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**A New York Times top 100 Notable Book of the Year** Alexander Bruno is a man with expensive problems. Sporting a tuxedo and trotting the globe, he has spent his adult life as a professional gambler. His particular line of work: backgammon, at which he extracts large sums of money from men who think they can challenge his peerless acumen. In Singapore, his luck turned. Maybe it had something to do with the Blot – a black spot which has emerged to distort Bruno’s vision. It’s not showing any signs of going away. As Bruno extends his losing streak in Berlin, it becomes clinically clear that the Blot is the symptom of something terrible. There’s a surgeon who can help, but surgery is going to involve a lot of money, and worse: returning home to the garish, hash-smoke streets of Berkeley, California. Here, the unseemly Keith Stolarsky – a childhood friend in possession of an empire of themed burger bars and thrift stores – is king. And he’s willing to help Bruno out. But there was always going to be a price.
Disney's infamous inky bad guy was the first Mouseverse villain to get his own comic book; by popular demand, the whole Silver Age series is collected in one volume!
Zoom meets Beautiful Oops! in this memorable picture book debut about the creative process, and the way in which "mistakes" can blossom into inspiration One eye was bigger than the other. That was a mistake. The weird frog-cat-cow thing? It made an excellent bush. And the inky smudges… they look as if they were always meant to be leaves floating gently across the sky. As one artist incorporates accidental splotches, spots, and misshapen things into her art, she transforms her piece in quirky and unexpected ways, taking readers on a journey through her process. Told in minimal, playful text, this story shows readers that even the biggest “mistakes” can be the source of the brightest ideas—and that, at the end of the day, we are all works in progress, too. Fans of Peter Reynolds’s Ish and Patrick McDonnell’s A Perfectly Messed-Up Story will love the funny, poignant, completely unique storytelling of The Book of Mistakes. And, like Oh, The Places You’ll Go!, it makes the perfect graduation gift, encouraging readers to have a positive outlook as they learn to face life’s obstacles.
In The Protein Protocols Handbook, I have attempted to provide a cross-section of analytical techniques commonly used for proteins and peptides, thus providing a benehtop manual and guide both for those who are new to the protein chemistry laboratory and for those more established workers who wish to use a technique for the first time. We each, of course, have our own favorite, commonly used gel system, g- staining method, blotting method, and so on; I'm sure you will find yours here. H- ever, I have also described a variety of altematives for many of these techniques; though they may not be superior to the methods you commonly use, they may nev- theless be more appropriate in a particular situation. Only by knowing the range of techniques that are available to you, and the strengths and limitations of these te- niques, will you be able to choose the method that best suits your purpose.
A thrilling new voice in fiction injects the absurd into the everyday to present a startling vision of modern life, “[as] if Kafka and Camus and Bradbury were penning episodes of Black Mirror” (Chang-Rae Lee, author of My Year Abroad). “Stories so sharp and ingenious you may cut yourself on them while reading.”—Kelly Link, author of Get In Trouble With a focus on the weird and eerie forces that lurk beneath the surface of ordinary experience, Kate Folk’s debut collection is perfectly pitched to the madness of our current moment. A medical ward for a mysterious bone-melting disorder is the setting of a perilous love triangle. A curtain of void obliterates the globe at a steady pace, forcing Earth’s remaining inhabitants to decide with whom they want to spend eternity. A man fleeing personal scandal enters a codependent relationship with a house that requires a particularly demanding level of care. And in the title story, originally published in The New Yorker, a woman in San Francisco uses dating apps to find a partner despite the threat posed by “blots,” preternaturally handsome artificial men dispatched by Russian hackers to steal data. Meanwhile, in a poignant companion piece, a woman and a blot forge a genuine, albeit doomed, connection. Prescient and wildly imaginative, Out There depicts an uncanny landscape that holds a mirror to our subconscious fears and desires. Each story beats with its own fierce heart, and together they herald an exciting new arrival in the tradition of speculative literary fiction.
Uniquely integrates the theory and practice of key experimental techniques for bioscience undergraduates. Now includes drug discovery and clinical biochemistry.
The second edition of this book constitutes a comprehensive manual of new techniques for setting up mammalian cell lines for production of biopharmaceuticals, and for optimizing critical parameters for cell culture considering the whole cascade from lab to final production. The chapters are written by world-renowned experts and the volume’s five parts reflect the processes required for different stages of production. This book is a compendium of techniques for scientists in both industrial and research laboratories that use mammalian cells for biotechnology purposes.
Step-by-step instructions that ensure successful results.
Classical histology has been augmented by immunohistochemistry (the use of specific antibodies to stain particular molecular species in situ). Immunohistochemistry has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method.* The only book available that translates molecular genetics into cancer diagnosis * Methods were developed by internationally-recognized experts and presented in step-by-step manner * Results of each Immunohistochemical and in situ hybridization are presented in the form of color illustrations
"The one, only, and by far the best book synthesizing psychology and investing. In addition to providing modern, scientific knowledge about psychology, this book provides a mirror into the mind and wide breadth of knowledge of one of the leading practitioners of brief and effectual cures. Will help to cure your trading and your life." -Victor Niederhoffer, Chief Speculator, Manchester Investments Author, The Education of a Speculator and Practical Speculation "How refreshing! A book that rises above the old NLP model of the 80's and provides insights on how our relationship with the market is indeed a very personal one. Not only has Steenbarger provided some fantastic tools for the trader to transform his mindset, but he has contributed unique trading ideas as well. Brilliant!" -Linda Raschke, President, LBRGroup, Inc. "'Investigate, before you invest' was for many years the slogan of the New York Stock Exchange. I always thought a better one would be, 'Investigate YOURSELF, before you invest.' The Psychology of Trading should help you increase your annual investment rate of return. Mandatory reading for anyone intending to earn a livelihood through trading. " -Yale Hirsch, The Hirsch Organization Inc., Editor, The Stock Trader's Almanac "This highly readable, highly educational, and highly entertaining book will teach you as much about yourself as about trading. It's Oliver Sacks meets Mr. Market-extraordinary tales of ordinary professionals and individuals with investment disorders, and how they successfully overcame them. It is a must-read both for private investors who have been shell-shocked in the bear market and want to learn how to start again, as well as for pros who seek an extra edge from extra inner knowledge. Steenbarger's personal voyage into the mind of the market is destined to become a classic." -Jon Markman, Managing Editor, CNBC on MSN Money Author, Online Investing and Swing Trading "Dr. Steenbarger's fascinating, highly readable blend of practical insights from his dual careers as a brilliant psychologist and trader will benefit every investor; knowing oneself is as important as knowing the market." -Laurel Kenner, CNBC.com Columnist, Author, Practical Speculation