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This book explores the underlying biology associated with the pathology of mental health disorders and the related nervous system. Fully revised for this third edition, each chapter has been updated to include the latest research, ideas and concepts in each field, and includes a new chapter on sleep. Integrating up-to-date pharmacological and genetic knowledge with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health covers topics including brain development, neural communication, neurotransmitters and receptors, hormones and behaviour, genetic disorders, pharmacology, drug abuse, anxiety, schizophrenia, depression, epilepsy, subcortical degenerative diseases of the brain, dementia, developmental disorders, and sleep. Accessible and engaging, this is an essential text for mental health students, practitioners and educators.
It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
This book is an introduction to the biological basis of behavior, broadly defined, with practical applications for higher education programs that focus on advances in neuroscience. It has a special focus on training practitioners based on American Psychological Association (APA) health service psychology guidelines. It reviews and digests information for clinical, counseling, and school psychologists serving clients of all ages in a variety of settings, such as schools, hospitals, and clinics. Content for all developmental stages, including birth to geriatric practices are highlighted. Some unique features of this book include: The integration of neuropsychological and theoretical foundations for clinical practice. Comprehensive consideration of projective, objective, and interviewing measures. Recent research in neuroimaging as it relates to clinical practice. Psychopharmacology and its effect within the neurosciences. Assessment for intervention in clinical, counseling, school, and neuropsychology. The use of research to guide neuropsychologically-based clinical practice. Eastern and western approaches to integration and case conceptualization. Interventions driven by brain-based scientific understanding. A variety of neuropsychological cases and report styles to improve practice The enduring contribution of psychology into modern times will remain contingent on practitioners' commitment to ethically-based, empirically-focused, evidence-based practice; continuing education; and scientific discovery. This book will help health service psychologists and counselors to meet the needs of an increasingly diverse population by providing cutting-edge, evidence-based, ecologically valid neuropsychological interventions currently lacking within the field. Cultural considerations are provided within each chapter, which is especially important given societal inequity that continues to persist within our world. Implications for the COVID-19 pandemic are also discussed in light of neuroscientific advances in medicine.
This classic is one of the most cited and novel approaches to psychology ever written. Hans Eysenck presents a descriptive and causal model of human personality in accord with the major concepts of experimental psychology and the physiological and neurological mechanisms that form the biological basis of behavior patterns. His proposal for an alliance between personality and physiology represented a major innovation in the field of psychology, distinguished his research from his contemporaries, and set the stage for a wealth of research to come. Before this foundational work, Eysenck had initially constructed a model of personality in such works as Dimensions of Personality and The Experimental Study of Personality, but these were primarily descriptive in nature. A second phase of research included his Dynamics of Anxiety and Hysteria and Experiments with Drugs, where he provided causal analysis by reference to concepts then current in experimental psychology. The Biological Basis of Personality represents Eysenck's third phase, when he dug deeper to find biological causes underlying the psychological concepts of emotion, excitation, and inhibition--which had formed the building blocks of his earlier efforts. In this work, the causal links he postulates between personality variables and neurological and physiological discoveries establish a realistic model that takes theory out of the field of mere speculation. As Sybil Eysenck makes clear in her new preface, this book paved the way for a "marriage" of the experimental and individual difference approach in personality psychology. As Sybil Eysenck makes clear in her new preface, this book paved the way for a "marriage" of the experimental and individual difference approach in personality psychology.
