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Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. - Provides high-resolution images for best visualization of key developmental processes and structures - Offers in-depth anatomy and morphological views of organ systems - Written descriptions convey developmental origins of the organ systems
Not since the early 1970s has there been an attempt to describe and illustrate the anatomy of the developing mouse embryo. More than ever such material is needed by biologists as they begin to unravel the molecular mechanisms underlying development and differentiation. After more than ten years of painstaking work, Matt Kaufman has completed The Atlas of Mouse Development--the definitive account of mouse embryology and development. For all those researching or studying mammalian development, The Atlas of Mouse Development will be the standard reference work for many years to come. Provides a comprehensive sequential account of the development of the mouse from pre-implantation to term Contains clear and concise descriptions of the anatomical features relevant to each stage of development Large format for easy use Contains explanatory notes and legends, and more than 180 meticulously labeled plates, 1,300 photographs of individual histological sections, and 200 electron micrographs, illustrating: Intermittent serial histological sections through embryos throughout embryogenesis and organogenesis Differentiation of specific organs and organ systems, including the spinal cord, eyes, gonads, kidneys, lungs and skeletal system External appearance of intact embryos throughout development
This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference. *Broad-based overview of mouse development from fundamental to specialist levels *Extensive coverage of a wide range of developmental mutations of the mouse *Excellent benchmark illustrations of brain, craniofacial, gut and heart development *In-depth experiment-based assessment of concepts in mammalian development *Focus on models of specific relevance to human development *Comprehensive reference to key literature and electronic databases related to mouse development *High-quality full-color production
Atlas of the Developing Mouse Brain, Second Edition builds on the features of successful first edition, providing a comprehensive and convenient reference for all areas of the mouse brain at Fetal-Day 17.5 (E17.5), Day-of-Birth (P0), and Day-Six postnatal (P6). The book also delineates the parts of the eye, features of the skull, ganglia, nerves, arteries, veins, bones and foramina. This atlas is an essential tool for researchers and students who study the development of the mouse brain, or for those who interpret findings from genetic manipulation. - Contains 176 high-resolution color scans of Nissl-stained coronal sections of the brain and skull of the fetal (E17.5), day-of-birth (P0), and day-six postnatal mouse (P6) - Includes diagrams that delineate all structures of the brain, as well as peripheral nerves, ganglia, muscles, bones, veins and arteries of the head - Presents approximately 5000 corrections and updates from the first edition - Includes color codes of the veins, arteries, nerves and ganglions of the skull in diagrams
This is the only book available for studies of the mouse brain before birth. It presents a complete mapping of the developing mouse brain that features imaging of whole brain sections. Users will be able to compare structure shown in the Atlas to what they see in the microscope. This new, greatly expanded edition provides an easily accessible tool for researchers in the fields of normal and abnormal brain development.
Representing the state-of-the-art in neurochemical mapping, Chemoarchitectonic Atlas of the Developing Mouse Brain provides a complete, full-color look at the developing mouse brain. Hundreds of coronal sections are presented, clearly illustrating structures at progressive stages of brain development.
This book is an essential anatomical resource for developmental biologists who need to know about any aspect of mouse developmental anatomy, as well as for geneticists using the mouse embryo as a model. The book is a companion to Kaufman's The Atlas of Mouse Development, and details the developmental anatomy of the early embryo, the transitional tissues, and all the major organ systems. It also provides extensive comparisons with human developmental anatomy, both normal and abnormal. The book has extensive reference indexes detailing developmental stage criteria. The Anatomical Basis of Mouse Development will be a key reference work for anyone who needs to understand developmental anatomy in normal and mutant mice. - Complements Kaufman's The Atlas of Mouse Development - Gives anatomical descriptions from oogenesis to birth, at a level of detail that goes beyond that found in most literature - Provides detailed explanations for geneticists and molecular biologists with limited anatomical background to help them understand the emergence of all the major structures in the mouse embryo - Contains comprehensive indexes detailing the appearance of over 1000 organs, tissues, and their components at different stages of mouse embryogenesis - Includes comparisons with normal and abnormal human development - Contains over 100 clear line diagrams showing mouse developmental anatomy as well as lineage relationships for the major organ systems
Morphological Mouse Phenotyping: Anatomy, Histology and Imaging is an atlas of explanatory diagrams and text that guides the reader through normal mouse anatomy, histology, and imaging. The book is targeted for mouse researchers and veterinarian and human pathologists, and presents a complete, integrative description of normal mouse morphology. Disease animal models are fundamental in research to improve human health. The success of using genetically engineered mice to evaluate molecular disease hypotheses has encouraged the development of massive global projects, making the mouse the most used animal disease model. Laboratory mouse populations are straining the housing capacity of pharmaceutical and biotechnology companies, as well as public research institutions. However, the scientific community lacks sufficient expertise in morphological phenotyping to effectively characterize and validate these animal models. The mouse displays fundamental morphological similarities to humans; however, a mouse is not a man. - Features more than 2,200 original images showing the anatomy, histology, and cellular structure of mouse organs - Includes images specifically produced for this book in the Mouse Imaging Platform (Center for Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona) - Offers an integrative vision of mouse morphology using correlative X-ray, computed tomography, magnetic resonance, and ultrasound images - Employs classical anatomical techniques such as conventional dissection, skeletal preparations, vascular injections, and histological, immunohistochemical, and electron microscopy techniques to characterize mouse morphology
The Anatomical Basis of Mouse Development by Kaufman and Bard is an essential anatomical resource for developmental biologists needing to know about any aspect of mouse developmental anatomy, as well as for geneticists using the mouse embryo as a model. This book is a companion to Kaufman's The Atlas of Mouse Development and details the developmental anatomy of the early embryo, the transitional tissues, and all the major organ systems. It also includes extensive reference indexes detailing developmental stage criteria, when tissues first appear, and the constituent tissues of embryos at each of the 26 Theiler stages, as well as tissue and author indexes and a glossary. Key features: * Gives anatomical descriptions from oogenesis to birth at a level of detail that often goes beyond that found in the literature. * Provides detailed explanations for geneticists and molecular biologists with limited anatomical background to help them understand the emergence of all the major structures in the mouse embryo. * Contains comprehensive indexes detailing the appearance of over 1000 organs, tissues and their components at different stages of mouse embryogenesis, together with the Theiler developmental stages (1-26) at which each first appears. * Includes comparisons with normal and abnormal human development * Has over 100 clear line diagrams showing mouse developmental anatomy as well as lineage relationships for the major organ systems. This book will be a key reference work for anyone who needs to understand developmental anatomy in normal and mutant mice.
Guide to Techniques in Mouse Development, Part A comprehensively covers new technologies and methodologies that have appeared for the study of mouse development. - Update of volume 225 of Methods in Enzymology, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993 - Covers new technologies and methodologies, including: - new techniques for the cryopreservation of gametes and embryos - production of transgenic and null (knockout) animals (use of ES cells) - generation of conditional/inducible mutant animals - use of gene-trap mutagenesis - analysis of allele-specific expresion - use of new reporter constructs - humanizing of transgenic animals - transcript profiling of mouse development - imaging of mouse development - rederivation of animals and use of mouse genomics