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Approx.317 pages
"Endless forms most beautiful and most wonderful have been, and are being, evolved," Darwin famously concluded The Origin of Species, and for confirmation we look to...the guinea pig? How this curious creature and others as humble (and as fast-breeding) have helped unlock the mystery of inheritance is the unlikely story Jim Endersby tells in this book. Biology today promises everything from better foods or cures for common diseases to the alarming prospect of redesigning life itself. Looking at the organisms that have made all this possible gives us a new way of understanding how we got here--and perhaps of thinking about where we're going. Instead of a history of which great scientists had which great ideas, this story of passionflowers and hawkweeds, of zebra fish and viruses, offers a bird's (or rodent's) eye view of the work that makes science possible. Mixing the celebrities of genetics, like the fruit fly, with forgotten players such as the evening primrose, the book follows the unfolding history of biological inheritance from Aristotle's search for the "universal, absolute truth of fishiness" to the apparently absurd speculations of eighteenth-century natural philosophers to the spectacular findings of our day--which may prove to be the absurdities of tomorrow. The result is a quirky, enlightening, and thoroughly engaging perspective on the history of heredity and genetics, tracing the slow, uncertain path--complete with entertaining diversions and dead ends--that led us from the ancient world's understanding of inheritance to modern genetics.
Stories of ten men and women, from the 1770s to the present, who devoted their lives, and sometimes risked them, to answer some of the big questions in science and medicine.
This is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well illustrated reference includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model. It is a resource for advancements in the humane and responsible care of: rabbit, guinea pig, hamster, gerbil, chinchilla, deer mouse, kangaroo rat, cotton rat, sand rat, and degu Includes up-to-date, common experimental methods. Organized by species for easy access during bench research.
This book provides a comprehensive text covering all aspects of guinea pig medicine. This updated edition will be of value to veterinary surgeons and students, veterinary nurses, breeders and all those working in the animal care industry. Written in note form the book assists in the formulation of a diagnostic plan when the practitioner is faced with a sick animal. Sections on clinical signs, diagnoses and treatments, allow rapid reference in successive chapters on the reproductive, digestive, respiratory, musculoskeletal and urinary systems, the skin, head and neck, nervous system and husbandry. All the latest drug information has been included and full details of dose rates, contraindications and components of the proprietary preparations are listed in chapter 11. A new chapter has been written providing information on herbal and homeopathic remedies.
Laboratory animals play an important role in biomedical research and advances. Expanded, updated, and now published in full color to provide greater clarity to the techniques and concepts discussed, this guide presents basic information and common procedures in detail to provide a quick reference for investigators, technicians, and caretakers in the laboratory setting. It includes additional information on the research uses of the guinea pig along with updated medical care information.
The guinea pig is so widely used in laboratories that it has become synonymous in common speech with "experimental animal." But until now there has been no complete and accurate anatomy of this otherwise familiar creature. Cavia has remained uncharted territory for experimenters who come to it without previous experience. Gale Cooper and Alan L. Schiller here provide a thorough description of guinea pig anatomy in a text illustrated with about four hundred separate drawings. It is a detailed, complete, and practical guide to the gross morphology of the animal. Nomenclature has been standardized according to the Nomina Anatomica Veterinaria. The authors' dissections have been carefully correlated with the published literature on guinea pig anatomy, and numerous references are given. This book sets a new standard of beauty and clarity in anatomical illustration. Dr. Cooper's drawings not only provide anatomical information with the utmost in accuracy and fidelity, they are in themselves an aesthetic triumph. Her pencil drawings have been made by a technique that requires specially made paper and demands unusual skill from the artist; closely identified with the famous illustrator Max Brodl, this method is now rarely employed. Researchers in immunology, hematology, physiology, biochemistry, pharmacology, reproductive biology, comparative anatomy, and taxonomy, among other fields, will turn to this anatomy as a reliable guide to a favored experimental species.
In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.
Exotic Animal Emergency and Critical Care Medicine delivers the most relevant and current information required by general veterinary practitioners and veterinary specialists in treating emergent and critical exotic patients. Covering the management of common emergency presentations in exotic companion mammals, birds, reptiles, and amphibians, each section discusses triage and stabilization, diagnostics, nutrition and fluid therapy, analgesia, anesthesia, monitoring, CPR, and euthanasia. The book includes quick reference tables, species-specific drug formularies, and illustrations of exotic animal emergency procedures and techniques. The information contained within is based on an extensive review of the most current literature and the combined knowledge and expertise of international leaders in the field of exotic animal medicine and surgery. A one-stop resource like no other, Exotic Animal Emergency and Critical Care Medicine makes it easy to find the information needed to effectively treat urgent and life-threatening conditions in pet exotic animals. The book covers a wide range of species, encompassing: Exotic companion mammals, including ferrets, rabbits, guinea pigs, chinchillas, rats, mice, hamsters, gerbils, hedgehogs, and sugar gliders Birds, including psittacines, passerines, doves and pigeons, as well as backyard poultry and waterfowl Reptiles, including turtles and tortoises, snakes and lizards Amphibians Equally useful for general practitioners, specialists in emergency and critical care and exotic animal medicine, veterinary students, and trainees, Exotic Animal Emergency and Critical Care Medicine is an essential resource for the emergent and critical care of exotic animals.
The Professional Guinea Pig documents the emergence of the professional research subject in Phase I clinical trials testing the safety of drugs in development. Until the mid-1970s Phase I trials were conducted on prisoners. After that practice was outlawed, the pharmaceutical industry needed a replacement population and began to aggressively recruit healthy, paid subjects, some of whom came to depend on the income, earning their living by continuously taking part in these trials. Drawing on ethnographic research among self-identified “professional guinea pigs” in Philadelphia, Roberto Abadie examines their experiences and views on the conduct of the trials and the risks they assume by participating. Some of the research subjects he met had taken part in more than eighty Phase I trials. While the professional guinea pigs tended to believe that most clinical trials pose only a moderate health risk, Abadie contends that the hazards presented by continuous participation, such as exposure to potentially dangerous drug interactions, are discounted or ignored by research subjects in need of money. The risks to professional guinea pigs are also disregarded by the pharmaceutical industry, which has become dependent on the routine participation of experienced research subjects. Arguing that financial incentives compromise the ethical imperative for informed consent to be freely given by clinical-trials subjects, Abadie confirms the need to reform policies regulating the participation of paid subjects in Phase I clinical trials.