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Submicroscopic Structure of the Inner Ear focuses on the submicroscopic structure of the inner ear of mammals, as investigated in guinea pigs, cats, chinchillas, squirrel-monkeys, and rats. This book consists of experimental investigations, such as the efferent innervation of the organ of Corti; ototoxicity of some antibiotics; acoustic trauma; and circulation of the labyrinthine fluids. Investigations on the human labyrinth, normal and affected by Meniere's disease, are also covered. This text likewise describes the combined electron-microscopic and electrophysiological research studies that provide a basis for a correlation of the submicroscopic structure and function of the sensory cells. A review of the main light-microscopic features is included for those who are not familiar with the morphology of the inner ear. This publication is intended for students or individuals working on the morphology of the ear, but is also a good reference for anatomists, otologists, zoologists, psychologists, and neurophysiologists interested in the structure of the inner ear.
Basic Aspects of Central Vestibular Mechanisms
Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its third edition serves as a comprehensive resource to students and researchers alike.
In planning The Handbook volumes on Audition, we, the editors, made the decision that there should be many authors, each writing about the work in the field that he knew best through his own research, rather than a few authors who would review areas of research with which they lacked first hand familiarity. For the purposes of the chapters on Audition, sensory physiology has been defined very broadly to include studies from the many disciplines that contribute to our understanding of the structures concerned with hearing and the processes that take place in these structures in man and in lower animals. A number of chapters on special topics have been included in order to present information that might not be covered by the usual chapters dealing with anatomical, physi ological and behavioral aspects of hearing. We wish to thank all authors of the volumes on Audition for the contributions that they have made. We feel confident that their efforts will also be appreciated by the many scientists and clinicians who will make use of the Handbook for many years to come. WOLF D. KEIDEL WILLIAM D. NEFF Erlangen Bloomington August 1974 Contents Introduction. By G. v. BEKESY t. With 3 Figures. . . . . . . . 1 Chapter 1 Consideration of the Acoustic Stimulus. By R. R. PFEIFFER. With Chapter 2 19 Figures. . . . . . . . . . . . . . . . . . . . . . . . . 9 Comparative Anatomy of the Middle Ear. By O. W. HENSON Jr. With Chapter 3 23 Figures. . . . . . . . . . . . . . . . . . . . . . . 39 . . . . .
In this definitive work, Ernest Glen Wever establishes the evolutionary importance of the reptile ear as the origin of the higher type of auditory apparatus shared by man and the mammals. Tracing the development of the auditory receptor in the living reptiles, he examines the use of a variety of mechanisms and principles of action by that receptor. While some of the material in this book has appeared previously in journal articles, most of it is presented here for the first time. Basing this study on his twenty years of research at Princeton's Auditory Research Laboratories, Professor Wever treats in anatomical and functional detail the auditory mechanism in about 250 species and subspecies of reptiles. The anatomical treatment rests on dissections and histological examinations of the ears in serial section, and portrays the relevant features in drawings that represent particular views of reconstructions. The author evaluates the performance of thesse ears electrophysiologically, in terms of the electrical potentials of the cochlea, paying particular attention to problems of the transmission of vibrations inward to the cochlea and the actions there in stimulating the sensory cells. Professor Wever finds that the cochlea emerged independently from the non-auditory labyrinth in three different vertebrate groups: fishes, amphibians, and reptiles. It was among the reptiles, however, that the vertebrate ear took on a more advanced configuration from which it further evolved along separate lineages in the birds and mammals. Ernest Glen Wever is Eugene Higgins Professor of Psychology Emeritus at Princeton University. Originally published in 1978. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
It is easy to underrate the importance of a sensory system whose receptor is buried deep within the skull and of whose performance we are usually not aware. It is only when it malfunctions that we know we have a ves tibular system! Unraveling the mechanisms by which activation of the vestibular labyrinth exerts its varied effects presents a great challenge, which increasing numbers of investigators are rushing to meet. At this time a period of transition appears to have been reached. On the one hand, physiological and anatomical techniques have provided extensive information about the properties of the receptor and of some of the path ways that link it to the musculature. On the other hand, extensive be havioral and psychophysical studies provide different insights into the mechanisms involved in vestibular reflexes. Until recently there has been relatively 1ittle interaction between the practitioners of these two widely different approaches. It has been our goal to assess and describe the progress that has been made in both areas and, when possible, to make a synthesis of the results. As will be seen, numerous questions are raised in the process, and we hope that they will help in pointing the way to further investigations. We are grateful to the authors and publishers who gave permission to reproduce many of the figures, and to our colleagues who have read and commented on all or part of the manuscript. Victor J.
This third edition of the standard reference on the nervous system of the rat is a complete and updated revision of the 1994 second edition. All chapters have been extensively updated, and new chapters added covering early segmentation, growth factors, and glia. The book is now aligned with the data available in the Rat Brain in Stereotaxic Coordinates, making it an excellent companion to this bestselling atlas. Physiological data, functional concepts, and correlates to human anatomy and function round out the new edition. Designed to be used in conjunction with the bestselling Rat Brain in Stereotaxic Coordinates New to this edition is inclusion of physiological data, functional concepts, and correlates to human anatomy and function in each chapter Contains new chapters on early segmentation of the central nervous system, growth factors and glia