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From a November 1999 symposium in Kansas City, Missouri, 12 papers explore aspects of biological implants that are absorbed by the body over time from the perspective of materials science. Their topics include the mechanical evaluation of 70:30 poly bone screws after in-vitro degradation, novel biod
Biodegradable, polymer-based systems are playing an increasingly pivotal role in tissue engineering replacement and regeneration. This type of biology-driven materials science is slated to be one of the key research areas of the 21st century. The following aspects are crucial: the development of adequate human cell culture to produce the tissues in adequate polymer scaffold materials; the development of culture technology with which human tissues can be grown ex-vivo in 3D polymer matrices; the development of material technology for producing the degradable, 3D matrices, having mechanical properties similar to natural tissue. In addressing these and similar problems, the book contains chapters on biodegradable polymers, polymeric biomaterials, surface modification for controlling cell-material interactions, scaffold design and processing, biomimetic coatings, biocompatibility evaluation, tissue engineering constructs, cell isolation, characterisation and culture, and controlled release of bioactive agents.
Bioresorbable implants can be processed via conventional polymer processing methods such as extrusion, injection and compressing moulding, solvent spinning or casting. This book addresses issues and highlights recent advances in the use of biodegradable polymers. It is intended for researchers utilizing biodegradable polymers in areas from tissue engineering to controlled release of active pharmaceuticals, as well as industrial processors.
Bioresorbable materials are extensively used for a wide range of biomedical applications from drug delivery to fracture fixation, and may remain in the body for weeks, months or even years. Accurately predicting and evaluating the degradation rate of these materials is critical to their performance and the controlled release of bioactive agents. Degradation rate of bioresorbable materials provides a comprehensive review of the most important techniques in safely predicting and evaluating the degradation rate of polymer, ceramic and composite based biomaterials.Part one provides an introductory review of bioresorbable materials and the biological environment of the body. Chapters in Part two address degradation mechanisms of commonly used materials such as polymers and ceramics. This is followed by chapters on bioresorption test methods and modelling techniques in Part three. Part four discusses factors influencing bioresorbability such as sterilisation, porosity and host response. The final section reviews current clinical applications of bioresorbable materials.With its distinguished editor and multidisciplinary team of international contributors, Degradation rate of bioresorbable materials: prediction and evaluation provides a unique and valuable reference for biomaterials scientists, engineers and students as well as the medical community. - Comprehensively reviews the most pertinent techniques in safely predicting and evaluating the degradation rate of bioresorbable materials - Addresses degradation mechanisms of commonly used materials - Discusses factors influencing bioresorbability such as sterilisation and host response
The articles included in this text highlight the important advances in polymer science that impact tissue engineering. The breadth of polymer science is well represented with the relevance of both polymer chemistry and morphology emphasized in terms of cell and tissue response.
Biopolymer Composites in Electronics examines the current state-of-the-art in the electronic application based on biopolymer composites. Covering the synthesis, dispersion of fillers, characterization and fabrication of the composite materials, the book will help materials scientists and engineers address the challenges posed by the increased use of biopolymeric materials in electronic applications. The influence of preparation techniques on the generation of micro, meso, and nanoscale fillers, and the effect of filler size and dispersion on various biopolymers are discussed in detail. Applications covered include sensors, actuators, optics, fuel cells, photovoltaics, dielectrics, electromagnetic shielding, piezoelectrics, flexible displays, and microwave absorbers. In addition, characterization techniques are discussed and compared, enabling scientists and engineers to make the correct choice of technique. This book is a 'one-stop' reference for researchers, covering the entire state-of-the-art in biopolymer electronics. Written by a collection of expert worldwide contributors from industry, academia, government, and private research institutions, it is an outstanding reference for researchers in the field of biopolymer composites for advanced technologies. - Enables researchers to keep up with the rapid development of biopolymer electronics, which offer light, flexible, and more cost-effective alternatives to conventional materials of solar cells, light-emitting diodes, and transistors - Includes thorough coverage of the physics and chemistry behind biopolymer composites, helping readers to become rapidly acquainted with the fiel - Provides in-depth information on the range of biopolymer applications in electronics, from printed flexible conductors and novel semiconductor components, to intelligent labels, large area displays, and solar panels
This book highlights the latest, cutting-edge advances in implantable biomaterials. It brings together a class of advanced biomaterials in two highly active research areas, namely implants and tissue scaffolds, to underline their respective functional requirements for further development. It is unique in providing a full range of methodological procedures, including materials syntheses, characterisation, cellular tests and mathematical modelling. Covering metallic, ceramic, polymeric and composite materials commonly used in biological applications and clinical therapeutics, it is a valuable resource for anyone wanting to further their understanding of the latest developments in implantable biomaterials. Focusing on biomedical applications in implants and scaffolds, it provides methodological guides to this rapidly growing field. Qing Li and Yiu-Wing Mai are both professors at the University of Sydney, School of Aerospace, Mechanical and Mechatronic Engineering.
Collating otherwise hard-to-get and recently acquired knowledge in one work, this is a comprehensive reference on the synthesis, properties, characterization, and applications of this eco-friendly class of plastics. A group of internationally renowned researchers offer their first-hand experience and knowledge, dealing exclusively with those biodegradable polyesters that have become increasingly important over the past two decades due to environmental concerns on the one hand and newly-devised applications in the biomedical field on the other. The result is an unparalleled overview for the industrial chemist and materials scientist, as well as for developers and researchers in industry and academia alike.
The mechanical properties of whole bones, bone tissue, and the bone-implant interfaces are as important as their morphological and structural aspects. Mechanical Testing of Bone and the Bone-Implant Interface helps you assess these properties by explaining how to do mechanical testing of bone and the bone-implant interface for bone-related research
This book summarizes the properties and applications of conventional and commercially available fiber-forming, bioresorbable polymers, as well as those currently under study, for use as biotextiles. Factors affecting the performance of these biomaterials are presented, and precautionary measures to reduce premature, hydrolytic degradation during manufacturing and processing are discussed. Because of the structural requirements of medical devices and the technological advancements in synthetic fibers and textile technology, the new field of "Biotextiles" has evolved to exploit the potential of various woven, knitted, braided and non-woven textile structures for biomedical applications. Textile substrates provide certain unique mechanical properties to the medical device and because of an inherently high level of porosity, they can encourage cell growth and promote migration and proliferation. Bioresorbable devices that assist in the repair and regeneration of damaged tissues have in recent years replaced many of the permanent prosthetic devices. Thus, the topic of “Bioresorbable Biomaterials” generates much interest and research activity in the field of biomaterials science today. For this reason, the use of bioresorbable polymers as fibers is currently dominating the field of resorbable biomaterials for applications from sutures to tissue engineering scaffolds.