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Many vital medical techniques are based on fundamental bioelectric and biomagnetic phenomena-electrocardiographs and cardiac pacemakers are two examples. This book examines the fundamental science underlying these techniques.
This text applies engineering science and technology to biological cells and tissues that are electrically conducting and excitable. It describes the theory and a wide range of applications in both electric and magnetic fields.
Biomagnetism is the study of magnetic fields that originate in biological systems. This is a relatively new discipline that has attracted considerable interest throughout the scientific commu- ty. The study of biomagnetic fields requires the use of techniques and concepts drawn from widely disparate scientific disciplines. To make these techniques and concepts available to a wide spectrum of the scientific community, a NATO Advanced study Institute on B- magnetism was held near Frascati at Grottaferrata, Italy, in S- tember 1982. This volume is based on the lectures delivered by scholars representing many different scientific areas, ranging from solid state physics to psychology. It attempts to preserve the - herent development of concepts drawn from physiology, psychology, biology, physics, medicine, occupational health and geology that was evident during the Institute. The reader will quickly become aware that the progress in biomagnetism over the past decade was due principally to the efforts of interdisciplinary teams of sci- tists. One of the purposes of this volume is to make all of the basic principles and findings of biomagnetism available in one place, so that scientists who have already embarked on the study of biomagnetism or who plan to do so in the near future will have them available for study and reference. Each section of this volume was written by a recognized expert who lectured at the Institute on the topics he describes here.
Biomagnetism involves the investigation of bioelectric processes as reflected by their accompanying magnetic fields. These processes can be monitored in the brain, heart, peripheral nerve or gastrointestinal tract. SQUID technology can also be used for biosusceptometry in lung, liver and intestines. Biomagnetism also includes theoretical issues as encountered in the inverse problem, modelling, fundamentals, physics and mathematics of the method, technical applications and instrumentation, as well as future aspects.
Topics include studies of the brain, heart, liver, lungs, muscle, tissue in vitro, advances in instrumentation, development of theory, and related subjects. Three major advances are revealed: newly developed large arrays of magnetic sensors which can sample simultaneously a field pattern from many
Designed for biology, physics, and medical students, Introductory Biophysics: Perspectives on the Living State, provides a comprehensive overview of the complex subject of biological physics. The companion CD-ROM, with MATLAB examples and the student version of QuickFieldTM, allows the student to perform biophysical simulations and modify the textbook example files. Included in the text are computer simulations of thermodynamics, astrobiology, the response of living cells to external fields, chaos in population dynamics, numerical models of evolution, electrical circuit models of cell suspension, gap junctions, and neuronal action potentials. With this text students will be able to perform biophysical simulations within hours. MATLAB examples include; the Hodgkin Huxley equations; the FitzHugh-Nagumo model of action potentials; fractal structures in biology; chaos in population dynamics; the cellular automaton model (the game of life); pattern formation in reaction-diffusion systems. QuickFieldTM tutorials and examples include; calculation of currents in biological tissue; cells under electrical stimulation; induced membrane potentials; heat transfer and analysis of stress in biomaterials.
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