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Survival and dormancy of bacteria; Survival and dormancy of blue-green algae; Survival and dormancy of fungi; Lichens; Protozoan adaptations for survival; Virus survival in natural ecosystems.
The discovery of stress-induced mutagenesis has changed ideas about mutation and evolution, and revealed mutagenic programs that differ from standard spontaneous mutagenesis in rapidly proliferating cells. The stress-induced mutations occur during growth-limiting stress, and can include adaptive mutations that allow growth in the otherwise growth-limiting environment. The stress responses increase mutagenesis specifically when cells are maladapted to their environments, i.e. are stressed, potentially accelerating evolution then. The mutation mechanism also includes temporary suspension of post-synthesis mismatch repair, resembling mutagenesis characteristic of some cancers. Stress-induced mutation mechanisms may provide important models for genome instability underlying some cancers and genetic diseases, resistance to chemotherapeutic and antibiotic drugs, pathogenicity of microbes, and many other important evolutionary processes. This book covers pathways of stress-induced mutagenesis in all systems. The principle focus is mammalian systems, but much of what is known of these pathways comes from non-mammalian systems.
This text on viable but non-culturable organisms provides information on topics including: morphological changes; the role of membranes; genetics and genetic regulation; molecular methods for detection; as well as survival dominancy and related phenomena. The main purpose of the text is to elucidate the phenomenon and to distinguish it from other seemingly related but different phenomena such as spore formation, dormancy, starvation, and injury. It covers a cross section of morphology, metabolism, genetics, ecology and epidemiology.
This volume presents a comprehensive collection of methods that have been instrumental to the current understanding of bacterial persisters. Chapters in the book cover topics ranging from general methods for measuring persister levels in Escherichia coli cultures, protocols for the determination of the persister subpopulation in Candida albicans, quantitative measurements of Type I and Type II persisters using ScanLag, to in vitro and in vivo models for the study of the intracellular activity of antibiotics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacterial Persistence: Methods and Protocols brings together the most respected researchers in bacterial persistence whose studies will remain vital to understanding this field for many years to come.
An in-depth view of the panspermia hypothesis examined against the latest knowledge of planetary formation and related processes. Panspermia is the concept that life can be passively transported through space on various bodies and seed, habitable planets and moons, which we are beginning to learn may exist in large numbers. It is an old idea, but not popular with those who prefer that life on Earth started on Earth, an alternative, also unproven hypothesis. This book updates the concept of panspermia in the light of new evidence on planet formation, molecular clouds, solar system motions, supernovae ejection mechanisms, etc. Thus, it is to be a book about newly understood prospects for the movement of life through space. The novel approach presented in this book gives new insights into the panspermia theory and its connection with planetary formation and the evolution of galaxies. This offers a good starting point for future research proposals about exolife and a better perspective for empirical scrutiny of panspermia theory. Also, the key to understanding life in the universe is to understand that the planetary formation process is convolved with the evolution of stellar systems in their galactic environment. The book provides the synthesis of all these elements and gives the readers an up-to-date insight on how panspermia might fit into the big picture. Audience Given the intrinsic interdisciplinary nature of the panspermia hypothesis the book will have a wide audience across various scientific disciplines covering astronomy, biology, physics and chemistry. Apart from scientists, the book will appeal to engineers who are involved in planning and realization of future space missions.
This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of basic and applied research fields, as well as having industrial, medical and biotechnological implications. - Individual chapters provided by leading international scientists in the field yield insightful, concise and stimulating reviews - Provides researchers with an overview and synthesis of the latest research - Each chapter begins with a brief 200 word Summary/Abstract detailing the topic and focus of the chapter, as well as the concepts to be addressed - Allows researchers to see at a glance what each chapter will cover - Each chapter includes a Research Focus Box - Identifies important problems that still need to be solved and areas that require further investigation
The processes and mechanisms that control the growth of woody plants are of crucial importance for both economic and biological reasons. The comprehensive coverage of Growth Control in Woody Plants includes discussion of the growth controlling factors in both reproductive structures (flowers, fruit, seeds, pollen, etc.) and vegetative organs (stems, branches, leaves, and roots). Other major topics covered include seed germination, seedling growth, physiological and environmental regulation of growth, cultural practices, and biotechnology.This comprehensive treatment of the many factors that control the growth of woody plants can serve both as a valuable text and as a frequently used reference.* Includes comprehensive representation of a broad subject* Provides thorough bibliographic coverage * Well illustrated* Serves as a vital companion to Physiology of Woody Plants, Second Edition
Annual desert plant species of unrelated taxa in the Negev Desert of Israel have developed complementary sets of adaptations and survival strategies as ecological equivalents with physiological, morphological and anatomical resemblances, in the various stages of their life cycles. After 40 years of research in hot deserts Yitzchak Gutterman provides a comprehensive treatise of such adaptations and strategies. In doing so he covers the following topics: post-maturation primary seed dormancy, which prevents germination of maturing seeds before the summer; seed dispersal mechanisms with escape or protection strategies; cautious or opportunistic germination strategies; seedling drought tolerance. The day-length is an important factor in regulating flowering as well as the phenotypic plasticity of seed germination which is also affected by maternal factors.
Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.
Extremophiles have unique physiological properties, thus considered to be ideal candidates for industrial development. This book present concepts on cold-adapted microorganisms, centered on four different aspects - (i) diversity of cold adapted microbes (ii) their ecology, physiology and metabolism (iii) omics research in the field and (iv) their potential applications. This volume collates the recent developments and innovations with respect to these microorganisms. This book is meant for researchers, biochemists, industries, and government agencies interested in cold active microbes and their products. Also, would be of interest to NGOs and progressive farmers which are working for higher altitude ecosystems throughout the globe.