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The fundamental logic arguments of organic chemistry are emphasized in this book. Resonance effects, inductive effects and steric effects are used to explain most of the common types of organic reactions. Arrow pushing and mechanism are presented with each type of reaction, most of which utilize nucleophile and electrophile chemistry. Only two free radical reactions are presented (sp3 C-H substitution and HBr addition to alkenes). Limited examples are chosen for each 'typical' type of reaction covered in the year-long course, rather than comprehensive coverage, that often overwhelms beginning students. The book is only about a third the size of most current organic textbooks. It is also "self published" in order to keep the cost to a minimum. That means I am not only the author, I am also the editor. If you decide to use this book, you immediately become my co-editor. Let me know when you find any inevitable errors (thanks!). This book represents my 40 years of teaching organic chemistry and my hope that it makes organic chemistry 'understandable'. Enjoy the journey.
This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.
Intended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and "common error alerts" are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set.
Uses hands-on demonstrations with familiar materials to illustrate the concepts of chemistry in terms of everyday experience. The original edition was selected as an Outstanding Academic Title by the American Library Association.
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Explains the basic principles of organic chemistry and provides help with reactions, synthesis, mechanisms, spectra, reagents, and study methods.
Up-To-Date Coverage of Every Aspect of Commercial Aviation Safety Completely revised edition to fully align with current U.S. and international regulations, this hands-on resource clearly explains the principles and practices of commercial aviation safety—from accident investigations to Safety Management Systems. Commercial Aviation Safety, Sixth Edition, delivers authoritative information on today's risk management on the ground and in the air. The book offers the latest procedures, flight technologies, and accident statistics. You will learn about new and evolving challenges, such as lasers, drones (unmanned aerial vehicles), cyberattacks, aircraft icing, and software bugs. Chapter outlines, review questions, and real-world incident examples are featured throughout. Coverage includes: • ICAO, FAA, EPA, TSA, and OSHA regulations • NTSB and ICAO accident investigation processes • Recording and reporting of safety data • U.S. and international aviation accident statistics • Accident causation models • The Human Factors Analysis and Classification System (HFACS) • Crew Resource Management (CRM) and Threat and Error Management (TEM) • Aviation Safety Reporting System (ASRS) and Flight Data Monitoring (FDM) • Aircraft and air traffic control technologies and safety systems • Airport safety, including runway incursions • Aviation security, including the threats of intentional harm and terrorism • International and U.S. Aviation Safety Management Systems
K.C. Nicolaou - Winner of the Nemitsas Prize 2014 in Chemistry Here, the best-selling author and renowned researcher, K. C. Nicolaou, presents around 40 natural products that all have an enormous impact on our everyday life. Printed in full color throughout with a host of pictures, this book is written in the author's very enjoyable and distinct style, such that each chapter is full of interesting and entertaining information on the facts, stories and people behind the scenes. Molecules covered span the healthy and useful, as well as the much-needed and extremely toxic, including Aspirin, urea, camphor, morphine, strychnine, penicillin, vitamin B12, Taxol, Brevetoxin and quinine. A veritable pleasure to read.