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SYNJARDY XR Drug Profile, 2023

This report focuses on SYNJARDY XR and covers the following critical aspects of this drug:

  • United States patents
  • Expired United States patents
  • FDA Paragraph IV patent challenges
  • District Court patent litigation
  • European supplementary protection certificates (SPCs)
  • Clinical trials
  • Drug prices
  • Finished product suppliers

GLYXAMBI Drug Profile, 2023

This report focuses on GLYXAMBI and covers the following critical aspects of this drug:

  • United States patents
  • Expired United States patents
  • FDA Paragraph IV patent challenges
  • District Court patent litigation
  • Patent Trial and Appeal Board (PTAB) patent cases
  • European supplementary protection certificates (SPCs)
  • Drug prices
  • Finished product suppliers
Choose the drug handbook trusted by nurses for more than 35 years! Mosby's 2023 Nursing Drug Reference makes it easy to find the most vital information on the drugs you administer most frequently. More than 5,000 drugs are profiled — including 35 new entries for drugs recently approved by the FDA. And no other drug guide places a higher emphasis on patient safety, with Black Box Warnings for dangerous adverse reactions, Safety Alerts for situations requiring special attention, and a focus on both common and life-threatening side effects. From nursing pharmacology expert Linda Skidmore-Roth, this perennial bestseller proves there is a difference in drug guides. More than 5,000 generic and trade-name drugs are profiled, covering almost every drug you will administer in practice or in clinicals. Safety Alert icon highlights the most critical drug interactions and side effects. Black Box Warnings provide alerts to FDA warnings of dangerous or life-threatening drug reactions. Nursing Process steps are used as the framework for organizing all nursing care information. Coverage of IV drug administration highlights dosage and IV administration instructions, including safety considerations and Y-site, syringe, and additive compatibilities. Side effects information is organized by body system and identified as common or life threatening, showing signs to watch for during assessments. Alphabetical organization by generic name provides quick and easy access to specific drugs, and a full-color design highlights important information. Complete pharmacokinetic information includes the mechanism and absorption of the drug as well as its action, duration, and excretion. Overview of drug categories explains the safe administration of common classes of drugs, as well as their common side effects and interactions. Flexible, water-resistant cover provides durability in the clinical setting. NEW! Drug monographs for 35 new FDA-approved medications equip you with the latest drug information including generic names, trade names, pronunciations, do-not-confuse drugs, action, uses, contraindications, precautions, dosages and routes, side effects, pharmacokinetics, interactions (including drug/herb, drug/food and drug/lab test), nursing considerations, treatment of overdose, patient/family teaching, and more. NEW! Updates on drug therapies provide the most current information.
Ensure safe and effective drug therapy with this easy-to-use handbook! Saunders Nursing Drug Handbook 2023 provides you with current, detailed information on more than 1,000 generic and 4,000 trade name drugs. This handy, user-friendly guide includes updated uses, dosage forms, warnings, side effects and adverse reactions, IV drug administration, nursing considerations, and much more. Organized alphabetically by generic drug name for quick reference, this book stands out from the others in guiding the nurse through the steps essential to quality patient care. New drug monographs cover 25 new FDA-approved medications! More than 1,000 generic name drugs, encompassing over 4,000 trade name drugs, are organized alphabetically with A-to-Z tabs for quick and easy access. UNIQUE! Herbal information is included in the appendix and on the Evolve website, covering the interactions and effects of commonly encountered herbs. Detailed information for each drug includes side effects listed by frequency, and adverse effects and reactions requiring prompt intervention. Drugs by Disorder are listed in the front of the book for easy reference, showing common disorders and the drugs most often used for treatment. Drug Classifications section features an overview of actions and uses for drug families. Black Box Alerts and High Alert drugs are highlighted to promote safe administration of drugs that pose the greatest risk for patient harm, and Do Not Confuse With warnings call out drug names that sound alike or look alike. Top 100 Drugs list identifies the most frequently administered drugs. Cross-references to the 400 top U.S. brand-name drugs are located throughout the book for easy access. List of newly approved medications in the front of the book makes it easy to locate the latest drugs. Nursing considerations are organized in a functional nursing process framework and include baseline assessment, intervention/evaluation, and patient/family teaching. Information on lifespan and disorder-related dosage variations covers special considerations for pediatric, geriatric, hepatic, and immune- or renal-compromised patients. Extensive IV content includes IV compatibilities/IV incompatibilities and breaks down key information on reconstitution, rate of administration, and storage. IV Compatibility Chart foldout includes comprehensive compatibility information for 65 intravenous drugs. Fixed combinations are included in dosages of each combined drug directly within the individual monographs, to help students understand different drug dose options for specific diseases. Customizable and printable monographs for 100 of the most commonly used drugs are located on Evolve, along with quarterly drug updates.
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries. - Provides background knowledge on type-2 diabetes and its pathophysiology and therapeutic targets down to the molecular level - Explores, in detail, the chemistry or secondary metabolites of the indicated foods that potentially modify diabetes and/or associated diseases - Examines the pharmacological findings on medicinal foods, including available clinical trials
