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The first book of Poetry by multi-faceted artist and singer-songwriter, Jessika Bat. These poems span the years of her adolescence and young adulthood touching themes such as mythology, coming of age, love, sexuality, substance abuse, mother-daughter relationships, magic realism, and magical creatures
Progress in molecular and cellular biology has greatly enhanced our ability to accurately diagnose diseases that are caused by gene mutations, changes in genome structures, and altered gene expression; increased emphasis is now placed on translational research and the clinical treatment of these genetically determined diseases. Seeking Cures outlines the progress and implications of science's quest to identify therapeutic targets and initiate novel treatments at the gene, RNA, protein, and physiological levels. Also considered are aspects of treatment at the cellular level (e.g., those with hematopoietic stem cells or induced pluripotent stem cells). Topics covered in this text include: · outline of the processes typical for identifying disease-modifying therapies · examples of newer therapeutic approaches in use or under investigation to treat lysosomal storage diseases, inborn errors of metabolism, mitochondrial functional defects, and specific monogenic diseases · therapeutic designs for specific complex common diseases, including Alzheimer's disease, cancer, and autism Through these specific examples, Seeking Cures provides a glimpse at the pursuit-and future-of personalized medicine.
The badgers of Wytham Woods (Oxford, UK) have been studied continuously and intensively by David Macdonald for almost 50 years (25 of them with his former student and co-author Chris Newman), generating a wealth of data pertaining to every facet of their ecology and evolution. Through a mix ofaccessible, highly readable prose and cutting-edge science, the authors weave a riveting scientific story of the lives of these intriguing creatures, highlighting the insights offered to science more broadly through badgers as a model system. They provide a paradigm - from population down tomolecule - for a deeper understanding of mammalian behaviour, ecology, epidemiology, evolutionary biology, and conservation. The real value of this long-term study is particularly apparent with current and globally relevant challenges such as climate change, disease epidemics, and senescence. Thisunique dataset enables us to examine these issues in a context that only a half-century experiment can reveal.The Badgers of Wytham Woods will appeal to a broad audience of professional academics (especially carnivore and mammalian biologists), researchers and students at all levels, governmental and non-governmental wildlife bodies, and to the natural historian fascinated by wild animals and the remarkableprocesses of nature they exemplify.
Bovine tuberculosis is seriously damaging the UK dairy and beef industry. Many farmers believe culling badgers must be part of the solution, but in 2013 a record 300,000 people signed a Downing Street petition asking the government to stop planned culls of badgers in Somerset and Gloucestershire, fuelling media controversy and signalling the beginning of a social conflict that was acted out in studios, streets, fields and village halls across England. The four-year trial culls, which began that year, aimed to establish that culling was a viable way of tackling the disease, but the widely divergent experiences and values of policy-makers, farming, conservation and animal welfare supporters means that decades of science on the disease in badgers and the effects of culling has not helped resolve the dispute. Reporting on original, UK research council-funded social science, this book takes on the challenge of understanding the contrasting views involved. Listening carefully to what the different protagonists have to say, the book unpicks the way science is interpreted to sustain differing conclusions, and considers how social science thinking could contribute. The book develops a critical perspective on the increasingly important literature influenced by new materialism, the social science response to the Science Wars, and explores the extent to which a social movement around opposition to the culls is emerging. In approachable prose, this access-all-areas account describes the struggle to develop understanding through the messy process of research and the difficulties of scientific analysis and philosophical thought. As such, it provides a valuable resource for both research practitioners and teachers within the social sciences, as well as an accessible way for biological scientists, conservationists and farmers to reflect on the issues around the management of disease in livestock and wildlife.