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The rapidly growing field of immunopsychiatry combines expertise and insights from immunology, psychiatry and neuroscience to understand the role of inflammation and other immune processes in causing and treating mental illness. This represents a major shift in mental health science, traditionally focused on psychological and neuronal mechanisms of depression, psychosis and dementia. This book provides the first comprehensive overview of recent, inter-disciplinary research linking disordered function of the immune system to the brain and mental illness. It offers a broad and deep perspective on the implications of immune system involvement in psychiatric disorders, including a balanced focus on basic science and clinical applications. Chapters cover the scientific evidence linking immune processes to major mental illnesses such as schizophrenia, depression, anxiety and dementia. An invaluable guide for graduate students, doctors in training, scientific researchers and others interested in the link between the immune system and mental health.
An essential book summarizing cutting-edge evidence on the role of the immune system and immunotherapies in psychiatric disorders.
This book presents a thorough and critical review of current knowledge on the role of immunology in major psychiatric disorders and its potential applications. The opening chapters offer general information on the immune influence of the brain to provide readers with a better understanding of the end of immune privilege. The book then examines possible underlying mechanisms leading to psychiatric disorders, from early infections to pro-inflammatory markers, stress, and immune genetic background, linking etiology and psychiatry. The third section describes each disorder (ie autism, schizophrenia, bipolar disorder, depression...) with an overview of underlying immune dysfunctions. Lastly, the authors discuss the innovative immune-therapies that may result from the discovery of immune system biomarkers and their associated mechanisms. A better understanding of the role of the immune system in psychiatric disorders makes it possible to identify stratification biomarkers, to explain underlying mechanisms, and to develop innovative, efficient, targeted treatment strategies and management. As such, the book is of value to clinicians, mental health professionals, mental health researchers, immunologists, industry practitioners, and various stakeholders in the mental health field.
This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice.
A concise, practical guide to the mental health effects of COVID-19 and its treatments Managing Mental Illness After COVID-19 Infection is a resource for people affected by COVID-19 and their loved ones. As the long-term effects, especially the psychiatric effects, evolve and become more common, people are increasingly searching for answers. This book reviews presentations and treatments for mental illnesses post-COVID-19. Readers will learn about the use of medications, supplements, and behavioral interventions to address these conditions. This engaging and practical book includes numerous tables and other illustrations for easy reference. It provides enough medical detail for patients and their caregivers to better understand the symptoms they may experience, as well as the best ways to investigate and treat those symptoms. However, it is not too complex for the general reader, making it perfect as a standalone book for patients and their families. Learn how and why many people struggle with mental illness following COVID-19 infection Discover what your symptoms may indicate and get advice on how to pursue diagnosis and treatment Find a doctor who can understand and manage the mental and behavioral consequences of COVID-19 Get up to speed on the psychiatric and psychosocial effects of COVID-19 infection This is an excellent resource for the public, policymakers, clinicians, counselors, social workers, and behavioral health coaches that could benefit from the latest research on the psychiatric effects of COVID-19.
Many people consider stopping their psychiatric medications, but prescribers may not know how to do this in a collaborative, systematic way. This book describes the ins and outs of how clinicians can work closely with their patients to consider whether or not to try decreasing medications. It outlines the how and when, and gives recommendations on what the prescriber and patient may encounter along the way.
Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. - Winner of the 2017 PROSE Award in Biomedicine & Neuroscience and the 2017 British Medical Association (BMA) Award in Neurology - Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems - Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience - Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain
This book presents a complete summary about the 12 pairs of cranial nerves (CN). They control much of the motor and sensory functions of the head and neck such as smell, sight, eye movement, and feeling in the face. The CN also control balance, hearing, and swallowing. The examination of the CN is an important part of the clinical neurological examination. Additionally, to the anatomy, extensive knowledge about further diagnostic tools are necessary such as neuroimaging, and electrophysiology. The book is divided into three parts: a general part with anatomy and imaging, a systematic part grouping the 12 pairs of cranial nerves, and a part describing cranial nerve functions in specific conditions and diseases.
The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population that were not initially known to be linked to the inflammatory response, including cardiovascular disease, asthma, arthritis, and cancer. To better manage treatment, diagnosis, and prevention of these wide-ranging diseases, multidisciplinary research efforts are underway in both academic and industry settings. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion. World-class experts from institutions around the world have written chapters for this introductory text. The text is presented as an introductory springboard for graduate students, medical scientists, and researchers from other disciplines wishing to gain an appreciation and working knowledge of current cellular and molecular mechanisms fundamental to inflammation.
Health psychology is a rapidly expanding discipline at the interface of psychology and clinical medicine. This text offers a comprehensive, accessible, one-stop resource for clinical psychologists, mental health professionals and specialists in health-related matters.