It is now widely recognised that biological psychiatry is rapidly coming into its own. For over the last three decades dramatic advances in this young discipline have been made, all of which attest to the staying power of the experimental method. Those who made this revolution in knowledge happen are a breed of investigators availing themselves of the tools of molecular biology, pharmacology, genetics, and perhaps, above all, the technology of neuroimaging. The introduction of the interdisciplinary method of approach to the study of psychopathology had made it very clear that neuroimaging, as a set of techniques, is unique in that it is gradually providing us with evidence supporting Kraepelin's original view that mental illness is closely associated with abnormal changes in the brain.Broadly speaking, there are presently two structural techniques in neuroimaging - computed tomography and magnetic resonance imaging (MRI) - and three functional techniques - single photon emission tomography (SPECT), positron emission tomography and magnetic resonance imaging (fMRI). Through PET technology, for example, we have learned that, in early brain development, the primitive areas, mostly the brain stem and thalamus, are the first to show high activity in an infant. This is followed by the development of cortical areas by year one. Between the ages of four to 10, the cortex is almost twice as active in the child as in the adult. This information alerts us to what might happen in the way of trauma in abused children, especially those under the age of three. Child abuse increases the risk of physical changes, not only in the stress systems, but also in brain development (Glaser and Weissman). In addition to the difficult problem of post-traumatic stress disorder (PTSD), we have to take into account the possibility of other types of mental illness as the consequences of child abuse. These include depression, eating disorders, and drug and alcohol problems.The combination of PET and fMRI represents a more remarkable example of the power of neuroimaging since the two have made it feasible to map accurately in vitro identifiable cortical fields, or networks. In a landmark NIH investigation of human cortical reorganization (plasticity), persuasive evidence was brought forward showing that the process of learning as a motor task involves a specific network of neurons. These neurons occur in the cortical field that is responsible for that particular task. Such findings are important partly because they provide evidence supporting the current notion that labor in the cortex is divided among ensembles of specialized neurons that cooperate in the performance of complex tasks. Cooperation, then, in this, sense implies crosstalk among ensembles and that signals are both processed and retransmitted to neighbouring ensembles. To understand the workings of these ensembles, much better spatial and temporal resolution in functional brain mapping is required. This can be achieved with an NMR instrument whose magnet is 4.1 Tesla or more.
This is a revised and updated edition of a text used in undergraduate courses on cancer biology. It covers everything from the molecular basis of cancer to clinical aspects of the subject, and has a lengthy bibliography designed to assist newcomers with the cancer literature. An introduction acquaints students with the biological principles of cancer and the human dimensions of the disease by considering genuine cases of cancer in fictionalized letters. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer, a glossary of cancer-related terms and colour plates to illustrate the pathology of many of the types of cancer discussed in the text. Upper-division undergraduates with a background in freshman biology and chemistry, as well as beginning graduate students will find this a valuable text.
Accurate clinical observations are key to good patient care and fundamental to clinical practice. A thorough understanding of the biological science underlying vital observations – such as taking the temperature or measuring the pulse – enables health professionals to make well-informed clinical decisions quickly and accurately. To be fully competent in these basic skills, there is a need to understand not only how and why procedures are performed, but also how results are affected, for example by variation in technique or the health status of the patient. This new edition integrates clear explanations of the techniques involved in these procedures with the biological knowledge which gives them meaning. For each topic, William T. Blows explains the pathological basis for variations in observed results, focusing on relevant anatomy and physiology, genetics and pharmacology and the basic principles of care. This helpful text gives health practitioners at all levels the understanding needed to: Perform clinical observations accurately Make accurate judgements about the patient’s condition Make accurate decisions concerning patient care. In addition to all-new chapters on observations of nutrition; fluid balance and hydration; drug side effects and interactions; skin and pain, the text looks at: Temperature Cardiovascular observations Respiratory observations Urinary and bowel observations Neurological observations The Biological Basis of Clinical Observations is a unique text which integrates explanations of essential procedures with the biological knowledge that underpins practice. It is essential reading for all students preparing for clinical practice.
Providing easy-to-access information, this unique sourcebook covers the wide range of topics that a researcher must be familiar with in order to become a successful experimental scientist. Perfect for aspiring as well as practicing professionals in the medical and biological sciences it discusses a broad range of topics that are common, yet not traditionally considered part of formal curricula. The information presented also facilitates communication across conventional disciplinary boundaries, in line with the increasingly multidisciplinary nature of modern research projects. - Perfect for students with various professional backgrounds providing a broad scientific perspective - Easily accessible, concise material makes learning about diverse methods achievable in today's fast-paced world
Revised and updated to meet the needs of students, academics and AIDS professionals, this book has critical, up-t-date information on AIDS and HIV, including: the physiology of the HIV-T-cell relationship; the spread of AIDS throughout Africa and Asia; new insights into needle exchange programs; how the viral load has become a key diagnostic tool for tracking HIV infection; the use of zidovudine to control pediatric AIDS; work on the AIDS vaccine; and the use of HAART to control AIDS in adults.