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In ten years’ time, will antibiotics still work? Have we let bacteria get the upper hand in the evolutionary arms race? In the 1920s the discovery of the antibiotic penicillin started a golden age of medicine. However, experts warn that the end of that age may be just a decade away. In this BWB Text, microbiologist Siouxsie Wiles explores the looming crisis of antibiotic resistance and its threat to New Zealand. Wiles concludes that New Zealand must do more to protect the public from a future without antibiotics.
Argues that the pace of medical discoveries has slowed in the last twenty-five years due to excessive emphasis on the social and political aspects of health care, and to controversies caused by ethical issues.
Proposes a radically reconfigured medical model centered on mind-body interaction.
A contemporary exploration of death and dying by a young Duke Fellow who investigates the hows, whys, wheres, and whens of modern death and their cultural significance.
The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma. As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.
A look at fifteen popular medical treatments that have been shown to be far more harmful than helpful, yet are still recommended by doctors. Modern medicine has made major advances in the last few decades, as more informed practices, thorough research, and incredible breakthroughs have made it possible to successfully treat and even eradicate many serious ailments. But we still rely on medical interventions that are vastly out of date and can adversely affect our health. In Overkill, Dr. Paul a Offit debunks fifteen common medical interventions that continue despite mounting evidence they are damaging or even deadly. Discussing everything from vitamins, sunscreen, and eyedrops for pinkeye to more serious procedures like heart stent placement and knee surgery, Offit—an acclaimed medical expert and patient advocate—tears down prolific medical propaganda that, for decades, has been causing more harm than good. Analyzing the history of how these practices came to be, the biology of what makes them so ineffective, and the medical culture that has consistently turned a blind eye, Overkill seeks to move the needle far away from these counterproductive treatments—and help patients advocate for their health. By educating ourselves, we can ask better questions and bring a much-needed skepticism to some of the drugs and surgeries that are too readily available—and too heavily promoted.
At the dawn of the twenty-first century, we have become accustomed to medical breakthroughs and conditioned to assume that, regardless of illnesses, doctors almost certainly will be able to help—not just by diagnosing us and alleviating our pain, but by actually treating or even curing diseases, and significantly improving our lives. For most of human history, however, that was far from the case, as veteran medical historian Michael Bliss explains in The Making of Modern Medicine. Focusing on a few key moments in the transformation of medical care, Bliss reveals the way that new discoveries and new approaches led doctors and patients alike to discard fatalism and their traditional religious acceptance of suffering in favor of a new faith in health care and in the capacity of doctors to treat disease. He takes readers in his account to three turning points—a devastating smallpox outbreak in Montreal in 1885, the founding of the Johns Hopkins Hospital and Medical School, and the discovery of insulin—and recounts the lives of three crucial figures—researcher Frederick Banting, surgeon Harvey Cushing, and physician William Osler—turning medical history into a fascinating story of dedication and discovery. Compact and compelling, this searching history vividly depicts and explains the emergence of modern medicine—and, in a provocative epilogue, outlines the paradoxes and confusions underlying our contemporary understanding of disease, death, and life itself.
The End of Modern Medicine chronicles the work of a small, influential band of medical theorists and clinicians who over the past decade have sought to redress the physical fundamentalism of the biomedical model that shaped their professional training. Laurence Foss challenges the prevailing medical model whereby mind and body are essentially separated, and charts a new "psychobiological" course. Asking fresh questions, raising new possibilities, probing long-established preconceptions, Foss presents a radically reconfigured medical model. This model accounts for the full range of findings in the experimental literature, most notably those surfacing over the past quarter century in psychophysiological studies which show a correlation between psychosocial variables and disease susceptibility that are in line with what more basic sciences tell us about the behavior of material systems and the nature of scientific explanation. Foss also critically analyzes the regulative ideals of today's medical research community and puts modern science itself, from which these ideals derive, under a microscope.
The National Strategy for Combating Antibiotic Resistant Bacteria, published in 2014, sets out a plan for government work to mitigate the emergence and spread of resistant bacteria. Direction on the implementation of this strategy is provided in five-year national action plans, the first covering 2015 to 2020, and the second covering 2020 to 2025. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine evaluates progress made against the national strategy. This report discusses ways to improve detection of resistant infections and estimate the risk to human health from environmental sources of resistance. In addition, the report considers the effect of agricultural practices on human and animal health and animal welfare and ways these practices could be improved, and advises on key drugs and diseases for which animal-specific test breakpoints are needed.
Much of the improved survival rate from heart attack can be traced to Eugene Braunwald's work. He proved that myocardial infarction was an hours-long dynamic process which could be altered by treatment. Thomas H. Lee tells the life story of a physician whose activist approach transformed not just cardiology but the culture of American medicine.