This book represents the invited presentations and some of the posters presented at the conference entitled "In Vitro-In Vivo Relationship (IVIVR) Workshop" held in Sep tember, 1996. The workshop was organized by the IVIVR Cooperative Working Group which has drawn together scientists from a number of organizations and institutions, both academic and industrial. In addition to Elan Corporation, which is a drug delivery com pany specializing in the development of ER (Extended Release) dosage forms, the IVIVR Cooperative Working Group consists of collaborators from the University of Maryland at Baltimore, University College Dublin, Trinity College Dublin, and the University of Not tingham in the UK. The principal collaborators are: Dr. Jackie Butler, Elan Corporation Prof. Owen Corrigan, Trinity College Dublin Dr. lain Cumming, Elan Corporation Dr. John Devane, Elan Corporation Dr. Adrian Dunne, University College Dublin Dr. Stuart Madden, Elan Corporation Dr. Colin Melia, University of Nottingham Mr. Tom O'Hara, Elan Corporation Dr. Deborah Piscitelli, University of Maryland at Baltimore Dr. Araz Raoof, Elan Corporation Mr. Paul Stark, Elan Corporation Dr. David Young, University of Maryland at Baltimore The purpose of the workshop was to discuss new concepts and methods in the devel opment of in vitro-in vivo relationships for ER products. The original idea went back ap proximately 15 months prior to the workshop itself. For some time, the principal collaborators had been working together on various aspects of dosage form development.
The go-to guide for students and nurses alike to promote better patient care! Saunders Nursing Drug Handbook 2020 provides you with essential information on more than 1,000 generic and 4,000 trade name drugs. This handy user-friendly guide features updated Black Box Alerts and comprehensive coverage of IV drug administration, nursing considerations, and fixed combinations. It uniquely guides you through clinical priorities in the practice setting and is organized alphabetically by generic drug name for quick reference. Detailed information for each drug distinguishes side effects and adverse reactions and lists the effect or reaction by frequency of occurrence to allow the nurse to easily identify which are most likely to occur. Plus, new drug monographs cover approximately 32 newly approved drugs by the FDA; and thoroughly updated monographs include new interactions, precautions, and alerts. - Over 1,000 generic name drugs (encompassing over 4,000 trade name drugs) are organized alphabetically with A to Z tabs to make accessing important information quick and easy. - Detailed information for each drug distinguishes side effects and adverse reactions to help you identify which are most likely to occur. - Special text treatment for high-alert drugs that pose the greatest risk for patient harm, as well as an appendix for drug names that sound alike and look alike, help promote safe drug administration. - UNIQUE! Frequently-used herb monographs and herb interactions keep you informed of the effects of commonly encountered herbs.Classifications s - ection features an overview of actions and uses for drug families.T - op 100 Drugs list helps you easily identify the most frequently administered drugs.N - ursing implications are organized in a functional nursing process framework and include headings for Baseline Assessment, Intervention/Evaluation, and Patient/Family Teaching. - Information on lifespan and disorder-related dosage variations equips you with special considerations for pediatric, geriatric, hepatic, and immune-or renal-compromised patients. - Extensively expanded IV content features a heading for IV compatibilities and expanded rates of infusion, reconstitutions, drip rates, test doses, flushing, and incompatibilities. - Fixed combinations are included in dosages of each combined drug directly within the individual monographs to help you understand different drug dose options for specific diseases. - Cross-references to the 400 top U.S. brand-name drugs are located directly in the main section of the book for easier accessibility. - Customizable and printable monographs for 100 of the most commonly used drugs and quarterly drug updates are located on the free Evolve companion site. - Therapeutic and toxic blood level information shows students the patient implications for drug administration. - Comprehensive IV Compatibility Chart foldout arms you with compatibility information for 65 intravenous drugs. - Newly approved drugs are listed in the front of the book for quick and easy access to this timely information. - Highlights the features of a sample drug monograph with callouts to help you understand how to use the book more efficiently.
This classic and bestselling landmark publication, originally published in 1965, examines the dynamic mechanisms, fundamental principles, and physical properties of various chromatographic procedures. It offers methods to characterize, identify, and predict chromatographic phenomena - providing strategies to select the most appropriate separation tools and techniques for specific applications in chemistry, physics, biology, and forensic and environmental science. Written by a world-renowned pioneer in the field, Dynamics of Chromatography contains many worked equations and real-world examples in gas and liquid chromatography. It includes numerous schematic figures for visualization of key concepts, introduces the means to control migration rate differences and zone spreading, and presents a detailed random-walk model for clarification of column processes. It also analyzes flow, diffusion, and kinetic events, stresses the link between theory and practice, and summarizes mathematical quantities and parameters.
Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related areas, it is hoped that this volume will encourage and inspire the continued design and development of novel pharmaceuticals based on Piperidine and its derivatives. Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers. The most commonly used heterocycle among US FDA approved pharmaceuticals, Piperidine is an extremely important building block in the synthesis of medicinal agents. This heterocycle and its derivatives exhibit a number of important functionalities and have been employed variously as CNS modulators, antiaggregants, anticoagulants, antihistamines, anti-cancer drugs and analgesics. - Explores this extremely important heterocycle to a high level of detail - Describes synthesis methods for 70 current drugs based on Piperidine scaffolds - Gives drug designers all the key knowledge required to develop new drugs utilizing Piperidine - Provides pharmacologists a solid overview of the chemical background of existing Piperidine-based drugs