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Boxing Day circa 1935. A snowed-in manor on the very edge of Dartmoor. A Christmas house-party. And overhead, in the attic, the dead body of Raymond Gentry, gossip columnist and blackmailer, shot through the heart. But the attic door is locked from the inside, its sole window is traversed by thick iron bars and, naturally, there is no sign of a murderer or a murder weapon. Fortunately (though, for the murderer, unfortunately), one of the guests is the formidable Evadne Mount, the bestselling author of countless classic whodunits. In fact, were she not its presiding sleuth, THE ACT OF ROGER MURGATROYD is exactly the type of whodunit she herself might have written.
The writer and professional controversialist Gustav Slavorigin is murdered in the small Swiss town of Meiringen during its annual Sherlock Holmes Festival, his body discovered with an arrow through the heart. With a price of ten million dollars on Slavorigin's head, almost none of the Festival's guests can be regarded as above suspicion. Except Evadne Mount, of course, the stubborn amateur sleuth and bestselling crime novelist from Gilbert Adair's The Act of Roger Murgatroyd and A Mysterious Affair of Style. Neither of those two cases, however, prepared her for the jaw-dropping twists of this new investigation, which climaxes at Meiringen's principal tourist attraction, the Reichenbach Falls - the site of Holmes's fatal confrontation with his nemesis, Moriarty . . .
Two men, driving from opposite directions along a lonely road in France, find themselves forced to exchange cars when a tree renders the road impassable. From that moment on, a spate of Hitchcockian events unfold.
Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. - Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry - Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system - Explores translational potential of targeting immune dysfunction for clinical interventions
The central character of Alan Ayckbourn's new play is Susan, a parson's wife, 'one of the most moving and devastating that he has created...' Robin Thornber reviewing the first production in Scarborough in the Guardian.
Written by celebrated author M. M. Kaye, Death in Kasmir is a wonderfully evocative mystery ... When young Sarah Parrish takes a skiing vacation to Gulmarg, a resort nestled in the mountains above the fabled Vale of Kashmir, she anticipates an entertaining but uneventful stay. But when she discovers that the deaths of two in her party are the result of foul play, she finds herself entrusted with a mission of unforeseen importance. And when she leaves the ski slopes for the Waterwitch, a private houseboat on the placid shores of the Dal Lake near Srinagar, she discovers to her horror that the killer will stop at nothing to prevent Sarah from piecing the puzzle together.
A reserved British intellectual falls obsessively in love with a young American heartthrob, in this witty and poignant “tour de force” (Literary Review). When he wanders into the wrong theater and finds himself watching the wretched teen-pic Hotpants College II, cerebral British author Giles De’Ath becomes romantically obsessed with dreamboat Ronnie Bostock. Giles’s infatuation drives him to the unthinkable: he reads American fan magazines and watches movies with titles like Tex Mex and Skid Marks. And finally, he travels to Long Island, intent on meeting Ronnie in the flesh. The basis for the hit independent film starring Jason Priestley and John Hurt, Love and Death on Long Island is a brilliant and heartrending update of Thomas Mann’s early twentieth-century novella Death in Venice. It offers both a poignant meditation on passion, and “a very funny portrait of an extraordinarily unworldly academic’s introduction to the dizzyingly incomprehensible realm of popular culture” (Nick Hornby). “Brief, pure, intense . . . The writing is masterly, the conjuring of contrasting worlds a triumph.” —The Financial Times