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Stem cells, particularly pluripotent stem cells, hold significant promise for developing therapies for diseases and disorders for which there are no current treatments and for regenerating human cells, tissues, and possibly even organs. However, to be able to translate stem cell research into therapies, researchers must first address many scientific, ethical, and regulatory hurdles. The need for researchers and sponsors to demonstrate progress and the hopes of patient groups for new therapies have pressured researchers to move quickly into clinical trials and encouraged the opening of clinics offering unproven and unapproved stem cell treatments. This book tells the story of the development of the field, and identifies the ethical issues and challenges stem cell translation raises. It will be of interest to ethicists, scientists, and regulators working in the stem cell field, as well as the general reader following scientific developments.
In this timely collection, some of the world's leading ethicists grapple with the variety of issues posed by human embryonic stem cell research. Investigates the moral status of the embryo including the creation of chimeras and paying for gametes (eggs and sperm) and embryos for research purposes Provides a thorough evaluation of the ethics and politics of regulating hESC research, and the privacy, confidentiality, and informed consent in the conduct of research and clinical investigations Essential reading for scientists, philosophers, policy makers, and all who are interested in the ethical conduct of science Contributors include David DeGrazia, Lori Gruen, Elizabeth Harman, John Harris, Jeff McMahan, Don Marquis and Peter Singer
While many believe stem cell research holds the key to curing a wide range of ailments, others see this research as opening a Pandora’s box that will devalue human life. In Stem Cell Now, Christopher Scott—executive director of Stanford University’s Stem Cells and Society Program—lays out the scientific and ethical issues surrounding this national dilemma. Scott guides readers through the latest advances in stem cell research in clear, accessible language, telling the stories of the researchers who are exploring the potential of stem cells to cure cancer, grow new organs, and repair the immune system. He also leads readers through a discussion of the question at the heart of the explosive ethical debate: How, as a society, do we balance our responsibilities to the unborn and the sick? Stem Cell Now is essential reading for anyone who wants to build an informed opinion on stem cell research.
Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
The Answer to Your Health Problems IS NOT WHAT YOU EXPECT What is adult stem cell therapy? Are there different adult stem cell treatment options? What type of conditions does adult stem cell therapy treat? What is the success rate? How much does it cost? Are there any risks or side effects? What's so great about adult stem cell therapy? Joseph "Dr. Joe" Christiano clears away the confusion surrounding this groundbreaking new treatment. Discover how stem cell activators target adult stem cells to reverse twenty-six conditions that may be adversely affecting your health. IT'S TIME TO JOIN THE REVOLUTION!
Stem Cells: An Insider's Guide is an exciting new book that takes readers inside the world of stem cells guided by international stem cell expert, Dr. Paul Knoepfler. Stem cells are catalyzing a revolution in medicine. The book also tackles the exciting and hotly debated area of stem cell treatments that are capturing the public's imagination. In the future they may also transform how we age and reproduce. However, there are serious risks and ethical challenges, too. The author's goal with this insider's guide is to give readers the information needed to distinguish between the ubiquitous hype and legitimate hope found throughout the stem cell world. The book answers the most common questions that people have about stem cells. Can stem cells help my family with a serious medical problem such as Alzheimer's, Multiple Sclerosis, or Autism? Are such treatments safe? Can stem cells make me look younger or even literally stay physically young? These questions and many more are answered here.A number of ethical issues related to stem cells that spark debates are discussed, including risky treatments, cloning and embryonic stem cells. The author breaks new ground in a number of ways such as by suggesting reforms to the FDA, providing a new theory of aging based on stem cells, and including a revolutionary Stem Cell Patient Bill of Rights. More generally, the book is your guide to where the stem cell field will be in the near future as well as a thoughtful perspective on how stem cell therapies will ultimately change your life and our world.
Chapters Chapter 1: Exploring the Nexus of Biotechnology and Psychopharmacology to treat mental disorder by concentration on substance use disorder Chapter 2: Biotechnology and Pharmacology: A Powerful Confluence of Science and Medicine Chapter 3: Bioinformatics and Computational Biology: Unraveling Biological Complexity Chapter 4: Bioprocessing and Biomanufacturing: Engineering the Future of Drug Production Chapter 5: Targeted Drug Delivery: Innovations in Nanotechnology and Drug Carriers Chapter 6: Biomarkers: The Key to Precision Diagnosis and Treatment Chapter 7: Regenerative Medicine: Harnessing the Power of Cellular and Tissue Engineering Chapter 8: Gene Editing and CRISPR Technology: Rewriting the Possibilities in Disease Treatment Chapter 9: Monoclonal Antibodies: Engineered Warriors against Disease Chapter 10: Unlocking the Genetic Code: Genomics and Personalized Medicine
#1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.
By the middle of the 21st century century we can expect that the rapid progress in biotechnology will utterly transform human life. Even the prospect of immortality beckons. Such scenarios excite many people and frighten or appall many others--already biotechnology opponents are organizing political movements aimed at restricting scientific research, banning the development and commercialization of various products and technologies, and limiting citizens' access to the fruits of the biotech revolution. Bailey, science writer for Reason magazine, argues that the coming biotechnology revolution, far from endangering human dignity, will enable more of us to live flourishing lives free of disease, disability, and the threat of early death. Bailey covers the full range of the coming biotechnology breakthroughs, from stem-cell research to third-world farming, from brain-enhancing neuropharmaceuticals to designer babies.--From publisher description.
Identifies ethical issues and requirements of genetically-based addiction research, specifies the ethical and public policy implications of applying research.