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Taenia solium cysticercosis is a parasitic disease caused by the dissemination of the larval form of the pork tapeworm and affects an estimated 50 million people worldwide. It is endemic in several developing countries, including many in Central and South America, Africa and South Asia. Through increased immigration and international travel, it is also of emerging significance in developed countries such as the USA.This book, written by international leading experts in the field, covers the basic science and clinical aspects of Taenia solium, its pathology, investigational aspects of neurocysticercosis, and therapy and prevention
Cysticercosis, an infection caused by the cystic larvae of the pork tapeworm Taenia solium, is one of the most frequent parasitic infections of the human nervous system (neurocysticercosis). It is endemic in most of Latin America, the sub-Saharan Africa, and vast parts of Asia, including the Indian subcontinent. It has also been increasingly diagnosed in developed countries because of migration of people from endemic zones and exposure in travelers. The life cycle involves the development of the adult tapeworm in the human small intestine (after ingesting infected pork with cysts) and larval infection in pig tissues (after ingesting human stools containing the eggs of the tapeworm). Humans get infected by the fecal-oral route, most often from a direct contact with an asymptomatic Taenia carrier. Most common clinical presentations are seizures (particularly late-onset seizures), chronic headaches, and intracranial hypertension. However, cysticerci can locate anywhere in the human nervous system, thus potentially causing almost any neurological syndrome and making clinical diagnosis a difficult task. Neuroimaging is the main diagnostic tool, and specific serology confirms the diagnosis and helps to define the diagnosis when images are unclear. Factors such as location (extraparenchymal versus intraparenchymal), number, size and evolutive stage of the parasites determine the clinical manifestations, therapeutic approach, and prognosis. Management includes symptomatic drugs (analgesics, antiepileptic drugs, anti-inflammatory agents) and in many cases cysticidal drugs, either albendazole or praziquantel. In recent years, efforts have focused on transmission control and potential elimination in endemic regions.
The second volume in an annual series of books based on ICAAC Symposia, Emerging Infections 2 provides a complete and updated discussion of new and emerging infectious diseases, covering both basic science and clinical topics. Written by experts in the field, this new book offers broad coverage on topics ranging from prions and viruses to bacteria and helminths. It also includes chapters on food borne diseases in the 21st century, concerns in blood safety, and strategies for addressing emerging infections on a global scale. A foreword is written by U. S. Surgeon General Dr. David Satcher. This book and the series will be valuable to a wide range of people working in microbiology, infectious diseases, epidemiology, public health, and medicine.
Focusing solely on uveitis care, this quick reference guide will provide a compiled and easy to navigate differential diagnosis – making an often daunting task for clinicians easier, quicker, and more accurate by using a concise outline format to list the most critical aspects of a disease entity. Uveitis: A Quick Guide to Essential Diagnosis opens with a Diagnosis Flowchart, so that the reader can select the most probable diagnoses based on patient’s history and exam. From there the reader can then quickly turn to the corresponding chapter to learn about the most critical aspects of the disease entity: epidemiology, characteristic exam and imaging findings, prognostic factors, and treatment options. This book is written for ophthalmic care providers including general ophthalmologists, subspecialists, fellows, residents and optometrists and features research and contributions from institutions that are global leaders in uveitis care.
Neurocysticercosis is the most common parasitic disease of the nervous system worldwide. This is a comprehensive, single-source review of the history, epidemiology, biological and parasitological features of the disease, as well as its immunological, clinical, diagnostic and therapeutic aspects.
This book provides updated information to scientists and clinicians on taeniosis/cysticercosis, a parasitic infection caused by eating undercooked beef or pork that is a serious health and veterinary problem in many developing countries. It discusses incidence, risk factors, diagnosis, immunology, symptoms, rare manifestations, and advances in treatment including vaccination and novel drug therapies.
Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.
Widely used by students, residents, generalists, and specialists, Netter’s Infectious Diseases, 2nd Edition delivers must-know information on infectious diseases in a highly illustrated, easily accessible format. Concise visual overviews of essential topics provide a convenient, trustworthy way to review the basics of a given infectious disease or issue or to share with patients or staff. Drs. Elaine Jong and Dennis Stevens cover the wide spectrum of illness and disease in this complex field using memorable illustrations by world-renowned artist Frank H. Netter and others, offering a time-saving, authoritative look at infectious disease risk factors, clinical presentations, pathophysiology, and more. Covers major conditions and problems such as vaccine-preventable diseases, drug-resistant staph, community acquired pneumonia, surgical infections, pyelonephritis, viral hepatitis, and sexually transmitted infections—and provides updated approaches to diagnosis, treatment, prevention, and standards of care. Includes new clinical vignettes added to most chapters Provides updated and expanded coverage of emerging infectious diseases such as multidrug resistant tuberculosis (MDR-TB), neuroangiostrongyliasis (rat lungworm disease), Ebola virus, Severe Acute Respiratory Disease (SARS), Middle East Respiratory Syndrome (MERS), Coronavirus Infectious Disease-2019 (COVID-19), and novel influenza viruses including public health concerns. Covers vector-borne diseases including malaria, yellow fever, Zika infections and congenital Zika syndrome, West Nile fever, Lyme disease, tick-borne encephalitis, and Chagas disease plus others. New chapters on travelers’ diarrhea, cholera, and primary amebic meningoencephalitis debut in the section on international travel and outdoor activities. Contains memorable parasite life cycles and unforgettable parasite infection clinical vignettes. Features unparalleled illustrations by Drs. Frank H. Netter, Carlos Machado, and others, as well as radiologic images. Provides 24 printable patient education brochures in the digital ebook.
Intraocular inflammation is particularly difficult to diagnose and treat, often resembling a complex puzzle of patient history, symptoms, imaging, and laboratory test results. Clinical Cases in Uveitis: Differential Diagnosis and Management is a unique, case-based resource designed to help you navigate the range of challenging manifestations and presentations that often mimic other diseases. More than 90 real-world uveitis cases are presented in a highly templated, easy-to-follow format, along with step-by-step guidance on the right patient questions, assessment, differential diagnosis, testing, management, and follow-up care. Provides a variety of patient presentations and scenarios and unique clinical situations that mirror day-to-day practice. Covers current diagnostic imaging modalities, including optical coherence tomography (OCT), optical coherence tomography angiography, fluorescein angiography (FA), and indocyanine green angiography (ICG). Features diagnostic and management algorithms that assist in differential diagnosis and decision making for even the most complex cases, including those in which the patient does not improve as expected, prompting a reassessment of diagnosis and management. Contains approximately 250 high-quality images, including color anterior segment photographs, color fundus photographs, OCT images, and angiograms. Discusses distinguishing infectious from non-infectious inflammation; when and how to start systemic immunosuppressive therapy; diagnostic criteria and management of “white dot syndromes ; pediatric uveitis; masquerade syndromes, including inherited retinal degenerations, malignancies, and paraneoplastic syndromes; and much more. Includes the authors’ specific thought processes and approach in particularly challenging cases. An excellent resource and study tool for ophthalmology residents and fellows, those studying for oral boards, general ophthalmologists, retina specialists, and more.