to murder. It also deals with negligence in giving drugs, and adverse reactions to drugs. The text is enlivened by cases from the literature and from the authors' experience. Appendices give detailed examples of pharmacological problems and their solutions; tables and equations for alcohol calculations; and data for medicines encountered in forensic work. Experts do not always understand what lawyers want of them, and lawyers fail to appreciate that experts in medicine and pharmacology may not be experts in the law. The section entitled 'legal considerations' was written by a barrister with wide experience of using expert evidence and explains clearly the legal principles. It also contains some helpful hints on how to deal with court procedure and adversarial lawyers.